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Chemical compound (analgesic drug) From Wikipedia, the free encyclopedia
Metonitazene is an analgesic compound related to etonitazene,[2][3] which was first reported in 1957,[4] and has been shown to have approximately 1000 times the potency of morphine by central routes of administration,[5] but if used orally it has been shown to have approximately 10 times the potency of morphine.[6]
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| Formula | C21H26N4O3 |
| Molar mass | 382.464 g·mol−1 |
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Its effects are similar to other opioids such as fentanyl and heroin, including analgesia, euphoria, and sleepiness.[6][7] Adverse effects include vomiting, and respiratory depression that can potentially be fatal.[8] Because of high dependency potential and dangerous adverse effects it has never been introduced into pharmacotherapy. It is instead commonly used in the illicit manufacture of counterfeit oxycodone opioid pills.[9]
In the United States, metonitazene is a Schedule I controlled substance under the Controlled Substances Act.
Metonitazene is not controlled under the 1971 Convention on Psychotropic Substances; however, in many countries possession or intent to sell for human consumption might be prosecuted under several analog acts.
Metonitazene became a Class A drug in the UK on 20th March 2024.
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