CD24

CD24（分化簇24，英语：cluster of differentiation 24，也称为热稳定抗原CD24，英语：heat stable antigen CD24）是一个人类基因 CD24 编码的蛋白质，是一种细胞粘附分子^[5]。

CD24
识别号
别名	CD24；, CD24A, CD24 molecule
外部ID	OMIM：600074 MGI：88323 GeneCards：CD24
基因位置（人类） 染色体 6号染色体[1] 基因座 6q21 起始 106,969,831 bp[1] 终止 106,975,627 bp[1]
基因位置（小鼠） 染色体 小鼠10号染色体[2] 基因座 10 B2|10 23.01 cM 起始 43,454,280 bp[2] 终止 43,460,261 bp[2]
基因本体 分子功能 • protein tyrosine kinase activator activity • signal transducer activity • 血浆蛋白结合 • protein kinase binding 细胞组分 • 膜 • 细胞膜 • cell surface • anchored component of external side of plasma membrane • 脂筏模型 • anchored component of membrane • 胞内 生物学过程 • response to hypoxia • regulation of MAPK cascade • positive regulation of MAP kinase activity • regulation of cytokine-mediated signaling pathway • positive regulation of cytosolic calcium ion concentration • chemokine receptor transport out of membrane raft • T cell costimulation • regulation of phosphorylation • Wnt信号通路 • negative regulation of transforming growth factor beta3 production • cell activation • immune response-regulating cell surface receptor signaling pathway • response to estrogen • 呼吸爆发 • intrinsic apoptotic signaling pathway • glomerular parietal epithelial cell differentiation • 细胞粘附 • glomerular visceral epithelial cell differentiation • cholesterol homeostasis • regulation of epithelial cell differentiation • response to molecule of bacterial origin • 细胞迁移 • B cell receptor transport into membrane raft • positive regulation of nephron tubule epithelial cell differentiation • positive regulation of activated T cell proliferation • positive regulation of protein tyrosine kinase activity • cell-cell adhesion Sources:Amigo / QuickGO
直系同源
物种	人类	小鼠
Entrez	100133941	12484
Ensembl	ENSG00000272398	ENSMUSG00000047139
UniProt	P25063	P24807
mRNA​序列	NM_001291737 ​NM_001291738 ​NM_001291739 ​NM_013230 ​NM_001359084	NM_009846
蛋白序列	NP_001278666 ​NP_001278667 ​NP_001278668 ​NP_037362 ​NP_001346013	NP_033976
基因位置​（UCSC）	Chr 6: 106.97 – 106.98 Mb	Chr 10: 43.45 – 43.46 Mb
PubMed​查找	[3]	[4]
维基数据
查看/编辑人类 查看/编辑小鼠

参考文献

1. GRCh38: Ensembl release 89: ENSG00000272398 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047139 - Ensembl, May 2017
3. Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hough MR, Rosten PM, Sexton TL, Kay R, Humphries RK. Mapping of CD24 and homologous sequences to multiple chromosomal loci. Genomics. July 1994, 22 (1): 154–61. PMID 7959762. doi:10.1006/geno.1994.1356.

外部链接

• 医学主题词表（MeSH）：CD24+Antigen
• Mouse CD Antigen Chart
• Human CD Antigen Chart （页面存档备份，存于互联网档案馆）
• www.copewithcytokines.de: description of CD24 expression （页面存档备份，存于互联网档案馆）
• Template:UCSC genome browser
• Template:UCSC gene details