List of Schedule I controlled substances (U.S.)

This is the list of Schedule I controlled substances in the United States as defined by the Controlled Substances Act.^[1] The following findings are required for substances to be placed in this schedule:^[2]

1. The drug or other substance has a high potential for abuse.
2. The drug or other substance has no currently accepted medical use in treatment in the United States.
3. There is a lack of accepted safety for use of the drug or other substance under medical supervision.

The complete list of Schedule I substances is as follows.^[1] The Administrative Controlled Substances Code Number for each substance is included.

Opioids

ACSCN	Drug
9815	Acetyl-alpha-methylfentanyl[3]
9601	Acetylmethadol[4][note 1]
9821	Acetylfentanyl[5]
9811	Acryl fentanyl[6]
9551	AH-7921[7]
9602	Allylprodine[4][note 1]
9603	Alphacetylmethadol (except levo-alphacetylmethadol also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM)[8]
9604	Alphameprodine[4][note 1]
9605	Alphamethadol[4][note 1]
9814	Alpha-methylfentanyl[9]
9832	Alpha-methylthiofentanyl[3]
9606	Benzethidine[4][note 1]
9607	Betacetylmethadol[4][note 1]
9830	Beta-hydroxyfentanyl[3]
9831	Beta-hydroxy-3-methylfentanyl[10]
9836	Beta-hydroxythiofentanyl[11]
9608	Betameprodine[4][note 1]
9609	Betamethadol[4][note 1]
9856	Beta-methylfentanyl[12]
9842	Beta-phenylfentanyl[12]
9611	Betaprodine[4][note 1]
9098	Brorphine[13]
9822	Butyryl Fentanyl[14]
9612	Clonitazene[4][note 1]
9844	Crotonylfentanyl[15]
9847	Cyclopentyl fentanyl[16]
9845	Cyclopropyl fentanyl[17]
9613	Dextromoramide[4][note 1]
9615	Diampromide[4][note 1]
9616	Diethylthiambutene[4][note 1]
9168	Difenoxin[18]
9617	Dimenoxadol[4][note 1]
9618	Dimepheptanol[4][note 1]
9619	Dimethylthiambutene[4][note 1]
9621	Dioxaphetyl butyrate[4][note 1]
9622	Dipipanone[4][note 1]
9623	Ethylmethylthiambutene[4][note 1]
9624	Etonitazene[4][note 1]
9625	Etoxeridine[4][note 1]
9851	Fentanyl carbamate[19]
9824	4-Fluoroisobutyryl fentanyl[19]
9855	2′-Fluoro ortho-fluorofentanyl[12]
9834	Furanyl fentanyl[6]
9626	Furethidine[4][note 1]
9627	Hydroxypethidine[4][note 1]
9827	Isobutrylfentanyl[16]
9614	Isotonitazene[20]
9628	Ketobemidone[4][note 1]
9629	Levomoramide[4][note 1]
9631	Levophenacylmorphan[4][note 1]
9825	Methoxyacetyl fentanyl[17]
9819	4′-Methyl acetyl fentanyl[12]
9813	3-Methylfentanyl
9833	3-methylthiofentanyl
9757	Metonitazene[21]
9632	Morpheridine[4][note 1]
9661	MPPP[22]
9560	MT-45[23]
9633	Noracymethadol[4][note 1]
9634	Norlevorphanol[4][note 1]
9635	Normethadone[4][note 1]
9636	Norpipanone[4][note 1]
9838	Ocfentanil[6]
9852	ortho-Fluoroacryl fentanyl[19]
9846	ortho-Fluorobutyryl fentanyl[12]
9816	ortho-Fluorofentanyl[12]
9853	ortho-Fluoroisobutyryl fentanyl[19]
9848	ortho-Methyl acetylfentanyl[12]
9820	ortho-Methyl methoxyacetyl fentanyl[12]
9826	para-Chloroisobutyryl fentanyl[24]
9823	para-Fluorobutyryl fentanyl[12]
9812	Para-fluorofentanyl[3]
9854	para-Fluoro furanyl fentanyl[19]
9837	para-Methoxybutyryl fentanyl[16]
9817	para-Methylfentanyl[12]
9663	PEPAP[22]
9637	Phenadoxone[4][note 1]
9638	Phenampromide[4][note 1]
9647	Phenomorphan[4][note 1]
9641	Phenoperidine[4][note 1]
9841	Benzoylfentanyl[12]
9642	Piritramide[4][note 1]
9643	Proheptazine[4][note 1]
9644	Properidine[4][note 1]
9649	Propiram[25]
9645	Racemoramide[4][note 1]
9843	Tetrahydrofuranyl fentanyl[6]
9835	Thiofentanyl[3]
9839	Thiofuranyl fentanyl[12]
9750	Tilidine[26]
9646	Trimeperidine[4][note 1]
9547	U-47700[14]
9840	Valerylfentanyl[16]
9873	Zipeprol[27]

