RNF183

Ringoprstni protein 183 je protein koji je kod ljudi kodiran genom RNF183.^[5]

RNF183
Identifikatori
Aliasi	RNF183
Vanjski ID-jevi	MGI: 1923322 HomoloGene: 44917 GeneCards: RNF183
Lokacija gena (čovjek) Hrom. Hromosom 9 (čovjek)[1] Bend 9q32 Početak 113,297,093 bp[1] Kraj 113,303,376 bp[1]
Lokacija gena (miš) Hrom. Hromosom 4 (miš)[2] Bend 4|4 B3 Početak 62,345,777 bp[2] Kraj 62,353,489 bp[2]
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • vezivanje iona metala • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • aktivnost sa transferazom Ćelijska komponenta • membrana • integral component of membrane • Endoplazmatski retikulum • Lizozom • lysosomal membrane • endoplasmic reticulum membrane • Golđijev aparat • integral component of endoplasmic reticulum membrane • cis-Golgi network membrane Biološki proces • protein polyubiquitination • protein ubiquitination • GO:0097285 apoptoza • response to endoplasmic reticulum stress • protein autoubiquitination • positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	138065	76072
Ensembl	ENSG00000165188	ENSMUSG00000063851
UniProt	Q96D59	Q8QZS5
RefSeq (mRNK)	NM_145051 NM_001371234 NM_001371235 NM_001371236 NM_001371237 NM_001387568 NM_001387569	NM_153504 NM_001379623 NM_001379624 NM_001379625
RefSeq (bjelančevina)	NP_659488 NP_001358163 NP_001358164 NP_001358165 NP_001358166	NP_705724 NP_001366552 NP_001366553 NP_001366554
Lokacija (UCSC)	Chr 9: 113.3 – 113.3 Mb	Chr 4: 62.35 – 62.35 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 192 aminokiseline, а molekulska težina 21.617 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAEQQGRELE		AECPVCWNPF		NNTFHTPKML		DCCHSFCVEC		LAHLSLVTPA
RRRLLCPLCR		QPTVLASGQP		VTDLPTDTAM		LALLRLEPHH		VILEGHQLCL
KDQPKSRYFL		RQPQVYTLDL		GPQPGGQTGP		PPDTASATVS		TPILIPSHHS
LRECFRNPQF		RIFAYLMAVI		LSVTLLLIFS		IFWTKQFLWG		VG

Reference

1. GRCh38: Ensembl release 89: ENSG00000165188 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000063851 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Ring finger protein 183". Pristupljeno 4. 3. 2013.
6. "UniProt, Q96D59". Pristupljeno 11. 9. 2021.