カベオリン1ウィキペディア フリーな encyclopedia カベオリン1(英: caveolin 1)は、ヒトではCAV1遺伝子によってコードされるタンパク質である[5]。 概要 CAV1, 識別子 ...CAV1識別子記号CAV1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, Caveolin 1外部IDOMIM: 601047 MGI: 102709 HomoloGene: 1330 GeneCards: CAV1 遺伝子の位置 (ヒト)染色体7番染色体 (ヒト)[1]バンドデータ無し開始点116,524,994 bp[1]終点116,561,179 bp[1]遺伝子の位置 (マウス)染色体6番染色体 (マウス)[2]バンドデータ無し開始点17,306,334 bp[2]終点17,341,451 bp[2]RNA発現パターンさらなる参照発現データ遺伝子オントロジー分子機能• protein-macromolecule adaptor activity• transmembrane transporter binding• 構造分子活性• 受容体結合• nitric-oxide synthase binding• patched binding• 酵素結合• peptidase activator activity• 血漿タンパク結合• molecular adaptor activity• プロテインキナーゼ結合• ATPase binding• cholesterol binding• inward rectifier potassium channel inhibitor activity• identical protein binding• protein heterodimerization activity• protein-containing complex binding細胞の構成要素• endocytic vesicle membrane• エンドソーム• 膜• 焦点接着• VCP-NPL4-UFD1 AAA ATPase complex• perinuclear region of cytoplasm• カベオラ• 繊毛• apical plasma membrane• 小胞体• 脂質ラフト• integral component of membrane• ゴルジ体• early endosome membrane• 細胞膜• 細胞内• 細胞皮質• endoplasmic reticulum membrane• ゴルジ膜• integral component of plasma membrane• acrosomal membrane• basolateral plasma membrane• cytoplasmic vesicle• 脂肪滴• 細胞質• 高分子複合体• 筋鞘生物学的プロセス• caveolin-mediated endocytosis• positive regulation of calcium ion transport into cytosol• 血管収縮• response to progesterone• negative regulation of protein binding• regulation of peptidase activity• protein localization to plasma membrane raft• 乳房発達• 脈管形成• negative regulation of pinocytosis• response to ischemia• 血管新生• apoptotic signaling pathway• positive regulation of extrinsic apoptotic signaling pathway• cholesterol homeostasis• triglyceride metabolic process• negative regulation of canonical Wnt signaling pathway• calcium ion transport• negative regulation of cell population proliferation• cellular response to transforming growth factor beta stimulus• positive regulation of toll-like receptor 3 signaling pathway• regulation of cytosolic calcium ion concentration• regulation of smooth muscle contraction• vesicle organization• negative regulation of peptidyl-tyrosine autophosphorylation• regulation of cardiac muscle cell action potential involved in regulation of contraction• negative regulation of transforming growth factor beta receptor signaling pathway• protein localization to basolateral plasma membrane• receptor internalization involved in canonical Wnt signaling pathway• regulation of membrane repolarization during action potential• positive regulation of peptidyl-serine phosphorylation• negative regulation of protein tyrosine kinase activity• regulation of entry of bacterium into host cell• negative regulation of MAP kinase activity• positive regulation of vasoconstriction• negative regulation of potassium ion transmembrane transport• 授乳• receptor-mediated endocytosis of virus by host cell• regulation of blood coagulation• regulation of ventricular cardiac muscle cell action potential• protein homooligomerization• viral process• positive regulation of intrinsic apoptotic signaling pathway• negative regulation of receptor signaling pathway via JAK-STAT• mammary gland involution• calcium ion homeostasis• negative regulation of necroptotic process• regulation of the force of heart contraction• lipid storage• nitric oxide homeostasis• 膜脱分極• negative regulation of cytokine-mediated signaling pathway• cellular calcium ion homeostasis• negative regulation of transcription by RNA polymerase II• response to estrogen• response to calcium ion• regulation of fatty acid metabolic process• cellular response to exogenous dsRNA• negative regulation of MAPK cascade• regulation of ruffle assembly• positive regulation of protein binding• positive regulation of protein ubiquitination• negative regulation of anoikis• leukocyte migration• タンパク質局在化• positive regulation of cell adhesion molecule production• 低酸素症への反応• negative regulation of nitric-oxide synthase activity• 細菌への反応• caveola assembly• cellular