ZDHHC14

Cinkov prst tipa DHHC sa proteinom 14 jest protein koji je kod ljudi kodiran genom ZDHHC14.^[5]

ZDHHC14
Identifikatori
Aliasi	ZDHHC14
Vanjski ID-jevi	MGI: 2653229 HomoloGene: 62301 GeneCards: ZDHHC14
Lokacija gena (čovjek) Hrom. Hromosom 6 (čovjek)[1] Bend 6q25.3 Početak 157,381,133 bp[1] Kraj 157,678,157 bp[1]
Lokacija gena (miš) Hrom. Hromosom 17 (miš)[2] Bend 17|17 A1 Početak 5,542,832 bp[2] Kraj 5,804,086 bp[2]
Ontologija gena Molekularna funkcija • protein-cysteine S-palmitoyltransferase activity • GO:0019105, GO:0018010 palmitoyltransferase activity • aktivnost sa transferazom • acyltransferase activity Ćelijska komponenta • integral component of membrane • Endoplazmatski retikulum • membrana • Golđijev aparat Biološki proces • protein palmitoylation • protein targeting to membrane • peptidyl-L-cysteine S-palmitoylation Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	79683	224454
Ensembl	ENSG00000175048	ENSMUSG00000034265
UniProt	Q8IZN3	Q8BQQ1
RefSeq (mRNK)	NM_024630 NM_153746	NM_146073
RefSeq (bjelančevina)	NP_078906 NP_714968	NP_666185
Lokacija (UCSC)	Chr 6: 157.38 – 157.68 Mb	Chr 17: 5.54 – 5.8 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 488 aminokiselina, а molekulska težina 53.388 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MPPGGGGPMK		DCEYSQISTH		SSSPMESPHK		KKKIAARRKW		EVFPGRNKFF
CNGRIMMARQ		TGVFYLTLVL		ILVTSGLFFA		FDCPYLAVKI		TPAIPAVAGI
LFFFVMGTLL		RTSFSDPGVL		PRATPDEAAD		LERQIDIANG		TSSGGYRPPP
RTKEVIINGQ		TVKLKYCFTC		KIFRPPRASH		CSLCDNCVER		FDHHCPWVGN
CVGKRNYRFF		YMFILSLSFL		TVFIFAFVIT		HVILRSQQTG		FLNALKDSPA
SVLEAVVCFF		SVWSIVGLSG		FHTYLISSNQ		TTNEDIKGSW		SNKRGKENYN
PYSYGNIFTN		CCVALCGPIS		PSLIDRRGYI		QPDTPQPAAP		SNGITMYGAT
QSQSDMCDQD		QCIQSTKFVL		QAAATPLLQS		EPSLTSDELH		LPGKPGLGTP
CASLTLGPPT		PPASMPNLAE		ATLADVMPRK		DEHMGHQFLT		PDEAPSPPRL
LAAGSPLAHS		RTMHVLGLAS		QDSLHEDSVR		GLVKLSSV

Reference

1. GRCh38: Ensembl release 89: ENSG00000175048 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034265 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger, DHHC-type containing 14".
6. "UniProt, Q8IZN3" (jezik: engleski). Pristupljeno 4. 10. 2021.

Dopunska literatura

• Clark SL, Adkins DE, Aberg K, Hettema JM, McClay JL, Souza RP, van den Oord EJ (juni 2012). "Pharmacogenomic study of side-effects for antidepressant treatment options in STAR*D". Psychological Medicine. 42 (6): 1151–62. doi:10.1017/S003329171100239X. PMC 3627503. PMID 22041458.