Glukozamin-6-fosfat izomeraza 1 jest enzim koji je kod ljudi kodiran genom GNPDA1 sa hromosoma 5.[5][6][7]
Kratke činjenice Dostupne strukture, PDB ...
Zatvori
Dužina polipeptidnog lanca je 289 aminokiselina, а molekulska težina 32.669 Da.[8]
| 10 | | 20 | | 30 | | 40 | | 50 |
|---|
| MKLIILEHYS | | QASEWAAKYI | | RNRIIQFNPG | | PEKYFTLGLP | | TGSTPLGCYK |
| KLIEYYKNGD | | LSFKYVKTFN | | MDEYVGLPRD | | HPESYHSFMW | | NNFFKHIDIH |
| PENTHILDGN | | AVDLQAECDA | | FEEKIKAAGG | | IELFVGGIGP | | DGHIAFNEPG |
| SSLVSRTRVK | | TLAMDTILAN | | ARFFDGELTK | | VPTMALTVGV | | GTVMDAREVM |
| ILITGAHKAF | | ALYKAIEEGV | | NHMWTVSAFQ | | QHPRTVFVCD | | EDATLELKVK |
| TVKYFKGLML | | VHNKLVDPLY | | SIKEKETEKS | | QSSKKPYSD |
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- Weidanz JA, Campbell P, DeLucas LJ, et al. (1995). "Glucosamine 6-phosphate deaminase in normal human erythrocytes". Br. J. Haematol. 91 (1): 72–9. doi:10.1111/j.1365-2141.1995.tb05247.x. PMID 7577655. S2CID 31559803.
- Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 1 (5): 223–9. doi:10.1093/dnares/1.5.223. PMID 7584044.
- Oliva G, Fontes MR, Garratt RC, et al. (1996). "Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 A resolution". Structure. 3 (12): 1323–32. doi:10.1016/S0969-2126(01)00270-2. hdl:11449/64662. PMID 8747459.
- Nakamura Y, Miura K, Fujino Y, et al. (2001). "Evolution, structure, and expression of GNPI/Oscillin orthologous genes". Genomics. 68 (2): 179–86. doi:10.1006/geno.2000.6287. PMID 10964516.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Zhang J, Zhang W, Zou D, et al. (2003). "Cloning and functional characterization of GNPI2, a novel human homolog of glucosamine-6-phosphate isomerase/oscillin". J. Cell. Biochem. 88 (5): 932–40. doi:10.1002/jcb.10444. PMID 12616532. S2CID 24448482.
- Arreola R, Valderrama B, Morante ML, Horjales E (2003). "Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study". FEBS Lett. 551 (1–3): 63–70. doi:10.1016/S0014-5793(03)00896-2. PMID 12965206. S2CID 45050024.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Schmutz J, Martin J, Terry A, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 5". Nature. 431 (7006): 268–74. Bibcode:2004Natur.431..268S. doi:10.1038/nature02919. PMID 15372022.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
GNPDA1 detalji ljudskog genoma u UCSC Genome Browser.
