GPRIN2

G-proteinom regulirani induktor neuritskog rasta 2 je protein koji je kod ljudi kodiran genom GPRIN2.^[5][6]

GPRIN2
Identifikatori
Aliasi	GPRIN2
Vanjski ID-jevi	OMIM: 611240 MGI: 2444560 HomoloGene: 40975 GeneCards: GPRIN2
Lokacija gena (čovjek) Hrom. Hromosom 10 (čovjek)[1] Bend 10q11.22 Početak 46,549,044 bp[1] Kraj 46,555,530 bp[1]
Lokacija gena (miš) Hrom. Hromosom 14 (miš)[2] Bend 14|14 B Početak 33,907,645 bp[2] Kraj 33,923,610 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ortolozi
Vrste	Čovjek	Miš
Entrez	9721	432839
Ensembl	ENSG00000204175	ENSMUSG00000071531
UniProt	O60269	D3Z1D7
RefSeq (mRNK)	NM_014696	NM_183209
RefSeq (bjelančevina)	NP_055511	NP_899032
Lokacija (UCSC)	Chr 10: 46.55 – 46.56 Mb	Chr 14: 33.91 – 33.92 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 458 aminokiselina, а molekulska težina 47 450 Da.^[7]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSSSRPEPGP		WAPLSPRLQP		LSQSSSSLLG		EGREQRPELR		KTASSTVWQA
QLGEASTRPQ		APEEEGNPPE		SMKPARASGP		KARPSAGGHW		WSSTVGNVST
MGGSDLCRLR		APSAAAMQRS		HSDLVRSTQM		RGHSGARKAS		LSCSALGSSP
VHRAQLQPGG		TSGQGGQAPA		GLERDLAPED		ETSNSAWMLG		ASQLSVPPLD
LGDTTAHSSS		AQAEPKAAEQ		LATTTCHALP		PAALLCGMRE		VRAGGCCHAL
PATGILAFPK		LVASVSESGL		QAQHGVKIHC		RLSGGLPGHS		HCCAHLWGPA
GLVPEPGSRT		KDVWTMTSAN		DLAPAEASPL		SAQDAGVQAA		PVAACKAVAT
SPSLEAPAAL		HVFPEVTLGS		SLEEVPSPVR		DVRWDAEGMT		WEVYGAAVDL
EVLGVAIQKH		LEMQFEQLQR		APASEDSLSV		EGRRGPLRAV		MQSLRRPSCC
GCSGAAPE

Reference

1. GRCh38: Ensembl release 89: ENSG00000204175 - Ensembl, maj 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000071531 - Ensembl, maj 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Ishikawa K, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Aug 1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
6. "Entrez Gene: GPRIN2 G protein regulated inducer of neurite outgrowth 2".
7. "UniProt, O60269". Pristupljeno 3. 9. 2021.

Dopunska literatura

• Chen LT, Gilman AG, Kozasa T (1999). "A candidate target for G protein action in brain". J. Biol. Chem. 274 (38): 26931–8. doi:10.1074/jbc.274.38.26931. PMID 10480904.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
• Iida N, Kozasa T (2005). "Identification and biochemical analysis of GRIN1 and GRIN2". u Siderovski DP (ured.). Regulators of G-Protein Signaling, Part B. Methods of Enzymology. 390. str. 475–83. doi:10.1016/S0076-6879(04)90029-8. ISBN 978-0-12-182795-3. PMID 15488195.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.