Oleuropein je hemijsko jedinjenje pristno u maslinovom lišću. Ono se javlja zajedno sa blisko srodnim jedinjenjima kao što su 10-hidroksioleuropein, ligstrozid, i 10-hidroksiligstrozid. Sva ta jedinjenja su tirozolni estri elenolinske kiseline koja su dalje hidroksilovana i glikozilovana. On je jedan od glavnih prirodnih fenola prisutnih u arganskom ulju.[3] On je takođe prisutan u lišću kaline.
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Oleuropein i njegov metabolit hidroksitirozol imaju moćno antioksidansno dejstvo in vivo i in vitro. Oleuropein je jedno od jedinjenja koja daju ekstra devičanskom maslinovom ulju njegov gorak, opor ukus. Preparati oleuropeina imaju više farmakoloških dejstava,[4][5] jedno od kojih je ojačavanje imunskog sistema. Ispitivanja na pacovima sugerišu da oleuropein pojačava termogenezu putem povišenaj sadržaja termogenina u smeđem adipoznom tkivu i sekreciju noradrenalina i adrenalina.[6]
Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. Charrouf, Z.; Guillaume, D. (2007). „Phenols and Polyphenols from Argania spinosa”. American Journal of Food Technology. 2 (7): 679—683. doi:10.3923/ajft.2007.679.683. Sudjana, Aurelia N.; D’Orazio, Carla; Ryan, Vanessa; Rasool, Nooshin; Ng, Justin; Islam, Nabilah; Riley, Thomas V.; Hammer, Katherine A. (2009). „Antimicrobial activity of commercial Olea europaea (olive) leaf extract”. International Journal of Antimicrobial Agents. 33 (5): 461—3. PMID 19135874. doi:10.1016/j.ijantimicag.2008.10.026. Oi-Kano, Yuriko; Kawada, Teruo; Watanabe, Tatsuo; Koyama, Fumihiro; Watanabe, Kenichi; Senbongi, Reijirou; Iwai, Kazuo (2008). „Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats”. Journal of Nutritional Science and Vitaminology. 54 (5): 363—70. PMID 19001767. doi:10.3177/jnsv.54.363.
- Tripoli, Elisa; Giammanco, Marco; Tabacchi, Garden; Di Majo, Danila; Giammanco, Santo; La Guardia, Maurizio (2009). „The phenolic compounds of olive oil: Structure, biological activity and beneficial effects on human health”. Nutrition Research Reviews. 18 (1): 98—112. PMID 19079898. S2CID 221216561. doi:10.1079/NRR200495.
- Walter Jr, WM; Fleming, HP; Etchells, JL (1973). „Preparation of antimicrobial compounds by hydrolysis of oleuropein from green olives”. Applied Microbiology. 26 (5): 773—6. PMC 379900
. PMID 4762396. doi:10.1128/am.26.5.773-776.1973.
- Andreadou, Ioanna; Iliodromitis, Efstathios K.; Mikros, Emmanuel; Constantinou, Maria; Agalias, Apostolos; Magiatis, Prokopios; Skaltsounis, Alexios Leandros; Kamber, Elli; Tsantili-Kakoulidou, Anna (2006). „The Olive Constituent Oleuropein Exhibits Anti-Ischemic, Antioxidative, and Hypolipidemic Effects in Anesthetized Rabbits”. The Journal of Nutrition. 136 (8): 2213—9. PMID 16857843. doi:10.1093/jn/136.8.2213.
- Leehuang, S; Huang, P; Zhang, D; Lee, J; Bao, J; Sun, Y; Chang, Y; Zhang, J; Huang, P (2007). „Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition”. Biochemical and Biophysical Research Communications. 354 (4): 872—8. PMC 2790717 . PMID 17275783. doi:10.1016/j.bbrc.2007.01.071.
- Lee-Huang S, Huang P, Huang P (11 July 2004—16). „Anti-HIV activity of olive leaf extract and synergism with HAART”. Int Conf AIDS 15th. Bangkok.
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