PEST sequence
Peptide sequence in short-lived proteins From Wikipedia, the free encyclopedia
A PEST sequence is a peptide sequence that is rich in proline (P), glutamic acid (E), serine (S) and threonine (T). It is associated with proteins that have a short intracellular half-life, so might act as a signal peptide for protein degradation.[1] This may be mediated via the proteasome[2][3] or calpain.[4]
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