response to hyperoxia• cholesterol transport• cellular response to starvation• T cell costimulation• regulation of nitric-oxide synthase activity• receptor internalization• positive regulation of peptidase activity• positive regulation of ER-associated ubiquitin-dependent protein catabolic process• negative regulation of endothelial cell proliferation• negative regulation of BMP signaling pathway• negative regulation of protein ubiquitination• cellular response to peptide hormone stimulus• positive regulation of gene expression• negative regulation of nitric oxide biosynthetic process• angiotensin-activated signaling pathway involved in heart process• protein complex oligomerization• negative regulation of peptidyl-serine phosphorylation• posttranscriptional regulation of gene expression• positive regulation of gap junction assembly• maintenance of protein location in cell• negative regulation of signal transduction• regulation of the force of heart contraction by chemical signal• regulation of cell communication by electrical coupling involved in cardiac conduction• regulation of heart rate by cardiac conduction• negative regulation of epithelial cell differentiation• skeletal muscle tissue development• beta-catenin destruction complex disassembly• positive regulation of catalytic activity• positive regulation of canonical Wnt signaling pathway• negative regulation of tyrosine phosphorylation of STAT protein• negative regulation of inward rectifier potassium channel activity• 細胞分化• positive regulation of cell migration• positive regulation of cold-induced thermogenesis• positive regulation of NF-kappaB transcription factor activity出典:Amigo / QuickGOオルソログ種ヒトマウスEntrez85712389EnsemblENSG00000105974ENSMUSG00000007655UniProtQ03135,C9JKI3P49817RefSeq(mRNA)NM_001753NM_001172895NM_001172896NM_001172897NM_001243064NM_007616RefSeq(タンパク質)NP_001166366NP_001166367NP_001166368NP_001744NP_001229993NP_031642場所(UCSC)Chr 7: 116.52 – 116.56 MbChr 7: 17.31 – 17.34 MbPubMed検索[3][4]ウィキデータ閲覧/編集 ヒト閲覧/編集 マウス閉じる
カベオリン1(英: caveolin 1)は、ヒトではCAV1遺伝子によってコードされるタンパク質である[5]。 概要 CAV1, 識別子 ...CAV1識別子記号CAV1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, Caveolin 1外部IDOMIM: 601047 MGI: 102709 HomoloGene: 1330 GeneCards: CAV1 遺伝子の位置 (ヒト)染色体7番染色体 (ヒト)[1]バンドデータ無し開始点116,524,994 bp[1]終点116,561,179 bp[1]遺伝子の位置 (マウス)染色体6番染色体 (マウス)[2]バンドデータ無し開始点17,306,334 bp[2]終点17,341,451 bp[2]RNA発現パターンさらなる参照発現データ遺伝子オントロジー分子機能• protein-macromolecule adaptor activity• transmembrane transporter binding• 構造分子活性• 受容体結合• nitric-oxide synthase binding• patched binding• 酵素結合• peptidase activator activity• 血漿タンパク結合• molecular adaptor activity• プロテインキナーゼ結合• ATPase binding• cholesterol binding• inward rectifier potassium channel inhibitor activity• identical protein binding• protein heterodimerization activity• protein-containing complex binding細胞の構成要素• endocytic vesicle membrane• エンドソーム• 膜• 焦点接着• VCP-NPL4-UFD1 AAA ATPase complex• perinuclear region of cytoplasm• カベオラ• 繊毛• apical plasma membrane• 小胞体• 脂質ラフト• integral component of membrane• ゴルジ体• early endosome membrane• 細胞膜• 細胞内• 細胞皮質• endoplasmic reticulum membrane• ゴルジ膜• integral component of plasma membrane• acrosomal membrane• basolateral plasma membrane• cytoplasmic vesicle• 脂肪滴• 細胞質• 高分子複合体• 筋鞘生物学的プロセス• caveolin-mediated endocytosis• positive regulation of calcium ion transport into cytosol• 血管収縮• response to progesterone• negative regulation of protein binding• regulation of peptidase activity• protein localization to plasma membrane raft• 乳房発達• 脈管形成• negative regulation of pinocytosis• response to ischemia• 血管新生• apoptotic signaling pathway• positive regulation of extrinsic apoptotic signaling pathway• cholesterol homeostasis• triglyceride metabolic process• negative regulation of canonical Wnt signaling pathway• calcium ion transport• negative regulation of cell population proliferation• cellular response to transforming growth factor beta stimulus• positive regulation of toll-like receptor 3 signaling pathway• regulation of cytosolic calcium