FAM213A

FAM213A
Identifikatori
Aliasi	PRXL2A
Vanjski ID-jevi	OMIM: 617165 MGI: 1917814 HomoloGene: 12356 GeneCards: PRXL2A
Lokacija gena (čovjek)
Hrom.	Hromosom 10 (čovjek)
Kraj	80,437,115 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	40,735,745 bp
Ontologija gena
Molekularna funkcija	• antioxidant activity;
Ćelijska komponenta	• citoplazma; • extracellular region;
Biološki proces	• regulation of osteoclast differentiation; • cellular oxidant detoxification;
	Izvori:Amigo / QuickGO
Ortolozi
	84293
	70564
	ENSG00000122378
	ENSMUSG00000021792
	Q9BRX8
	Q9CYH2
NM_001243778; NM_001243779; NM_001243780; NM_001243781; NM_001243782;
	NM_032333
NM_027464; NM_001316732; NM_001316733; NM_001316734; NM_001316735;
	NM_001316736; NM_001316737; NM_001316739; NM_001316740; NM_001378813; NM_001378814; NM_001378815
NP_001230707; NP_001230708; NP_001230709; NP_001230710; NP_001230711;
	NP_115709
NP_001303661; NP_001303662; NP_001303663; NP_001303664; NP_001303665;
	NP_001303666; NP_001303668; NP_001303669; NP_081740; NP_001365742; NP_001365743; NP_001365744
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Redoksregulacijski protein FAM213A, član A porodice proteina sa sličnošću sekvence 213A, znan i kao peroksiredoksinoliki protein 2 aktiviran M-CSF stimuliranim monocitima (PAMM) je protein koji je kod ljudi kodiran genom FAM213A.^[5]^[6]

Kratke činjenice Identifikatori, Aliasi ...

Zatvori

Dužina polipeptidnog lanca je 229 aminokiselina, а molekulska težina 25.764 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MSFLQDPSFF	TMGMWSIGAG	ALGAAALALL	LANTDVFLSK	PQKAALEYLE
DIDLKTLEKE	PRTFKAKELW	EKNGAVIMAV	RRPGCFLCRE	EAADLSSLKS
MLDQLGVPLY	AVVKEHIRTE	VKDFQPYFKG	EIFLDEKKKF	YGPQRRKMMF
MGFIRLGVWY	NFFRAWNGGF	SGNLEGEGFI	LGGVFVVGSG	KQGILLEHRE
KEFGDKVNLL	SVLEAAKMIK	PQTLASEKK

[1]
GRCh38: Ensembl release 89: ENSG00000122378 - Ensembl, maj 2017
[2]
GRCm38: Ensembl release 89: ENSMUSG00000021792 - Ensembl, maj 2017
[3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
[5]
Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
[6]
"Entrez Gene: C10orf58 chromosome 10 open reading frame 58".
[7]
"UniProt, Q9BRX8". Pristupljeno 1. 9. 2021.

Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000122378 - Ensembl, maj 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000021792 - Ensembl, maj 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11483580-5] [5]
Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.

[entrez-6] [6]
"Entrez Gene: C10orf58 chromosome 10 open reading frame 58".

[UniProt-7] [7]
"UniProt, Q9BRX8". Pristupljeno 1. 9. 2021.

[5]

[6]

[1]

[2]

[3]

[4]

[7]

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FAM213A

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Aminokiselinska sekvenca

Reference

Dopunska literatura