Irene (Ancient Greek: Ειρήνη, romanized: Eirḗnē), sometimes written Irini, is derived from εἰρήνη, the Greek word for "peace".[1] Eirene was the Greek goddess of peace.[2] Irene was also the name of an 8th-century Byzantine empress (Irene of Athens), as well as the name of several saints (see Saint Irene).
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- Arina (Russian)
- Arisha (Russian)
- Eireen (English, Irish)
- Eirena (English)
- Eirene (English, Greek)
- Eirini (Greek)
- Eraina (English)
- Erayna (English)
- Erea (Galicia)
- Erene (English)
- Ereni (Greek)
- Eriny (Greek, similar to the pronunciation of)
- Ira (Indonesian, Russian, Ukrainian)
- Ireen (English)
- Iren (English) (Indonesian)
- Irén (Hungarian)
- Irena (Albanian, Croatian, Czech, Dutch, English, Indonesian, Latvian, Lithuanian, Macedonian, Polish, Serbian, Slovak, Slovenian)
- Irene (Dutch, English, Italian, Latvian, Spanish, Portuguese)
- Irène (French)
- Irenea (Spanish)
- Irenka (Czech, Polish, Slovak)
- Iria (Galician, Portuguese)
- Iriana (English)
- Iriana, Irene (Indonesian)
- Iriena (English)
- Irin (English)
- Irini (Albanian)
- Irina (Bulgarian, Finnish, Romanian, Russian)
- Irine (English)
- Irina (Russian, Romanian)
- Irinka (Russian)
- Irishka (Russian, Ukrainian)
- Irinushka (Russian)
- Irisha (Russian)
- Irja (Finnish)
- Irka (Czech)
- Iryna (English, Ukrainian)
- Irynka (Ukrainian)
- Irynochka (Ukrainian)
- Reeni (English)
- Reeny (English)
- Rena (English, Indonesian, Greek)
- Rene (English)
- Reney (English)
- Reni (English, Indonesian)
- Renie (English)
- Rina (Indonesian, Russian)
- Yarina (Russian)
- Yaryna (Ukrainian)
- Yeran (Armenian)
- Yeranouhi (Armenian)
- Irene, baptismal name of Tzitzak (died 750), wife of Byzantine Emperor Constantine V
- Irene of Athens (c. 752 – 803), wife of Byzantine Emperor Leo IV and empress regnant, 797–802
- Irene of Hungary (1088–1134), empress consort of John II Komnenos of the Byzantine Empire
- Irene Angelina (fl. late 1100s)
- Irene Dushmani (15th century), Albanian Princess of Zadrima and Pult
- Irene Shpata (14th century) Albanian Princess of Arta and Despotess consort of Epirus
- Princess Irene of Greece and Denmark (1904–1974), later Duchess of Aosta, Queen of Croatia
- Princess Irene of Greece and Denmark (born 1942)
- Princess Irene of the Netherlands (born 1939)
- Princess Irene of Hesse and by Rhine (1866–1953)
- Saint Irene (disambiguation), various saints
- Eirene (artist), ancient Greek artist
- Irene (singer) (born 1991), South Korean singer
- Irene Abel (born 1953), East German gymnast
- Irene Abendroth (1872–1932), Austrian operatic soprano
- Irene Abrigo (born 1988), Italian violinist
- Irene Adams (born 1947), Scottish politician
- Irene Aebi (born 1939), Swiss singer, violinist and cellist
- Irene Aguilar (born 1960), American politician
- Irene Agyepong (born 1960), Ghanaian public health physician
- Irene Ajambo (born 1987), Ugandan weightlifter
- Irene Zoe Alameda, Spanish writer, filmmaker and composer
- Irene Alexander, Australian spiritual director, writer and lecturer
- Irene Osgood Andrews (1879–1963), American writer
- Irene Ang (born 1969), Singaporean actress, comedian, host and entrepreneur
- Irene Angelico, Canadian film director, producer and writer
- Irene Kataq Angutitok (1914–1971), Inuit sculptor
- Irene Arcos (born 1981), Spanish actress
- Irene Aronson, German-American painter
- Irene Astor, Baroness Astor of Hever (1919–2001), English philanthropist
- Irene Avaalaaqiaq Tiktaalaaq (born 1941), Canadian artist
- Irene Awret (1921–2014), German artist and writer
- Irene Azuela (born 1979), Mexican actress and producer
- Irene Bache (1901–1999), British artist
- Irene Baird, English-Canadian novelist
- Irene Baker (botanist) (1918–1989), British-born American botanist
- Irene Baker (1901–1994), American politician
- Irene Baldessari (born 1993), Italian middle-distance runner
- Irene Barberis (born 1953), Australian artist
- Irene Barclay (1894–1989), British surveyor
- Irene Barros (1930–2021), Indian politician
- Irene Bayer-Hecht (1898–1991), American photographer