Opium derivatives

ACSCN	Drug
9319	Acetorphine[4][note 1]
9051	Acetyldihydrocodeine[4][note 1]
9052	Benzylmorphine[4][note 1]
9070	Codeine methylbromide[4][note 1]
9053	Codeine-N-Oxide[4][note 1]
9054	Cyprenorphine[4][note 1]
9055	Desomorphine[4][note 1]
9145	Dihydromorphine[4][note 1]
9335	Drotebanol[28]
9056	Etorphine (except hydrochloride salt)[29]
9200	Heroin[4][note 1]
9301	Hydromorphinol[4][note 1]
9302	Methyldesorphine[4][note 1]
9304	Methyldihydromorphine[4][note 1]
9305	Morphine methylbromide[4][note 1]
9306	Morphine methylsulfonate[4][note 1]
9307	Morphine-N-Oxide[4][note 1]
9308	Myrophine[4][note 1]
9309	Nicocodeine[4][note 1]
9312	Nicomorphine[4][note 1]
9313	Normorphine[4][note 1]
9314	Pholcodine[4][note 1]
9315	Thebacon[4][note 1]

Hallucinogenic or psychedelic substances

ACSCN	Drug
7249	α-ET[30]
7391	4-bromo-2,5-dimethoxyamphetamine (DOB)[31]
7392	2C-B[32]
7396	2,5-dimethoxyamphetamine (2,5-DMA)[31]
7399	DOET[33]
7348	2C-T-7[34]
7411	4-methoxyamphetamine (PMA)[31]
7401	5-methoxy-3,4-methylenedioxyamphetamine (MMDA)[4][note 1]
7395	4-methyl-2,5-dimethoxyamphetamine (DOM; STP)[4][note 1]
7400	3,4-methylenedioxyamphetamine (MDA)[4][note 1]
7405	3,4-methylenedioxymethamphetamine (MDMA)[35]
7404	3,4-methylenedioxy-N-ethylamphetamine (MDEA; MDE)[36]
7402	N-hydroxy-3,4-methylenedioxyamphetamine (N-hydroxy MDA)[36]
7390	3,4,5-trimethoxyamphetamine (TMA)[4][note 1]
7431	5-MeO-DMT[37]
7432	Alpha-methyltryptamine (αMT)[38]
7433	Bufotenine[4][note 1]
7434	Diethyltryptamine (DET)[4][note 1]
7435	Dimethyltryptamine (DMT)[4][note 1]
7439	5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), its isomers, salts and salts of isomers[38]
7260	Ibogaine[4][note 1]
7315	Lysergic acid diethylamide (LSD)[4][note 1]
7360	Marihuana[4][note 1]
7381	Mescaline[4][note 1]
7374	Parahexyl[39]
7415	Peyote[4][note 1]
7482	N-ethyl-3-piperidyl benzilate[4][note 1]
7484	N-methyl-3-piperidyl benzilate[4][note 1]
7437	Psilocybin[4][note 1]
7438	Psilocin[4][note 1]
7370	Tetrahydrocannabinol (THC)
7455	Ethylamine analog of phencyclidine (Eticyclidine; PCE)
7458	Pyrrolidine analog of phencyclidine (PCPy)
7470	Thiophene analog of phencyclidine (TCP)
7473	1-[1-(2-thienyl)cyclohexyl]pyrrolidine (TCPy)
1259	3-Methylmethcathinone (3-MMC)[40]
1248	4-Methylmethcathinone (Mephedrone)
7535	3,4-methylenedioxypyrovalerone (MDPV)
7509	2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C-E)
7508	2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C-D)
7519	2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C-C)
7518	2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C-I)
7385	2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-2)
7532	2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C-T-4)
7517	2-(2,5-Dimethoxyphenyl)ethanamine (2C-H)
7521	2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C-N)
7524	2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C-P)
7540	3,4-Methylenedioxy-N-methylcathinone (methylone)

