TCF19

TCF19
Identifikatori
Aliasi	TCF19
Vanjski ID-jevi	OMIM: 600912 MGI: 103180 HomoloGene: 5156 GeneCards: TCF19
Lokacija gena (čovjek)
Hrom.	Hromosom 6 (čovjek)
Kraj	31,167,159 bp
Lokacija gena (miš)
Hrom.	Hromosom 17 (miš)
Kraj	35,827,721 bp
Ontologija gena
Molekularna funkcija	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • vezivanje iona metala; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• jedro;
Biološki proces	• transcription, DNA-templated; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II; • Ćelijska proliferacija; • GO:0009373 regulation of transcription, DNA-templated;
	Izvori:Amigo / QuickGO
Ortolozi
	6941
	106795
ENSG00000233890; ENSG00000224472; ENSG00000137310; ENSG00000224941; ENSG00000234674;
	ENSG00000206455; ENSG00000224379
	ENSMUSG00000050410
	Q9Y242
	Q99KJ5
	NM_001077511; NM_007109; NM_001318908
	NM_001163763; NM_001163764; NM_025674
	NP_001070979; NP_001305837; NP_009040
	NP_001157235; NP_001157236; NP_079950
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Transkripcijski faktor 19 jest protein koji je kod ljudi kodiran genom TCF19.^[5]^[6]^[7]

Kratke činjenice Identifikatori, Aliasi ...

Zatvori

Dužina polipeptidnog lanca je 345 aminokiselina, а molekulska težina 37.184 Da.^[8]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MLPCFQLLRI	GGGRGGDLYT	FHPPAGAGCT	YRLGHRADLC	DVALRPQQEP
GLISGIHAEL	HAEPRGDDWR	VSLEDHSSQG	TLVNNVRLPR	GHRLELSDGD
LLTFGPEGPP	GTSPSEFYFM	FQQVRVKPQD	FAAITIPRSR	GEARVGAGFR
PMLPSQGAPQ	RPLSTFSPAP	KATLILNSIG	SLSKLRPQPL	TFSPSWGGPK
SLPVPAPPGE	MGTTPSAPPQ	RNRRKSVHRV	LAELDDESEP	PENPPPVLME
PRKKLRVDKA	PLTPTGNRRG	RPRKYPVSAP	MAPPAVGGGE	PCAAPCCCLP
QEETVAWVQC	DGCDVWFHVA	CVGCSIQAAR	EADFRCPGCR	AGIQT

[1]
ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 GRCh38: Ensembl release 89: ENSG00000233890, ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 - Ensembl, maj 2017
[2]
GRCm38: Ensembl release 89: ENSMUSG00000050410 - Ensembl, maj 2017
[3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[5]
Ku DH, Chang CD, Koniecki J, Cannizzaro LA, Boghosian-Sell L, Alder H, Baserga R (Sep 1991). "A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor". Cell Growth Differ. 2 (4): 179–86. PMID 1868030.
[6]
Krishnan BR, Jamry I, Chaplin DD (Apr 1996). "Feature mapping of the HLA class I region: localization of the POU5F1 and TCF19 genes". Genomics. 30 (1): 53–8. doi:10.1006/geno.1995.0008. PMID 8595903.
[7]
"Entrez Gene: TCF19 transcription factor 19 (SC1)".
[8]
"UniProt, Q9Y242" (jezik: engleski). Pristupljeno 5. 10. 2021.

Teraoka Y, Naruse TK, Oka A, et al. (2000). "Genetic polymorphisms in the cell growth regulated gene, SC1 telomeric of the HLA-C gene and lack of association of psoriasis vulgaris". Tissue Antigens. 55 (3): 206–11. doi:10.1034/j.1399-0039.2000.550303.x. PMID 10777095.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Shiina T, Ota M, Shimizu S, et al. (2006). "Rapid Evolution of Major Histocompatibility Complex Class I Genes in Primates Generates New Disease Alleles in Humans via Hitchhiking Diversity". Genetics. 173 (3): 1555–70. doi:10.1534/genetics.106.057034. PMC 1526686. PMID 16702430.

[refGRCh38Ensembl-1] [1]
ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 GRCh38: Ensembl release 89: ENSG00000233890, ENSG00000224472, ENSG00000137310, ENSG00000224941, ENSG00000234674, ENSG00000206455, ENSG00000224379 - Ensembl, maj 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000050410 - Ensembl, maj 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1868030-5] [5]
Ku DH, Chang CD, Koniecki J, Cannizzaro LA, Boghosian-Sell L, Alder H, Baserga R (Sep 1991). "A new growth-regulated complementary DNA with the sequence of a putative trans-activating factor". Cell Growth Differ. 2 (4): 179–86. PMID 1868030.

[pmid8595903-6] [6]
Krishnan BR, Jamry I, Chaplin DD (Apr 1996). "Feature mapping of the HLA class I region: localization of the POU5F1 and TCF19 genes". Genomics. 30 (1): 53–8. doi:10.1006/geno.1995.0008. PMID 8595903.

[entrez-7] [7]
"Entrez Gene: TCF19 transcription factor 19 (SC1)".

[UniProt-8] [8]
"UniProt, Q9Y242" (jezik: engleski). Pristupljeno 5. 10. 2021.

[5]

[6]

[7]

[1]

[2]

[3]

[4]

[8]

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TCF19

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Aminokiselinska sekvenca

Reference

Dopunska literatura