GYLTL1B

GYLTL1B
Identifikatori
Aliasi	LARGE2
Vanjski ID-jevi	OMIM: 609709 MGI: 2443769 HomoloGene: 27362 GeneCards: LARGE2
Lokacija gena (čovjek)
Hrom.	Hromosom 11 (čovjek)
Kraj	45,929,096 bp
Lokacija gena (miš)
Hrom.	Hromosom 2 (miš)
Kraj	92,205,214 bp
Ontologija gena
Molekularna funkcija	• aktivnost sa transferazom; • catalytic activity; • manganese ion binding; • vezivanje iona metala; • xylosyltransferase activity; • glycosyltransferase activity; • UDP-xylosyltransferase activity; • glucuronosyltransferase activity; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• integral component of membrane; • Golđijev aparat; • membrana; • Golđijeva membrana;
Biološki proces	• GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation; • metabolizam; • protein O-linked mannosylation; • muscle cell cellular homeostasis; • protein O-linked glycosylation;
	Izvori:Amigo / QuickGO
Ortolozi
	120071
	228366
	ENSG00000165905
	ENSMUSG00000040434
	Q8N3Y3
	Q5XPT3
	NM_001300721; NM_001300722; NM_152312
	NM_001166633; NM_001290773; NM_001290774; NM_001290775; NM_172670
	NP_001287650; NP_001287651; NP_689525
	NP_001160105; NP_001277702; NP_001277703; NP_001277704; NP_766258
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Glikoziltransferazoliki protein LARGE2 je enzim koji je kod ljudi kodiran genom GYLTL1B.^[5]^[6]^[7]

Kratke činjenice Identifikatori, Aliasi ...

Zatvori

[1]
GRCh38: Ensembl release 89: ENSG00000165905 - Ensembl, maj 2017
[2]
GRCm38: Ensembl release 89: ENSMUSG00000040434 - Ensembl, maj 2017
[3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[5]
Brockington M, Torelli S, Prandini P, Boito C, Dolatshad NF, Longman C, Brown SC, Muntoni F (Feb 2005). "Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy". Hum Mol Genet. 14 (5): 657–65. doi:10.1093/hmg/ddi062. PMID 15661757.
[6]
Grewal PK, McLaughlan JM, Moore CJ, Browning CA, Hewitt JE (Sep 2005). "Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies". Glycobiology. 15 (10): 912–23. doi:10.1093/glycob/cwi094. PMID 15958417.
[7]
"Entrez Gene: GYLTL1B glycosyltransferase-like 1B".
[8]
"UniProt, Q8N3Y3". Pristupljeno 22. 8. 2021.

Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Fujimura K, Sawaki H, Sakai T, et al. (2005). "LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE". Biochem. Biophys. Res. Commun. 329 (3): 1162–71. doi:10.1016/j.bbrc.2005.02.082. PMID 15752776.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

Aminokiselinska sekvenca