ion concentration• regulation of smooth muscle contraction• vesicle organization• negative regulation of peptidyl-tyrosine autophosphorylation• regulation of cardiac muscle cell action potential involved in regulation of contraction• negative regulation of transforming growth factor beta receptor signaling pathway• protein localization to basolateral plasma membrane• receptor internalization involved in canonical Wnt signaling pathway• regulation of membrane repolarization during action potential• positive regulation of peptidyl-serine phosphorylation• negative regulation of protein tyrosine kinase activity• regulation of entry of bacterium into host cell• negative regulation of MAP kinase activity• positive regulation of vasoconstriction• negative regulation of potassium ion transmembrane transport• 授乳• receptor-mediated endocytosis of virus by host cell• regulation of blood coagulation• regulation of ventricular cardiac muscle cell action potential• protein homooligomerization• viral process• positive regulation of intrinsic apoptotic signaling pathway• negative regulation of receptor signaling pathway via JAK-STAT• mammary gland involution• calcium ion homeostasis• negative regulation of necroptotic process• regulation of the force of heart contraction• lipid storage• nitric oxide homeostasis• 膜脱分極• negative regulation of cytokine-mediated signaling pathway• cellular calcium ion homeostasis• negative regulation of transcription by RNA polymerase II• response to estrogen• response to calcium ion• regulation of fatty acid metabolic process• cellular response to exogenous dsRNA• negative regulation of MAPK cascade• regulation of ruffle assembly• positive regulation of protein binding• positive regulation of protein ubiquitination• negative regulation of anoikis• leukocyte migration• タンパク質局在化• positive regulation of cell adhesion molecule production• 低酸素症への反応• negative regulation of nitric-oxide synthase activity• 細菌への反応• caveola assembly• cellular response to hyperoxia• cholesterol transport• cellular response to starvation• T cell costimulation• regulation of nitric-oxide synthase activity• receptor internalization• positive regulation of peptidase activity• positive regulation of ER-associated ubiquitin-dependent protein catabolic process• negative regulation of endothelial cell proliferation• negative regulation of BMP signaling pathway• negative regulation of protein ubiquitination• cellular response to peptide hormone stimulus• positive regulation of gene expression• negative regulation of nitric oxide biosynthetic process• angiotensin-activated signaling pathway involved in heart process• protein complex oligomerization• negative regulation of peptidyl-serine phosphorylation• posttranscriptional regulation of gene expression• positive regulation of gap junction assembly• maintenance of protein location in cell• negative regulation of signal transduction• regulation of the force of heart contraction by chemical signal• regulation of cell communication by electrical coupling involved in cardiac conduction• regulation of heart rate by cardiac conduction• negative regulation of epithelial cell differentiation• skeletal muscle tissue development• beta-catenin destruction complex disassembly• positive regulation of catalytic activity• positive regulation of canonical Wnt signaling pathway• negative regulation of tyrosine phosphorylation of STAT protein• negative regulation of inward rectifier potassium channel activity• 細胞分化• positive regulation of cell migration• positive regulation of cold-induced thermogenesis• positive regulation of NF-kappaB transcription factor activity出典:Amigo / QuickGOオルソログ種ヒトマウスEntrez85712389EnsemblENSG00000105974ENSMUSG00000007655UniProtQ03135,C9JKI3P49817RefSeq(mRNA)NM_001753NM_001172895NM_001172896NM_001172897NM_001243064NM_007616RefSeq(タンパク質)NP_001166366NP_001166367NP_001166368NP_001744NP_001229993NP_031642場所(UCSC)Chr 7: 116.52 – 116.56 MbChr 7: 17.31 – 17.34 MbPubMed検索[3][4]ウィキデータ閲覧/編集 ヒト閲覧/編集 マウス閉じる