4'-Methyl-α-pyrrolidinopropiophenone

For other uses, see MPPP (disambiguation).

Not to be confused with desmethylprodine (opioid drug with acronym MPPP), MPTP (neurotoxic impurity of desmethylprodine synthesis) or MPP⁺ (neurotoxic metabolite of MPTP).

4'-Methyl-α-pyrrolidinopropiophenone (4-MePPP, MPPP or MαPPP) is a stimulant drug and substituted cathinone. It is structurally very similar to α-PPP, with only one added methyl group in the para position on the phenyl ring. 4-MePPP was sold in Germany as a designer drug in the late 1990s and early 2000s,^[2][3][4] along with a number of other pyrrolidinophenone derivatives.^[5][6] Although it has never achieved the same international popularity as its better-known relations α-PPP and MDPV, 4-MePPP is still sometimes found as an ingredient of grey-market "bath salt" blends^[7] such as "NRG-3".^[7]

4'-Methyl-α-pyrrolidinopropiophenone

Legal status
Legal status	DE: Anlage I (Authorized scientific use only) UK: Class B US: Schedule I Banned in Sweden [1]
Identifiers
IUPAC name (RS)-1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-propanone
CAS Number	28117-80-8 1313393-58-6 (hydrochloride)
PubChem CID	6430745
ChemSpider	4936084
UNII	0TY023967I
CompTox Dashboard (EPA)	DTXSID80891438
Chemical and physical data
Formula	C14H19NO
Molar mass	217.312 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1=CC=C(C=C1)C(=O)C(C)N2CCCC2
InChI InChI=1S/C14H19NO/c1-11-5-7-13(8-6-11)14(16)12(2)15-9-3-4-10-15/h5-8,12H,3-4,9-10H2,1-2H3 Key:APSJUNFBAXIXLK-UHFFFAOYSA-N

Legality

In the United States 4-MePPP is considered a schedule 1 controlled substance as an positional isomer of alpha-pyrrolidinopentiophenone (α-PVP)^[8]

See also

• α-Pyrrolidinopropiophenone (α-PPP)
• 4'-Methoxy-α-pyrrolidinopropiophenone (MOPPP)
• 3,4-Methylenedioxy-α-pyrrolidinopropiophenone (MDPPP)
• 3',4'-Methylenedioxy-α-pyrrolidinobutiophenone (MDPBP)