SLC17A6

Član 6 porodice rastvornih nosača 17 (vezikulski glutamat-transporter) je protein koji je kod ljudi kodiran genom SLC17A6. ^[5]

Aminokiselinska sekvenca

SLC17A6
Identifikatori
Aliasi	SLC17A6
Vanjski ID-jevi	OMIM: 607563 MGI: 2156052 HomoloGene: 121617 GeneCards: SLC17A6
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek)[1] Bend 11p14.3 Početak 22,338,381 bp[1] Kraj 22,379,503 bp[1]
Lokacija gena (miš) Hrom. Hromosom 7 (miš)[2] Bend 7|7 B4 Početak 51,271,754 bp[2] Kraj 51,320,867 bp[2]
Ontologija gena Molekularna funkcija • symporter activity • L-glutamate transmembrane transporter activity • neurotransmitter transmembrane transporter activity Ćelijska komponenta • integral component of membrane • neuron projection • međućelijske veze • sinapsa • synaptic vesicle membrane • membrana • GO:0016023 citoplazmatska vezikula • integral component of synaptic vesicle membrane • excitatory synapse Biološki proces • neurotransmitter transport • ion transport • sodium ion transport • GO:0015915 transport • transmembrane transport • L-glutamate transmembrane transport • synaptic transmission, glutamatergic • regulation of synapse structure or activity • neurotransmitter loading into synaptic vesicle Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	57084	140919
Ensembl	ENSG00000091664	ENSMUSG00000030500
UniProt	Q9P2U8	Q8BLE7
RefSeq (mRNK)	NM_020346	NM_080853 NM_001355150
RefSeq (bjelančevina)	NP_065079	NP_543129 NP_001342079
Lokacija (UCSC)	Chr 11: 22.34 – 22.38 Mb	Chr 7: 51.27 – 51.32 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Dužina polipeptidnog lanca je 582 aminokiseline, а molekulska težina 64.392 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MESVKQRILA		PGKEGLKNFA		GKSLGQIYRV		LEKKQDTGET		IELTEDGKPL
EVPERKAPLC		DCTCFGLPRR		YIIAIMSGLG		FCISFGIRCN		LGVAIVDMVN
NSTIHRGGKV		IKEKAKFNWD		PETVGMIHGS		FFWGYIITQI		PGGYIASRLA
ANRVFGAAIL		LTSTLNMLIP		SAARVHYGCV		IFVRILQGLV		EGVTYPACHG
IWSKWAPPLE		RSRLATTSFC		GSYAGAVIAM		PLAGILVQYT		GWSSVFYVYG
SFGMVWYMFW		LLVSYESPAK		HPTITDEERR		YIEESIGESA		NLLGAMEKFK
TPWRKFFTSM		PVYAIIVANF		CRSWTFYLLL		ISQPAYFEEV		FGFEISKVGM
LSAVPHLVMT		IIVPIGGQIA		DFLRSKQILS		TTTVRKIMNC		GGFGMEATLL
LVVGYSHTRG		VAISFLVLAV		GFSGFAISGF		NVNHLDIAPR		YASILMGISN
GVGTLSGMVC		PIIVGAMTKN		KSREEWQYVF		LIAALVHYGG		VIFYAIFASG
EKQPWADPEE		TSEEKCGFIH		EDELDEETGD		ITQNYINYGT		TKSYGATTQA
NGGWPSGWEK		KEEFVQGEVQ		DSHSYKDRVD		YS

Reference

1. GRCh38: Ensembl release 89: ENSG00000091664 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030500 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Solute carrier family 17 (vesicular glutamate transporter), member 6". Pristupljeno 2. 2. 2016.
6. "UniProt, Q9P2U8". Pristupljeno 27. 8. 2021.