Depressants

ACSCN	Drug
2010	gamma-Hydroxybutyric acid (GHB; sodium oxybate; sodium oxybutyrate) except formulations in an FDA-approved drug product are Schedule III
2572	Mecloqualone
2565	Methaqualone

Stimulants

ACSCN	Drug
1585	Aminorex (aminoxaphen; 2-amino-5-phenyl-2- oxazoline; or 4,5-dihydro-5-phenly-2-oxazolamine)
7493	N-benzylpiperazine (some other names: BZP; 1-benzylpiperazine), its optical isomers, salts and salts of isomers
1235	Cathinone
1503	Fenethylline
1237	Methcathinone (Some other names: 2-(methylamino)-propiophenone; alpha-(methylamino)propiophenone; 2-(methylamino)-1-phenylpropan-1-one; alpha-N-methylaminopropiophenone; monomethylpropion; ephedrone; N-methylcathinone; methylcathinone; AL-464; AL-422; AL-463 and UR1432), its salts, optical isomers and salts of optical isomers
1590	(±)-cis-4-methylaminorex
1475	N-ethylamphetamine
1480	N,N-dimethylamphetamine (also known as N,N-alpha-trimethyl-benzeneethanamine; N,N-alpha-trimethylphenethylamine)
7543	N-Ethylpentylone (ephylone, N-1-(1,3-benzodioxol-5-yl)-2-(ethylamino)-1-pentanone))[41]
7246	N-Ethylhexedrone[42] (hexen)
7544	alpha-Pyrrolidinohexanophenone (α-PHP)[42]
7551	alpha-Pyrrolidinoisohexanophenone (also known as α-PHiP; α-PiHP) [40]
7245	4-Methyl-alpha-ethylaminopentiophenone (4-MEAP)[42]
7446	4'-Methyl-alpha-pyrrolidinohexiophenone (MPHP)[42]
7548	alpha-Pyrrolidinoheptaphenone (PV8)[42]
7443	4-Chloro-alpha-pyrrolidinovalerophenone (4-chloro-α-PVP)[42]
1233	3-Fluoro-N-methylcathinone (3-FMC; 1-(3-fluorophenyl)-2-(methylamino)propan-1-one)
1238	4-Fluoro-N-methylcathinone (4-FMC, flephedrone, 1-(4-fluorophenyl)-2-(methylamino)propan-1-one)
1246	Pentedrone (α-methylaminovalerophenone, 2-(methylamino)-1-phenylpentan-1-one)
1249	4-Methyl-N-ethylcathinone (4-MEC, 2-(ethylamino)-1-(4-methylphenyl)propan-1-one)
1258	Naphyrone (naphthylpyrovalerone; 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one)
7498	4-Methyl-alphapyrrolidinopropiophenone (4-MePPP, MePPP, 4-methyl-α-pyrrolidinopropiophenone,1-(4-methylphenyl)-2-(pyrrolidin-1-yl)-propan-1-one)
7541	Butylone (bk-MBDB, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)butan-1-one)
7542	Pentylone (bk-MBDP, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one)
7545	alpha-pyrrolidinopentiophenone (α-PVP, α-pyrrolidinovalerophenone, 1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one)
7546	alpha-pyrrolidinobutiophenone (α-PBP, 1-phenyl-2-(pyrrolidin-1-yl)butan-1-one)

Cannabimimetic agents

ACSCN	Drug
7297	5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP-47,497)
7298	5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP-47,497 C8-homolog)
7118	1-pentyl-3-(1-naphthoyl)indole (JWH-018 and AM678)
7173	1-butyl-3-(1-naphthoyl)indole (JWH-073)
7019	1-hexyl-3-(1-naphthoyl)indole (JWH-019)
7200	1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH-200)
6250	1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH-250)
7081	1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH-081)
7122	1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH-122)
7398	1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH-398)
7201	1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201)
7694	1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM694)
7104	1-pentyl-3-[(4-methoxy)-benzoyl]indole (SR-19 and RCS-4)
7008	1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole 7008 (SR-18 and RCS-8)
7203	1-pentyl-3-(2-chlorophenylacetyl)indole (JWH-203)
7144	(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (UR-144, 1-pentyl-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7011	[1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, its optical, positional, and geometric isomers, salts and salts of isomers (5-fluoro-UR-144, 5-F-UR-144, XLR-11, 1-(5-fluoro-pentyl)-3-(2,2,3,3-tetramethylcyclopropoyl)indole)
7048	N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide, its optical, positional, and geometric isomers, salts and salts of isomers (APINACA, AKB-48)
7222	Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate (QUPIC, PB-22)[43]
7225	Quinolin-8-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate (5-fluoro-PB-22; 5F-PB-22)[43]
7012	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA)[43]
7035	N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (ADB-PINACA)[43]
7031	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (AB-CHMINACA)[44]
7023	N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA)[44]
7024	[1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201)[44]
7034	2-(1-(5-Fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (5F-ADB, 5F-MDMB-PINACA)[45]
7033	Methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3-methylbutanoate (5F-AMB)[45]
7049	N-(Adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-APINACA, 5F-AKB48)[45]
7010	N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (ADB-FUBINACA)[45]
7042	Methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-CHMICA, MMB-CHMINACA)[45]
7020	Methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (MDMB-FUBINACA)[45]
7032	N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (MAB-CHMINACA; ADB-CHMINACA)[46]
7036	ethyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate (5F-EDMB-PINACA)[47]
7041	methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate (5F-MDMB-PICA)[47]
7047	N-(adamantan-1-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (FUB-AKB48; FUB-APINACA; AKB48 N-(4-FLUOROBENZYL))[47]
7083	1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide (5F-CUMYL-PINACA; SGT-25)[47]
7014	(1-(4-fluorobenzyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl) methanone (FUB-144)[47]
7021	Methyl 2-(1-(4-fluorobenzyl)-1Hindazole-3-carboxamido)-3-methylbutanoate (FUB–AMB, MMB– FUBINACA, AMB–FUBINACA)
7025	5F-AB-PINACA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide)
7044	MMB-CHMICA (AMB-CHMICA, methyl 2-(1-(cyclohexylmethyl)-1H-indole-3-carboxamido)-3-methylbutanoate)
7085	5F-CUMYL-P7AICA (1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1 H-pyrrolo[2,3-b]pyridine-3-carboxamide)
7089	4-CN-CUMYL-BUTINACA (1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide, 4-cyano-CUMYL-BUTINACA, 4-CN-CUMYL BINACA, CUMYL-4CN-BINACA, SGT-78)
7221	NM-2201 (CBL2201, Naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate)
7027	ADB-BUTINACA (N-[(2S)-1-amino-3,3-dimethyl-1-oxobutan-2-yl]-1-butyl-1H-indazole-3-carboxamide)[40]

See also

• List of Schedule II controlled substances (U.S.)
• List of Schedule III controlled substances (U.S.)
• List of Schedule IV controlled substances (U.S.)
• List of Schedule V controlled substances (U.S.)

Notes

1. This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.