雙腎上腺皮質激素樣激酶1(英語:Doublecortin like kinase 1,縮寫DCLK1)是一種絲氨酸/蘇氨酸激酶,在人類基因組中由DCLK1 基因編碼[6][7][8],在腸道上皮的叢細胞(Tuft cell)中大量表達,也是胃腸道腫瘤幹細胞的分子標誌物[9]。
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Omori Y, Suzuki M, Ozaki K, Harada Y, Nakamura Y, Takahashi E, Fujiwara T. Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin. J Hum Genet. Oct 1998, 43 (3): 169–77. PMID 9747029. doi:10.1007/s100380050063 .
Sossey-Alaoui K, Srivastava AK. DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX). Genomics. May 1999, 56 (1): 121–6. PMID 10036192. doi:10.1006/geno.1998.5718.
- Nagase T, Ishikawa K, Nakajima D, et al. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.. DNA Res. 1997, 4 (2): 141–50. PMID 9205841. doi:10.1093/dnares/4.2.141 .
- Matsumoto N, Pilz DT, Ledbetter DH. Genomic structure, chromosomal mapping, and expression pattern of human DCAMKL1 (KIAA0369), a homologue of DCX (XLIS).. Genomics. 1999, 56 (2): 179–83. PMID 10051403. doi:10.1006/geno.1998.5673.
- Lin PT, Gleeson JG, Corbo JC, et al. DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization.. J. Neurosci. 2001, 20 (24): 9152–61. PMID 11124993. doi:10.1523/JNEUROSCI.20-24-09152.2000 .
- Burgess HA, Reiner O. Alternative splice variants of doublecortin-like kinase are differentially expressed and have different kinase activities.. J. Biol. Chem. 2002, 277 (20): 17696–705. PMID 11884394. doi:10.1074/jbc.M111981200 .
- Kim MH, Derewenda U, Devedjiev Y, et al. Purification and crystallization of the N-terminal domain from the human doublecortin-like kinase.. Acta Crystallogr. D. 2003, 59 (Pt 3): 502–5. PMID 12595708. doi:10.1107/S0907444903000027.
- Kim MH, Cierpicki T, Derewenda U, et al. The DCX-domain tandems of doublecortin and doublecortin-like kinase.. Nat. Struct. Biol. 2003, 10 (5): 324–33. PMID 12692530. doi:10.1038/nsb918.
- Seet LF, Liu N, Hanson BJ, Hong W. Endofin recruits TOM1 to endosomes.. J. Biol. Chem. 2004, 279 (6): 4670–9. PMID 14613930. doi:10.1074/jbc.M311228200 .
- Ballif BA, Villén J, Beausoleil SA, et al. Phosphoproteomic analysis of the developing mouse brain.. Mol. Cell. Proteomics. 2005, 3 (11): 1093–101. PMID 15345747. doi:10.1074/mcp.M400085-MCP200 .
- PDB中UniProt可用的所有結構資訊之概述:O15075 (Serine/threonine-protein kinase DCLK1) 在PDBe-KB。