SATB2

SPATS2-liki protein (spermatogenezi pridruženi, serin-bogati 2-liki protein) ili DNAPTP6 (DNK-polimerazno transaktivirtani protein 6) jest protein koji je kod ljudi kodiran genom SPATS2L sa hromosoma 2..^[5][6]

SATB2
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 1WI3, 1WIZ, 2CSF
Identifikatori
Aliasi	SATB2
Vanjski ID-jevi	OMIM: 608148 MGI: 2679336 HomoloGene: 32249 GeneCards: SATB2
Lokacija gena (čovjek) Hrom. Hromosom 2 (čovjek)[1] Bend 2q33.1 Početak 199,269,500 bp[1] Kraj 199,471,266 bp[1]
Lokacija gena (miš) Hrom. Hromosom 1 (miš)[2] Bend 1|1 C1.3 Početak 56,833,140 bp[2] Kraj 57,017,809 bp[2]
Ontologija gena Molekularna funkcija • sequence-specific DNA binding • vezivanje sa DNK • chromatin binding • GO:0001948, GO:0016582 vezivanje za proteine • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • histone deacetylase complex • transcription regulator complex • nuclear matrix • jedro • nukleoplazma Biološki proces • commitment of neuronal cell to specific neuron type in forebrain • embryonic skeletal system morphogenesis • cellular response to organic substance • chromatin remodeling • roof of mouth development • GO:0009373 regulation of transcription, DNA-templated • embryonic pattern specification • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • neuron migration • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • multicellular organism development • cartilage development • Regulacija ekspresije gena • osteoblast development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	23314	212712
Ensembl	ENSG00000119042	ENSMUSG00000038331
UniProt	Q9UPW6	Q8VI24
RefSeq (mRNK)	NM_001172509 NM_001172517 NM_015265	NM_139146 NM_001358580 NM_001358581
RefSeq (bjelančevina)	NP_001165980 NP_001165988 NP_056080	NP_631885 NP_001345509 NP_001345510
Lokacija (UCSC)	Chr 2: 199.27 – 199.47 Mb	Chr 1: 56.83 – 57.02 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 558 aminokiselina, a molekulska težina 6 729 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAELNTHVNV		KEKIYAVRSV		VPNKSNNEIV		LVLQQFDFNV		DKAVQAFVDG
SAIQVLKEWN		MTGKKKNNKR		KRSKSKQHQG		NKDAKDKVER		PEAGPLQPQP
PQIQNGPMNG		CEKDSSSTDS		ANEKPALIPR		EKKISILEEP		SKALRGVTEG
NRLLQQKLSL		DGNPKPIHGT		TERSDGLQWS		AEQPCNPSKP		KAKTSPVKSN
TPAAHLEIKP		DELAKKRGPN		IEKSVKDLQR		CTVSLTRYRV		MIKEEVDSSV
KKIKAAFAEL		HNCIIDKEVS		LMAEMDKVKE		EAMEILTARQ		KKAEELKRLT
DLASQMAEMQ		LAELRAEIKH		FVSERKYDEE		LGKAARFSCD		IEQLKAQIML
CGEITHPKNN		YSSRTPCSSL		LPLLNAHAAT		SGKQSNFSRK		SSTHNKPSEG
KAANPKMVSS		LPSTADPSHQ		TMPANKQNGS		SNQRRRFNPQ		YHNNRLNGPA
KSQGSGNEAE		PLGKGNSRHE		HRRQPHNGFR		PKNKGGAKNQ		EASLGMKTPE
APAHSEKPRR		RQHAADTSEA		RPFRGSVGRV		SQCNLCPTRI		EVSTDAAVLS
VPAVTLVA