ZC2HC1

Protein 1B sa cinkovim prstom tipa C2HC jest protein koji je kod ljudi kodiran genom ZC2HC1B.^[5]

ZC2HC1
Identifikatori
Aliasi	ZC2HC1B
Vanjski ID-jevi	MGI: 1922372 HomoloGene: 77965 GeneCards: ZC2HC1B
Lokacija gena (čovjek) Hrom. Hromosom 6 (čovjek)[1] Bend 6q24.2 Početak 143,864,436 bp[1] Kraj 143,938,343 bp[1]
Lokacija gena (miš) Hrom. Hromosom 10 (miš)[2] Bend 10|10 A2 Početak 13,025,284 bp[2] Kraj 13,053,767 bp[2]
Ortolozi
Vrste	Čovjek	Miš
Entrez	153918	75122
Ensembl	ENSG00000118491	ENSMUSG00000019815
UniProt	Q5TFG8	Q9D534
RefSeq (mRNK)	NM_001013623	NM_029172
RefSeq (bjelančevina)	NP_001013645	NP_083448
Lokacija (UCSC)	Chr 6: 143.86 – 143.94 Mb	Chr 10: 13.03 – 13.05 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 222 aminokiseline, а molekulska težina 24.665 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAGAEPFLAD		GNQELFPCEV		CGRRFAADVL		ERHGPICKKL		FNRKRKPFSS
LKQRLQGTDI		PTVKKTPQSK		SPPVRKSNWR		QQHEDFINAI		RSAKQCMLAI
KEGRPLPPPP		PPSLNPDYIQ		RPYCMRRFNE		SAAERHTNFC		KDQSSRRVFN
PAQTAAKLAS		RAQGRAQMGP		KKEPTVTSAV		GALLQNRVLV		ATNEVPTKSG
LAMDPASGAK		LRQGFSKSSK		KD

Reference

1. GRCh38: Ensembl release 89: ENSG00000118491 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000019815 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Zinc finger C2HC-type containing 1B". Pristupljeno 31. 5. 2016.
6. "UniProt, Q5TFG8" (jezik: engleski). Pristupljeno 4. 10. 2021.

Dopunska literatura

• Prigge JR, Schmidt EE (2006). "Interaction of Protein Inhibitor of Activated STAT (PIAS) Proteins with the TATA-binding Protein, TBP". J. Biol. Chem. 281 (18): 12260–9. doi:10.1074/jbc.M510835200. PMC 2030495. PMID 16522640.
• Zheng G, Yang YC (2006). "Acetylation and alternative splicing regulate ZNF76-mediated transcription". Biochem. Biophys. Res. Commun. 339 (4): 1069–75. doi:10.1016/j.bbrc.2005.11.122. PMID 16337145.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Zheng G, Yang YC (2004). "ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation". J. Biol. Chem. 279 (41): 42410–21. doi:10.1074/jbc.M407287200. PMID 15280358.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Myslinski E, Krol A, Carbon P (1998). "ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf". J. Biol. Chem. 273 (34): 21998–2006. doi:10.1074/jbc.273.34.21998. PMID 9705341.