MOBKL3

Mps one binder kinase activator-like 3 is an enzyme that in humans is encoded by the MOBKL3 gene.^[5][6][7][8]

MOB4
Identifiers
Aliases	MOB4, 2C4D, MOB1, MOB3, MOBKL3, PHOCN, PREI3, CGI-95, MOB family member 4, phocein
External IDs	OMIM: 609361; MGI: 104899; HomoloGene: 9116; GeneCards: MOB4; OMA:MOB4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q33.1 Start 197,515,571 bp[1] End 197,553,699 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C1.2 Start 55,170,390 bp[2] End 55,194,058 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Skeletal muscle tissue of biceps brachii right ventricle thoracic diaphragm deltoid muscle Skeletal muscle tissue of rectus abdominis vastus lateralis muscle myocardium triceps brachii muscle tibialis anterior muscle myocardium of left ventricle Top expressed in adrenal gland interventricular septum medial ganglionic eminence parotid gland left lung lobe migratory enteric neural crest cell vas deferens vastus lateralis muscle atrioventricular valve abdominal wall More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding kinase binding Cellular component cytoplasm perinuclear region of cytoplasm Golgi cisterna membrane Golgi apparatus membrane cytosol soma dendritic spine Biological process transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25843 19070 Ensembl ENSG00000115540 ENSMUSG00000025979 UniProt Q9Y3A3 Q6PEB6 RefSeq (mRNA) NM_199482 NM_001100819 NM_001204094 NM_015387 NM_025283 NM_001310585 RefSeq (protein) NP_001094289 NP_001191023 NP_056202 NP_955776 NP_001297514 NP_079559 Location (UCSC) Chr 2: 197.52 – 197.55 Mb Chr 1: 55.17 – 55.19 Mb PubMed search [3] [4]
Wikidata
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Function

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed.^[8]

Interactions

MOBKL3 has been shown to interact with:

• CTTNBP2NL,^[9]
• CTTNBP2,^[9]
• FAM40A,^[9]
• PDCD10,^[9]
• PPP2CA,^[9]
• RP6-213H19.1,^[9]
• STK24,^[9][10]
• STK25,^[9]
• STRN3,^[9]
• STRN,^[9] and
• TRAF3IP3.^[9]