乌苏米施可汗（？—744年），突厥可汗，阙特勤之子。阿史那骨咄可汗被拔悉密、回纥、葛逻禄三部所杀，拔悉密酋长自立为颉跌伊施可汗。突厥余众共立乌苏米施可汗，唐玄宗想招降乌苏米施可汗，可汗不理，唐玄宗派朔方节度使王忠嗣联合拔悉密、回纥、葛逻禄三部攻击乌苏米施可汗，击溃。744年八月，乌苏米施可汗被拔悉密部所杀[1]。
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