Aneuploidy
presence of an abnormal number of specific chromosomes in a cell From Wikipedia, the free encyclopedia
Aneuploidy is a condition where the nucleus of a cell has one or a few chromosomes more or less than the usual number in the species.[1] It is a common cause of genetic disorders. Aneuploidy occurs during cell division when the chromosomes do not separate properly between the two cells.[2]
Aneuploidy often causes birth defects and miscarriages.[3] Birth defects make up about 3% of births in the United States.[4] Among those who survive birth, Down syndrome is the most common form of aneuploidy.[5] Many with Down syndrome do survive to adulthood.[5] Some cancer cells also have abnormal numbers of chromosomes.[6] The aneuploid theory of cancer suggests that aneuploidy is a cause of cancer rather than a result of it.[7]
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