氯己定是一种非常有效的抗菌剂,其在新生儿脐带护理方面的使用在世界各地不断增长。在一份2015年考科蓝合作组织发表的审查报告,有高品质的证据显示在社区环境中,使用氯己定进行皮肤或脐带护理可将新生儿脐炎(英语:Omphalitis of newborn)的发生率降低50%,将新生儿死亡率降低12%。[36]
氯己定不符合欧洲手部消毒剂规范。在欧洲标准EN 1499的测试条件下,含4%的葡萄糖酸氯己定溶液与肥皂的功效并无显著差异。美国里士满退伍军人管理医疗中心(英语:Richmond Veterans Medical Cente)于2007年至2009年间进行一项整群随机试验,结论是每天对加护病房患者使用浸有氯己定葡糖酸盐的毛巾洗澡,可降低其发生医疗照顾相关感染的风险。[38]
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