NRBF2

Jedarni receptor-vezujući faktor 2 je protein koji je kod ljudi kodiran genom NRBF2.^[5][6]

NRBF2
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 4ZEY
Identifikatori
Aliasi	NRBF2
Vanjski ID-jevi	OMIM: 616477 MGI: 1354950 HomoloGene: 41473 GeneCards: NRBF2
Lokacija gena (čovjek) Hrom. Hromosom 10 (čovjek)[1] Bend 10q21.3 Početak 63,133,247 bp[1] Kraj 63,155,031 bp[1]
Lokacija gena (miš) Hrom. Hromosom 10 (miš)[2] Bend 10|10 B5.1 Početak 67,102,468 bp[2] Kraj 67,121,084 bp[2]
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citoplazma • phosphatidylinositol 3-kinase complex, class III • Autofagosom • jedro • nukleoplazma • GO:0016023 citoplazmatska vezikula Biološki proces • transcription initiation from RNA polymerase II promoter • GO:0009373 regulation of transcription, DNA-templated • response to endoplasmic reticulum stress • transcription, DNA-templated • regulation of lipid kinase activity • Autofagija Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	29982	641340
Ensembl	ENSG00000148572	ENSMUSG00000075000
UniProt	Q96F24	Q8VCQ3
RefSeq (mRNK)	NM_001282405 NM_030759	NM_001036293
RefSeq (bjelančevina)	NP_001269334 NP_110386	NP_001031370 NP_001388976 NP_001388977
Lokacija (UCSC)	Chr 10: 63.13 – 63.16 Mb	Chr 10: 67.1 – 67.12 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 287 aminokiselina, a molekulska težina 32.378 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MEVMEGPLNL		AHQQSRRADR		LLAAGKYEEA		ISCHKKAAAY		LSEAMKLTQS
EQAHLSLELQ		RDSHMKQLLL		IQERWKRAQR		EERLKAQQNT		DKDAAAHLQT
SHKPSAEDAE		GQSPLSQKYS		PSTEKCLPEI		QGIFDRDPDT		LLYLLQQKSE
PAEPCIGSKA		PKDDKTIIEE		QATKIADLKR		HVEFLVAENE		RLRKENKQLK
AEKARLLKGP		IEKELDVDAD		FVETSELWSL		PPHAETATAS		STWQKFAANT
GKAKDIPIPN		LPPLDFPSPE		LPLMELSEDI		LKGFMNN

Reference

1. GRCh38: Ensembl release 89: ENSG00000148572 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075000 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yasumo H, Masuda N, Furusawa T, Tsukamoto T, Sadano H, Osumi T (maj 2000). "Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors". Biochim Biophys Acta. 1490 (1–2): 189–97. doi:10.1016/S0167-4781(99)00244-4. PMID 10786636.
6. "Entrez Gene: NRBF2 nuclear receptor binding factor 2".
7. "UniProt, Q96F24". Pristupljeno 3. 9. 2021.

Dopunska literatura

• Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Flores AM, Li L, Aneskievich BJ (2005). "Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator". J. Invest. Dermatol. 123 (6): 1092–101. doi:10.1111/j.0022-202X.2004.23424.x. PMID 15610520.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

Vanjski linkovi