Apixabanum est factoris Xa inhibitor atque substantia anticoagulans in thrombosibus venosis tractandis et fibrillatione atriali[1]. Usus additus embolismorum pulmonum sive providentiae apoplexiae cerebri est.
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Cognitores | |
---|---|
ChemSpider | 8358471 |
PubChem | 10182969 |
DrugBank | DB07828 |
Natura chemica | |
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Formula chemica | C 25H 25N 5O 4 |
Massa molaris | 459.497 g/mol |
Natura pharmacologica | |
Codex ATC | B01AF02 (WHO) |
Tempus semivitae biologicum | 9-14 h |
Metabolismus | iecore (hepaticus) CYP3A4, CYP3A5, CYP1A2 et al. |
Excretio | faecibus: 75%, renibus: 25% |
Ad usum therapeuticum | |
Applicatio | per os |
MedlinePlus | a613032 (Anglice) |
Natura Apixabani
Natura chemica
Apixabanum est pyrazolopyridinum cum gregibus chemicis lactami et piperidini.
Apixabanum est substratum cytochromatis CYP3A4[2]. Massa molaris est 459.497 g/mol.
Nexus interni
Notae
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