Protein 2 sa PERQ aminokiselinski bogatim domenom GYF jest protein koji je kod ljudi kodiran genom GIGYF2 sa hromosoma 2.[5][6][7][8][9]
Kratke činjenice Identifikatori, Aliasi ...
Zatvori
Dužina polipeptidnog lanca je 1.299 aminokiselina, a molekulska težina 150.070 Da.[10]
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MAAETQTLNF | | GPEWLRALSS | | GGSITSPPLS | | PALPKYKLAD | | YRYGREEMLA |
LFLKDNKIPS | | DLLDKEFLPI | | LQEEPLPPLA | | LVPFTEEEQR | | NFSMSVNSAA |
VLRLTGRGGG | | GTVVGAPRGR | | SSSRGRGRGR | | GECGFYQRSF | | DEVEGVFGRG |
GGREMHRSQS | | WEERGDRRFE | | KPGRKDVGRP | | NFEEGGPTSV | | GRKHEFIRSE |
SENWRIFREE | | QNGEDEDGGW | | RLAGSRRDGE | | RWRPHSPDGP | | RSAGWREHME |
RRRRFEFDFR | | DRDDERGYRR | | VRSGSGSIDD | | DRDSLPEWCL | | EDAEEEMGTF |
DSSGAFLSLK | | KVQKEPIPEE | | QEMDFRPVDE | | GEECSDSEGS | | HNEEAKEPDK |
TNKKEGEKTD | | RVGVEASEET | | PQTSSSSARP | | GTPSDHQSQE | | ASQFERKDEP |
KTEQTEKAEE | | ETRMENSLPA | | KVPSRGDEMV | | ADVQQPLSQI | | PSDTASPLLI |
LPPPVPNPSP | | TLRPVETPVV | | GAPGMGSVST | | EPDDEEGLKH | | LEQQAEKMVA |
YLQDSALDDE | | RLASKLQEHR | | AKGVSIPLMH | | EAMQKWYYKD | | PQGEIQGPFN |
NQEMAEWFQA | | GYFTMSLLVK | | RACDESFQPL | | GDIMKMWGRV | | PFSPGPAPPP |
HMGELDQERL | | TRQQELTALY | | QMQHLQYQQF | | LIQQQYAQVL | | AQQQKAALSS |
QQQQQLALLL | | QQFQTLKMRI | | SDQNIIPSVT | | RSVSVPDTGS | | IWELQPTASQ |
PTVWEGGSVW | | DLPLDTTTPG | | PALEQLQQLE | | KAKAAKLEQE | | RREAEMRAKR |
EEEERKRQEE | | LRRQQEEILR | | RQQEEERKRR | | EEEELARRKQ | | EEALRRQREQ |
EIALRRQREE | | EERQQQEEAL | | RRLEERRREE | | EERRKQEELL | | RKQEEEAAKW |
AREEEEAQRR | | LEENRLRMEE | | EAARLRHEEE | | ERKRKELEVQ | | RQKELMRQRQ |
QQQEALRRLQ | | QQQQQQQLAQ | | MKLPSSSTWG | | QQSNTTACQS | | QATLSLAEIQ |
KLEEERERQL | | REEQRRQQRE | | LMKALQQQQQ | | QQQQKLSGWG | | NVSKPSGTTK |
SLLEIQQEEA | | RQMQKQQQQQ | | QQHQQPNRAR | | NNTHSNLHTS | | IGNSVWGSIN |
TGPPNQWASD | | LVSSIWSNAD | | TKNSNMGFWD | | DAVKEVGPRN | | STNKNKNNAS |
LSKSVGVSNR | | QNKKVEEEEK | | LLKLFQGVNK | | AQDGFTQWCE | | QMLHALNTAN |
NLDVPTFVSF | | LKEVESPYEV | | HDYIRAYLGD | | TSEAKEFAKQ | | FLERRAKQKA |
NQQRQQQQLP | | QQQQQQPPQQ | | PPQQPQQQDS | | VWGMNHSTLH | | SVFQTNQSNN |
QQSNFEAVQS | | GKKKKKQKMV | | RADPSLLGFS | | VNASSERLNM | | GEIETLDDY |
Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). "cDNAs with long CAG trinucleotide repeats from human brain". Hum Genet. 100 (1): 114–22. doi:10.1007/s004390050476. PMID 9225980. S2CID 25999127.
- Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Kofler M, Motzny K, Freund C (2006). "GYF domain proteomics reveals interaction sites in known and novel target proteins". Mol. Cell. Proteomics. 4 (11): 1797–811. doi:10.1074/mcp.M500129-MCP200. PMID 16120600.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.