- Irene Beardsley (born 1935), American mountaineer
- Irene Beasley (1904–1980), American singer
- Irene Blanco Becerra (born 1946), Mexican politician
- Irene Becker, German nurse and serial killer
- Irene Bedard (born 1967), Native American actress
- Irene Beland, American nursing educator and patient-centered care researcher
- Irene Bell Bonong (born 1995), Cameroonian sprinter
- Irene Below, German art historian
- Irene Benneweis (1891–1970), Danish acrobat and circus director
- Irene Bentley (1870–1940), American actress
- Irene Berger (born 1954), American judge
- Irene Bernasconi (1896–1989), Argentine marine biologist
- Irene Bertschek, German economist
- Irene Beyeler (born 1985), Swiss sport shooter
- Irene Beyerlein, American materials scientist
- Irene Bianucci (1903–1988), Italian-American painter
- Irene Bitto (born 1993), Italian cyclist
- Irene Craigmile Bolam (1904–1982), American banker and former aviator
- Irene Borrego (born 2001), Mexican weightlifter
- Irene Bosch, Venezuelan biologist and researcher
- Irene Mott Bose, American social worker
- Irene Bridger (21st century), Canadian singer
- Irene Brietzke (1944–2021), Brazilian actress and theatre director
- Irene Brin (1911–1969), Italian journalist and writer
- Irene Britton Smith (1907–1999), American classical composer
- Irene Broe (1923–1992), Irish sculptor
- Irene Brown (1919–2017), British code breaker
- Irene Bennett Brown, American author
- Irene Browne (1891–1965), British actress
- Irene Mary Browne (1881–1977), British artist
- Irene Bucher, Swiss orienteering competitor
- Irene Bürgi, Swiss curler
- Irene Burillo Escorihuela (born 1997), Spanish tennis player
- Irene Burns, American television producer
- Irene Bustamante Adams, American politician
- Irene Byers (1906–1992), English novelist, poet and children’s writer
- Irene Caba Alba (1905–1957), Spanish actress
- Irene Cabrera Lorenzo, Spanish former volleyball player
- Irene Cadurisch (born 1991), Swiss biathlete
- Irene Calvert (1909–2000), Northern Irish politician and economist
- Irene Camber (1926–2024), Italian fencer
- Irene Campbell, Scottish Labour politician
- Irene Capek (1924–2006), Australian politician
- Irene Cara (1959–2022), American singer, songwriter, and actress
- Irene Castelli (born 1983), Italian gymnast
- Irene Aragón Castillo (born 1963), Mexican politician
- Irene Castle (1893–1969), half of the ballroom dance team of Vernon and Irene Castle
- Irene Cefaro (1935–2023), Italian stage and film actress
- Irene Champlin (1932–1990), American actress
- Irene Chang, Malaysian politician
- Irene Chanter, British singer
- Irene Charalambidou (born 1964), Cypriot journalist and politician
- Irene Charnley (born 1960), South African businesswoman
- Irene Chen, Australian actress
- Irene Cheng (1904–2007), Hong Kong educationalist
- Irene Chepet Cheptai (born 1992), Kenyan distance runner
- Irene Chou (1924–2011), Chinese artist
- Irene Clarin (born 1955), German television and theatre actress
- Irene Clark Durrell (1852–1914), American educator
- Irene Clark, Navajo weaver
- Irene Coates (1925–2019), English playwright, poet, painter, feminist and environmentalist
- Irene Collins (1925–2015), British historian and writer
- Irene Condachi (1899–1970), Maltese physician
- Irene Cortes (1921–1996), Associate Justice of the Supreme Court of the Philippines
- Irene Cortes (artist), filmmaker and artist
- Irene Costa (born 1972), Portuguese politician and social worker
- Irene Cozad (1888–1970), American pianist, piano teacher and composer
- Irene Crespin (1896–1980), Australian geologist and micro paleontologist
- Irene Cruz, Spanish photographer and video artist
- Irene Cruz-González, Mexican astronomer
- Irene Cuadrado (born 1979), Spanish painter
- Irene Cuesta (born 1983), Spanish archer and archery coach
- Irene Curtoni (born 1985), Italian alpine skier
- Irene Curzon, 2nd Baroness Ravensdale (1896–1966), British hereditary peeress
- Irene Cybulsky, Canadian lawyer and cardiac surgeon
- Irene Dailey (1920–2008), American actress
- Irene Dalby (born 1971), Norwegian swimmer
- Irene Dalis (1925–2014), American opera singer
