Shugoshin-liki prorein 2 (S. pombe), znan I kao SGOL2, jest protein koji je kod ljudi kodiran genom SGOL2 jest protein koji je kod ljudi kodiran genom sa hromosoma 2.[5][6]
Kratke činjenice Identifikatori, Aliasi ...
Zatvori
Dužina polipeptidnog lanca je 1.265 aminokiselina, a molekulska težina 144.739 Da.[7]
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MECPVMETGS | | LFTSGIKRHL | | KDKRISKTTK | | LNVSLASKIK | | TKILNNSSIF |
KISLKHNNRA | | LAQALSREKE | | NSRRITTEKM | | LLQKEVEKLN | | FENTFLRLKL |
NNLNKKLIDI | | EALMNNNLIT | | AIEMSSLSEF | | HQSSFLLSAS | | KKKRISKQCK |
LMRLPFARVP | | LTSNDDEDED | | KEKMQCDNNI | | KSKTLPDIPS | | SGSTTQPLST |
QDNSEVLFLK | | ENNQNVYGLD | | DSEHISSIVD | | VPPRESHSHS | | DQSSKTSLMS |
EMRNAQSIGR | | RWEKPSPSNV | | TERKKRGSSW | | ESNNLSADTP | | CATVLDKQHI |
SSPELNCNNE | | INGHTNETNT | | EMQRNKQDLP | | GLSSESAREP | | NAECMNQIED |
NDDFQLQKTV | | YDADMDLTAS | | EVSKIVTVST | | GIKKKSNKKT | | NEHGMKTFRK |
VKDSSSEKKR | | ERSKRQFKNS | | SDVDIGEKIE | | NRTERSDVLD | | GKRGAEDPGF |
IFNNEQLAQM | | NEQLAQVNEL | | KKMTLQTGFE | | QGDRENVLCN | | KKEKRITNEQ |
EETYSLSQSS | | GKFHQESKFD | | KGQNSLTCNK | | SKASRQTFVI | | HKLEKDNLLP |
NQKDKVTIYE | | NLDVTNEFHT | | ANLSTKDNGN | | LCDYGTHNIL | | DLKKYVTDIQ |
PSEQNESNIN | | KLRKKVNRKT | | EIISGMNHMY | | EDNDKDVVHG | | LKKGNFFFKT |
QEDKEPISEN | | IEVSKELQIP | | ALSTRDNENQ | | CDYRTQNVLG | | LQKQITNMYP |
VQQNESKVNK | | KLRQKVNRKT | | EIISEVNHLD | | NDKSIEYTVK | | SHSLFLTQKD |
KEIIPGNLED | | PSEFETPALS | | TKDSGNLYDS | | EIQNVLGVKH | | GHDMQPACQN |
DSKIGKKPRL | | NVCQKSEIIP | | ETNQIYENDN | | KGVHDLEKDN | | FFSLTPKDKE |
TISENLQVTN | | EFQTVDLLIK | | DNGNLCDYDT | | QNILELKKYV | | TDRKSAEQNE |
SKINKLRNKV | | NWKTEIISEM | | NQIYEDNDKD | | AHVQESYTKD | | LDFKVNKSKQ |
KLECQDIINK | | HYMEVNSNEK | | ESCDQILDSY | | KVVKKRKKES | | SCKAKNILTK |
AKNKLASQLT | | ESSQTSISLE | | SDLKHITSEA | | DSDPGNPVEL | | CKTQKQSTTT |
LNKKDLPFVE | | EIKEGECQVK | | KVNKMTSKSK | | KRKTSIDPSP | | ESHEVMERIL |
DSVQGKSTVS | | EQADKENNLE | | NEKMVKNKPD | | FYTKAFRSLS | | EIHSPNIQDS |
SFDSVREGLV | | PLSVSSGKNV | | IIKENFALEC | | SPAFQVSDDE | | HEKMNKMKFK |
VNRRTQKSGI | | GDRPLQDLSN | | TSFVSNNTAE | | SENKSEDLSS | | ERTSRRRRCT |
PFYFKEPSLR | | DKMRR |
Shugoshin-liki protein 2 (SGOL2) je jedan od dva sisarska ortologa iz Shugoshin/Mei-S322 porodice proteina koji regulišu sestrinsku hromatidnunu koheziju zaštitom integriteta multiproteinskog kompleksa nazvanog kohezin.[8] Ovaj zaštitni sistem je neophodan za vjernu segregaciju hromosoma tokom mitoza i mejoza, što je fizička osnova Mendelovog nasljeđa.
Više informacija Svojstvo, Fenotip ...
Zatvori
- Svi testovi i analuitze su prema[11][12]
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- Hartley JL; Temple GF; Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Kitajima TS, Sakuno T, Ishiguro K, et al. (2006). "Shugoshin collaborates with protein phosphatase 2A to protect cohesin". Nature. 441 (7089): 46–52. Bibcode:2006Natur.441...46K. doi:10.1038/nature04663. PMID 16541025. S2CID 4425074.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.