MAL-liki protein jest protein koji je kod ljudi kodiran genom MALL sa hromosoma 2.[5][6]
Kratke činjenice Identifikatori, Aliasi ...
Zatvori
Dužina polipeptidnog lanca je 153 aminokiseline, a molekulska težina 17.350 Da.[7]
10 | | 20 | | 30 | | 40 | | 50 |
MASPDPPATS | | YAPSDVPSGV | | ALFLTIPFAF | | FLPELIFGFL | | VWTMVAATHI |
VYPLLQGWVM | | YVSLTSFLIS | | LMFLLSYLFG | | FYKRFESWRV | | LDSLYHGTTG |
ILYMSAAVLQ | | VHATIVSEKL | | LDPRIYYINS | | AASFFAFIAT | | LLYILHAFSI |
YYH |
Ovaj gen kodira element mehanizma za promet endotelnih ćelija posredovan premosnicom. Kodirani protein, član porodice proteolipida MAL, nalazi se pretežno u membranama obogaćenim glikolipidima i holesterolom (GEM). U interakciji je sa kaveolinom-1.[6]
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- Kurdina MI, Denisov LE (1993). "[An evaluation of the efficacy of dispensary care as a method for the active detection of skin melanoma]". Klinicheskaia Meditsina. 70 (11–12): 68–70. PMID 1294831.
- Lautner-Rieske A, Thiebe R, Zachau HG (1995). "Searching for non-V kappa transcripts from the human immunoglobulin kappa locus". Gene. 159 (2): 199–202. doi:10.1016/0378-1119(95)00161-X. PMID 7622049.
- Saunier S, Calado J, Heilig R, et al. (1998). "A novel gene that encodes a protein with a putative src homology 3 domain is a candidate gene for familial juvenile nephronophthisis". Hum. Mol. Genet. 6 (13): 2317–23. doi:10.1093/hmg/6.13.2317. PMID 9361039.
- de Marco MC, Kremer L, Albar JP, et al. (2001). "BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells". J. Biol. Chem. 276 (25): 23009–17. doi:10.1074/jbc.M009739200. PMID 11294831.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.