List of Schedule III controlled substances (U.S.)

This is the list of Schedule III controlled substances in the United States as defined by the Controlled Substances Act at 21 U.S.C. § 812(c) and 21 CFR 1308.13. The following findings are required for substances to be placed in this schedule:^[1]

1. The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II.
2. The drug or other substance has a currently^[2] accepted medical use in treatment in the United States.
3. Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence.

The complete list of Schedule III substances is as follows. The Administrative Controlled Substances Code Number and Federal Register citation for each substance is included.

Stimulants

ACSCN	Drug
1405	See 21 CFR 1308.13(b)(1)
1228	Benzphetamine[3]
1645	Chlorphentermine[3]
1647	Clortermine[3]
1615	Phendimetrazine[3]

Depressants

ACSCN	Drug
2100	Any derivative of barbituric acid[4][note 1]
2510	Chlorhexadol[4][note 1]
2020	Embutramide[5]
2012	FDA-approved oxybate products[6]
2261	Perampanel[7]
7285	Ketamine[8]
7300	Lysergic acid[4][note 1]
7310	Lysergic acid amide[4][note 1]
2575	Methyprylon[4][note 1]
2600	Sulfondiethylmethane[4][note 1]
2605	Sulfonethylmethane[4][note 1]
2610	Sulfonmethane[4][note 1]
7295	Tiletamine and zolazepam[9]

Others

ACSCN	Drug
9400	Nalorphine[4][note 1]

Narcotics

ACSCN	Drug
9803	Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium[4][note 1]
9804	Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[4][note 1]
9807	Not more than 1.8 grams of dihydrocodeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active nonnarcotic ingredients in recognized therapeutic amounts[4][note 1]
9808	Not more than 300 milligrams of ethylmorphine per 100 milliliters or not more than 15 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[4][note 1]
9809	Not more than 500 milligrams of opium per 100 milliliters or per 100 grams or not more than 25 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[4][note 1]
9810	Not more than 50 milligrams of morphine per 100 milliliters or per 100 grams, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts[4][note 1]
9064	Buprenorphine[10]

Steroids

ACSCN	Drug
4000	Anabolic steroids

Hallucinogens

ACSCN	Drug
7369	Dronabinol in sesame oil and encapsulated in a soft gelatin capsule[11]

See also

• List of Schedule I controlled substances (U.S.)
• List of Schedule II controlled substances (U.S.)
• List of Schedule IV controlled substances (U.S.)
• List of Schedule V controlled substances (U.S.)

Notes

1. This substance was expressly scheduled by the Controlled Substances Act on October 27, 1970. The 1974 Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in the Code of Federal Regulations.

References

1. 21 U.S.C. § 812(b)(3) retrieved September 3, 2014
2. The use of the term "currently" in Wikipedia is deprecated per MOS:RELTIME, however its presence here is a direct quotation of the referenced Act.
3. Ingersoll, John (June 15, 1973). "Schedules of Controlled Substances; Placement of Benzphetamine, Chlorphentermine, Clotermine, Diethylpropion, Mazindol, Phendimetrazine, and Phentermine in Schedule III" (PDF). Isomer Design. Bureau of Narcotics and Dangerous Drugs. Archived (PDF) from the original on May 19, 2019. Retrieved January 16, 2023.
4. Bartels Jr., John R. (June 20, 1974). "PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication" (PDF). Government Publishing Office. Drug Enforcement Administration. Archived from the original (PDF) on September 6, 2023. Retrieved September 6, 2023.
5. Leonhart, Michele (August 29, 2006). "Schedules of Controlled Substances: Placement of Embutramide Into Schedule III". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
6. Marshall, Donnie (March 13, 2000). "Schedules of Controlled Substances: Addition of Gamma-Hydroxybutyric Acid to Schedule I". Federal Register. Drug Enforcement Administration.
7. Harrigan, Thomas (October 22, 2013). "Department of Justice. Drug Enforcement Administration. Schedules of Controlled Substances: Placement of Perampanel into Schedule III" (PDF). Federal Register. 78 (204). Office of the Federal Register, National Archives and Records Administration: 62500–62506. Retrieved 22 February 2014.
8. Marshall, Donnie (July 13, 1999). "Schedules of Controlled Substances: Placement of Ketamine into Schedule III". Federal Register. Drug Enforcement Administration. Archived from the original on September 6, 2023. Retrieved September 6, 2023.
9. Lawn, John (January 21, 1987). "Schedules of Controlled Substances: Placement of Preparations Which Contain Both Tiletamine and Zolazepam into Schedule III" (PDF). Isomer Design. Drug Enforcement Administration. Archived (PDF) from the original on March 3, 2022. Retrieved January 16, 2023.
10. Brown, John (October 7, 2002). "Schedules of Controlled Substances: Rescheduling of Buprenorphine From Schedule V to Schedule III". Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.
11. Marshall, Donnie (July 2, 1999). "Schedules of controlled substances: rescheduling of the Food and Drug Administration approved product containing synthetic dronabinol in sesame oil and encapsulated in soft gelatin capsules from schedule II to schedule III" (PDF). Federal Register. Drug Enforcement Administration. Retrieved January 16, 2023.