Sistéin

Sistéina atawa sistéin (lambang Cys atawa C;^[3] /ˈsɪstɪiːn/)^[4] nyaéta asam amino protéinogenik semiésénsial^[5] anu rumusna HOOC-CH-(NH₂)-CH₂-SH. Ranté gigir tiol dina sistéin osok kapaké dina réaksi énzimatik salaku nukléopil.

Artikel ieu lain ngeunaan sitosin, sistin, sitisin, atawa sitidin.

“Cys” dialihkeun ka dieu. Pikeun kagunaan séjén, tempo Cys (disambiguasi).

l-Sistéin

Rumus rangka L-sistéin
Modél bal jeung stik Modél ngeusi rohang
Wasta
Wasta IUPAC Cysteine
Wasta lian Asam 2-amino-3-sulphidrilpropanoat
Pananda
Nomer CAS	52-90-4 Y 52-89-1 (hidroklorida) Y
Modél 3D (JSmol)	Gambar interaktif Zwitterion: Gambar interaktif
Abbreviations	Cys, C
ChEBI	CHEBI:15356 Y
ChEMBL	ChEMBL54943 Y
ChemSpider	574 (Rasemat) Y 5653 (L-form) Y
ECHA InfoCard	100.000.145
Nomer EC	200-158-2
Nomer E	E920 (palapis, ...)
IUPHAR/BPS	4782
KEGG	D00026 Y
PubChem CID	5862
UNII	K848JZ4886 Y A9U1687S1S (hydrochloride) Y
CompTox Dashboard (EPA)	DTXSID8022876
InChI InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6) Y Key: XUJNEKJLAYXESH-UHFFFAOYSA-N Y InChI=1/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1 Key: XUJNEKJLAYXESH-REOHCLBHBU InChI=1/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6) Key: XUJNEKJLAYXESH-UHFFFAOYAC
SMILES C([C@@H](C(=O)O)N)S Zwitterion: C([C@@H](C(=O)[O-])[NH3+])S
Sipat[1]
Rumus kimia	C3H7NO2S
Massa molar	12115 g·mol−1
Panampilan	tipung atawa kristal bodas
Titik lebur	240 °C (464 °F; 513 K) decomposes
Kelarutan dina cai	soluble
Solubilitas	1.5g/100g étanol 19 degC [2]
Rotasi kiral ([α]D)	+9.4° (H2O, c = 1.3)
Iwal disebutkeun séjén, data nu dipidangkeun keur matéri dina kaayaan baku (dina 25 °C, 100 kPa).
N verifikasi (naon ieu YN ?)
Rujukan kotak info

Nalika aya salaku résidu katalitik deprotonasi, kadang simbol Cyz dipaké.^[6][7] Wangun deprotonasi umumna bisa maké simbol Cym ogé.^[8] Ieu tiol babari kaoksidasi jadi turunan disulpida sistin, anu boga pancén struktural penting dina protéin. Dina ieu kasus, simbol Cyx kadang dipaké.^[8] Nalika dipaké aditip dahareun, nomer E-na E920.

Sistéin dikode ku kodon UGU jeung UGC.

Sistéin jeung métionin anu ngandung walirang leuwih babari kaoksidasi batan asam amino lianna.^[9][10]

Baca ogé

• Métabolisme sistéin
• Sistinuria
• Réaksi Saville
• Réaksi Sullivan

Rujukan

1. Citakan:RubberBible62nd.
2. Belitz, H.-D; Grosch, Werner; Schieberle, Peter (2009-02-27). Food Chemistry. ISBN 9783540699330.
3. Citakan:IUPAC-IUB amino acids 1983
4. "cysteine - Definition of cysteine in English by Oxford Dictionaries". Oxford Dictionaries - English. Diakses tanggal 15 April 2018. Archived 25 Séptémber 2016 di Wayback Machine
5. "The primary structure of proteins is the amino acid sequence". The Microbial World. University of Wisconsin-Madison Bacteriology Department. Diarsipkan dari versi asli tanggal 25 May 2013. Diakses tanggal 16 September 2012. Unknown parameter |url-status= ignored (bantuan) Archived 25 Méi 2013 di Wayback Machine
6. "python - How can I programmatically add Hydrogen to a PDB structure using BioPython?". Bioinformatics Stack Exchange. Diakses tanggal 2022-05-12.
7. "type of docking | RosettaCommons". www.rosettacommons.org. Diakses tanggal 2022-05-12.
8. "Amber Workshop - Tutorial A1 - Section 1: Do some editing of the PDB file". ambermd.org. Diakses tanggal 2022-06-02. Archived 2022-05-22 di Wayback Machine
9. Bin, P; Huang, R; Zhou, X (2017). "Oxidation Resistance of the Sulfur Amino Acids: Methionine and Cysteine.". BioMed research international 2017: 9584932. doi:10.1155/2017/9584932. PMC 5763110. PMID 29445748. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5763110.
10. "Functions and evolution of selenoprotein methionine sulfoxide reductases". Biochimica et Biophysica Acta (BBA) - General Subjects 1790 (11): 1471–1477. 2009. doi:10.1016/j.bbagen.2009.04.014. PMC 3062201. PMID 19406207. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3062201.

Bacaan salajengna

• "Strong hydrophobic nature of cysteine residues in proteins". FEBS Lett. 458 (1): 69–71. September 1999. doi:10.1016/S0014-5793(99)01122-9. PMID 10518936.

Tutumbu kaluar

• Cysteine MS Spectrum
• International Kidney Stone Institute Archived 2019-05-13 di Wayback Machine
• http://www.chemie.fu-berlin.de/chemistry/bio/aminoacid/cystein en.html Archived 2016-11-10 di Wayback Machine
• 952-10-3056-9 Interaction of alcohol and smoking in the pathogenesis of upper digestive tract cancers - possible chemoprevention with cysteine
• Cystine Kidney Stones
• Kosher View of L-Cysteine

Citakan:E number infobox 920-929 Citakan:Intermédiat métabolisme amino amino