- Irene Dallas (1883–1971), British suffragette
- Irene Dalton (1901–1934), American actress
- Irene Dare, American figure skater and film star
- Irene Daw (1941–2010), British sports shooter
- Irene Daye (1918–1971), American jazz musician
- Irene Dean-Williams (1903–1946), aviator
- Irene DeBari (born 1947), American television actress
- Irène Debrunner (born 1952), Swiss swimmer
- Irene DeLaby (1922–2012), American baseball player
- Irène Deliège (1933–2024), Belgian cognitive scientist
- Irene Delroy (1900–1985), American stage actress
- Irene Desmet (1928–2020), English pediatric surgeon
- Irene Devin, Wyoming politician
- Irene Diaz, American singer-songwriter
- Irene Dick (born 1949), Curaçaoan politician
- Irene Caroline Diner Koenigsberger (1896–1985), American chemist
- Irene Dingel (born 1956), German historian and Protestant theologian
- Irene Dische (born 1952), American-Austrian writer
- Irene Dixon (1924–2021), Bletchley Park codebreaker
- Irene Dölling (born 1942), German sociologist
- Irene Dorner (born 1954), American businesswoman
- Irene Doukaina (c. 1066–1138), Empress Consort of the Byzantine Empire
- Irene Doutney (c. 1949–2018), Australian politician
- Irène Drésel (born 1984), French electronic music producer
- Irene Drummond, Australian Army nurse
- Irene Dubois, American drag performer
- Irene Dufaux (born 1960), Swiss sport shooter
- Irene Dunne (1898–1990), American actress
- Irene Eastman (1894-1918), American singer
- Irene Eber (1929–2019), Israeli orientalist
- Irene Edgar (born 1957), Scottish lawn bowler
- Irene Eijs (born 1966), Dutch rower
- Irene Eisinger (1903–1994), German-British opera singer and film actress
- Irene Ekelund (born 1997), Swedish sprinter
- Irene Ellenberger (born 1946), German architect
- Irene Emery (1900–1981), American art historian, scholar, curator, textile anthropologist, sculptor, and modern dancer
- Irene Epple (born 1957), German alpine skier
- Irene Escolar (born 1988), Spanish actress
- Irene Esser (born 1991), Venezuelan actress, model and beauty queen
- Irene Evans, musician and educator
- Irene Eyaru, Ugandan netball player
- Irene Fairbairn (1899–1974), Girl Guide Commissioner
- Irene Falcón (1907–1999), Spanish journalist, feminist, pacifist and communist activist
- Irene Fargo (1962–2022), Italian singer and actress
- Irene Fenwick (1887–1936), American actress
- Irene Ferguson, New Zealand painter
- Irene Fernandez (1946–2014), Malaysian human rights activist
- Irene Ferreira (born 1976), Venezuelan model
- Irene Ferreiro (born 2001), Spanish actress, singer and author
- Irene Ferri (born 1972), Italian actress and television presenter
- Irene Fischer (1907–2009), Austrian-American mathematician and geologist
- Irene Fitzner (born 1955), Argentine sprinter
- Irene Fonseca (born 1956), Portuguese-American mathematician
- Irene Foote, several people
- Irene Forbes (1949–2014), Cuban fencer
- Irene Fornaciari (born 1983), Italian singer-songwriter
- Irene Fountas (born 1948), American educational theorist
- Irène Frain (born 1950), French novelist, journalist and historian
- Irene Franchini (born 1981), Italian archer
- Irene Franklin (1885–1941), American actress
- Irene Hanson Frieze, American psychologist and academic
- Irene Frisch (1931–2021), American writer
- Irene Fuhrmann (born 1980), Austrian footballer
- Irene McCoy Gaines (1892–1964), American social worker and civil rights activist
- Irene Galitzine (1916–2006), Russian-Georgian fashion designer
- Irene O. Galloway, American Army soldier
- Irène Galter (1931–2018), Italian actress
- Irene M. Gamba, Argentine-American mathematician
- Irene Gammel (born 1959), Canadian literary historian, biographer and curator
- Irene Gardner (born 1985), American rugby sevens player
- Irene Gargantini, Italian-Canadian computer scientist
- Irene Gattilusio (died 1440), Byzantine Empress consort
- Irene Gauthier (1920–2010), American massage teacher
- Irene Antoinette Geffen, South African lawyer
- Irene Genna (1931–1986), Greek-born Italian film and television actress
- Irene Georgakoudi (born 1971), Greek physicist
