IFT46

Homolog međuflagelskog transportnog proteina 46 je protein koji je kod ljudi kodiran genom IFT46.^[5][6][7]

IFT46
Identifikatori
Aliasi	IFT46
Vanjski ID-jevi	MGI: 1923818 HomoloGene: 10596 GeneCards: IFT46
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek)[1] Bend 11q23.3 Početak 118,544,528 bp[1] Kraj 118,572,970 bp[1]
Lokacija gena (miš) Hrom. Hromosom 9 (miš)[2] Bend 9|9 A5.2 Početak 44,679,205 bp[2] Kraj 44,704,744 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • protein C-terminus binding • molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citoplazma • intraciliary transport particle B • ciliary basal body • centrosom • projekcija ćelije • ciliary tip • citoskelet • Treplja • motile cilium Biološki proces • Ježev signalni put • protein stabilization • intraciliary transport • intraciliary transport involved in cilium assembly • cilium assembly • GO:0022610 biološki proces Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	56912	76568
Ensembl	ENSG00000118096	ENSMUSG00000002031
UniProt	Q9NQC8	Q9DB07
RefSeq (mRNK)	NM_001168618 NM_020153	NM_023831
RefSeq (bjelančevina)	NP_001162089 NP_064538	NP_076320
Lokacija (UCSC)	Chr 11: 118.54 – 118.57 Mb	Chr 9: 44.68 – 44.7 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 304 aminokiseline, a molekulska težina34.286 Da.^[8].

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MADNSSDECE		EENNKEKKKT		SQLTPQRGFS		ENEDDDDDDD		DSSETDSDSD
DDDEEHGAPL		EGAYDPADYE		HLPVSAEIKE		LFQYISRYTP		QLIDLDHKLK
PFIPDFIPAV		GDIDAFLKVP		RPDGKPDNLG		LLVLDEPSTK		QSDPTVLSLW
LTENSKQHNI		TQHMKVKSLE		DAEKNPKAID		TWIESISELH		RSKPPATVHY
TRPMPDIDTL		MQEWSPEFEE		LLGKVSLPTA		EIDCSLAEYI		DMICAILDIP
VYKSRIQSLH		LLFSLYSEFK		NSQHFKALAE		GKKAFTPSSN		STSQAGDMET
LTFS

Reference

1. GRCh38: Ensembl release 89: ENSG00000118096 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002031 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.
6. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
7. "Entrez Gene: C11orf60 chromosome 11 open reading frame 60".
8. "UniProt, Q9NQC8". Pristupljeno 23. 8. 2021.

Dopunska literatura

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.