Flephedrone

Flephedrone, also known as 4-fluoromethcathinone (4-FMC), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug starting in 2008.^[3]

Flephedrone

Clinical data
Routes of administration	Oral, insufflation, vaporized
Legal status
Legal status	BR: Class F2 (Prohibited psychotropics)[1] DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B US: Schedule I[2] Illegal in Denmark,[citation needed] Poland
Identifiers
IUPAC name 1-(4-Fluorophenyl)-2-(methylamino)propan-1-one
CAS Number	447-40-5 Y
PubChem CID	49853406
ChemSpider	21477355 Y
UNII	BA88IEZ2HF
CompTox Dashboard (EPA)	DTXSID401028417
Chemical and physical data
Formula	C10H12FNO
Molar mass	181.210 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES CNC(C)C(=O)c(cc1)ccc1F
InChI InChI=1S/C10H12FNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3 Y Key:MWKQPIROPJSFRI-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Toxicity

Flephedrone has only a short history of human use and its toxicity is not well established.^[4]

Legality

Flephedrone has been illegal in Denmark since December 2008.^{[citation needed]}

Flephedrone has been illegal in the UK since April 2010. Flephedrone has been illegal in the Lithuania since April 2010. Flephedrone is illegal in Brazil since 2017 as an analogue or derivative of cathinone. Flephedrone is most likely illegal in Australia as an analogue or derivative of cathinone.

Flephedrone has been illegal in Poland since April 2010.^[5]

Flephedrone has been classed as a narcotic in Sweden since October 2010.^[6]

In the United States, flephedrone is temporarily listed as a Schedule I controlled substance.^[2] It is permanently listed as a Schedule I controlled substance in Florida,^[7] Georgia, and Pennsylvania.^[8]

As of October 2015 4-FMC is a controlled substance in China.^[9]

See also

• 3-Fluoromethcathinone (3-FMC)

References

1. Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
2. "Schedules of Controlled Substances: Temporary Placement of 10 Synthetic Cathinones Into Schedule I". Federal Register. The Daily Journal of the United States Government. 7 March 2014.
3. Archer RP (March 2009). "Fluoromethcathinone, a new substance of abuse". Forensic Science International. 185 (1–3): 10–20. doi:10.1016/j.forsciint.2008.11.013. PMID 19195800.
4. Thornton SL, Gerona RR, Tomaszewski CA (September 2012). "Psychosis from a bath salt product containing flephedrone and MDPV with serum, urine, and product quantification". Journal of Medical Toxicology. 8 (3): 310–3. doi:10.1007/s13181-012-0232-4. PMC 3550171. PMID 22528592.
5. "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. Retrieved 17 June 2011.
6. "Läkemedelsverkets författningssamling" [The Swedish Medicines Agency's constitutional collection] (PDF). Medical Products Agency (Sweden), Läkemedelsverkets författningssamling (in Swedish).
7. "Notice of Emergency Rule" (PDF). Department of Business and Professional Regulation. State of Florida.
8. "Sensate Bill 1006". The General Assembly of Pennsylvania. 2011.
9. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.