- Irini Georgatou (b. 1990), Greek tennis player
- Irene George (born 1983), Solomon Islands tennis player
- Irene Germini (born 1974), Italian rhythmic gymnast
- Irene Ghobrial, American-Egyptian physician and academic
- Irini Giannatou (1917–2000), birth name of Greek actress and singer Rena Dor
- Irene M. Giblin (1888–1974), American pianist and composer
- Irene Gifford, American politician
- Irène Gijbels, mathematical statistician
- Irene Gilbert (1934–2011), German-American actress
- Irene Gilbert (swimmer) (1903–1988), British swimmer
- Irene Gilbert (fashion designer) (c. 1910 – 1985), Irish fashion designer
- Irene Gleeson (1944–2013), Australian aid worker
- Irene Goergens (born 1951), German domestic terrorist
- Irene Gonçalves (born 1984), Angolan footballer
- Irene González, several people
- Iréne Grahn (1945–2013), Swedish visual artist and inventor
- Irene Grandi (born 1969), Italian singer and songwriter
- Irene Greenwood (1898–1992), Australian feminist, pacifist activist, broadcaster and writer
- Irene Gregory, American aerospace engineer
- Irene Greif, American computer scientist
- Irene Griegst (born 1945), Moroccan-born Danish goldsmith
- Irene Griffin (activist), African-American activist
- Irene Griffin, American politician
- Irene Welch Grissom (1873–1965), American poet
- Irene Grootboom, South African housing rights activist
- Irene Güdel (1930–2023), Swiss cellist
- Irene Guerrero (born 1996), Spanish footballer
- Irene Guest (1900–1970), American swimmer
- Irene Gurney (c. 1870–1951), Canadian pianist and clubwoman
- Irene Haines, American politician and businesswoman from Connecticut
- Irene Hall (1888–1961), Australian hospital matron
- Irene Handl (1901–1987), British character actress
- Irene Hannon, American author
- Irene Harand (1900–1975), Austrian human rights activist
- Irene Haschke (born 1921), German SS guard during World War II
- Irene Hayes (1896–1975), American actress
- Irene Hays (born 1953/1954), British civil servant and businesswoman
- Irene Headin, Canadian handball player
- Irene Hedlund (born 1947), Danish illustrator and children’s writer
- Irene Heim (born 1954), American linguist
- Irene Hervey (1909–1998), American film, stage and television actress
- Irene Hess (1910–2009), American statistician
- Irene Hickson (1915–1995), American baseball player
- Irene Higginbotham (1918–1988), American musician
- Irene Hirano (1948–2020), American business executive
- Irene Hirst (1930–2000), British gymnast
- Irene Hoffar Reid (1908–1994), Canadian painter
- Irene Whitfield Holmes (1900–1993), American musicologist and ethnomusicologist
- Irene Hostettler (born 1974), Swiss cyclist
- Irene Howard (1903–1981), British costume designer
- Irene Hughes (1920–2012), American psychic
- Irene Hunt (actress) (1892–1988), American actress
- Irene Hunt (1902–2001), American children's writer
- Irene ʻĪʻī Brown Holloway, Hawaiian philanthropist
- Irene Iacopi, Italian archaeologist
- Irene Ibsen Bille (1901–1985), Norwegian novelist and playwright
- Irene Ighodaro (1916–1995), Sierra Leone Creole physician and social worker
- Irene Ivancan (born 1983), German table tennis player
- Irene Jacob (born 1966), French-born Swiss actress
- Irene Jakab (1919–2011), Hungarian-born psychiatrist
- Irene James, Welsh politician
- Irene Jansen (born 1983), Dutch singer
- Irene Jelagat (born 1988), Kenyan middle-distance runner
- Irene Jerotich Kosgei (born 1974), Kenyan long-distance runner
- Irène Joachim (1913–2001), French soprano and vocal teacher
- Irene Johansen (born 1961), Norwegian politician
- Irène Joliot-Curie (1897–1956), French scientist
- Irene Jones, Canadian politician
- Irene de Jong, Dutch classicist
- Irene Joseph (born 1981), Indonesian sprinter
- Irene Junquera (born 1985), Spanish journalist
- Irene Kampen (1922–1998), American writer
- Irene Kantakouzene (died 1457), wife of Serbian despot
- Irini Karra (born 1986), Greek fashion model
- Eirini Kavarnou (born 1980), Greek swimmer
- Irene Kelley, American country and bluegrass singer
- Irene Keng, American actress
- Irene Kepl (born 1982), Austrian violinist and composer
- