PER3

PER3
识别号
别名	PER3；, GIG13, FASPS3, period circadian clock 3, period circadian regulator 3
外部ID	OMIM：603427 MGI：1277134 HomoloGene：7886 GeneCards：PER3
相关疾病
	advanced sleep phase syndrome 3
基因位置（人类）
染色体	1号染色体
终止	7,845,177 bp
基因位置（小鼠）
染色体	小鼠4号染色体
终止	151,044,665 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• 泛素蛋白连接酶结合; • 激酶结合; • 血浆蛋白结合; • transcription cis-regulatory region binding; • transcription corepressor binding; • 转录因子结合;
细胞组分	• 细胞质; • 细胞核;
生物学过程	• 昼夜节律; • circadian regulation of gene expression; • rhythmic process; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • regulation of circadian sleep/wake cycle, sleep; • protein stabilization; • negative regulation of transcription by RNA polymerase II; • response to light stimulus; • entrainment of circadian clock by photoperiod;
	Sources:Amigo / QuickGO
直系同源
	8863
	18628
	ENSG00000049246
	ENSMUSG00000028957
	P56645
	O70361
NM_001289861; NM_001289862; NM_001289863; NM_001289864; NM_016831;
	NM_001377275; NM_001377276
	NM_011067; NM_001289877; NM_001289878
NP_001276790; NP_001276791; NP_001276792; NP_001276793; NP_058515;
	NP_001364204; NP_001364205
	NP_001276806; NP_001276807; NP_035197
	维基数据
查看/编辑人类	查看/编辑小鼠

PER3是由人类基因per3 编码的蛋白质，全称“昼夜节律蛋白同源物3”（英语：period circadian protein homolog 3），是PER1和PER2的旁系同源体^[6]，和睡眠相位后移症候群有关^[7]。

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参考文献

[1]
與PER3相關的疾病；在維基數據上查看/編輯參考.
[2]
GRCh38: Ensembl release 89: ENSG00000049246 - Ensembl, May 2017
[3]
GRCm38: Ensembl release 89: ENSMUSG00000028957 - Ensembl, May 2017
[4]
Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
[5]
Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
[6]
Shearman LP, Zylka MJ, Weaver DR, Kolakowski LF, Reppert SM. Two period homologs: circadian expression and photic regulation in the suprachiasmatic nuclei. Neuron. December 1997, 19 (6): 1261–9. PMID 9427249. S2CID 10059149. doi:10.1016/S0896-6273(00)80417-1 .
[7]
Archer SN, Robilliard DL, Skene DJ, Smits M, Williams A, Arendt J, von Schantz M. A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep. June 2003, 26 (4): 413–5. PMID 12841365. doi:10.1093/sleep/26.4.413 .

PER3引用了美国国家医学图书馆提供的资料，这些资料属于公共领域。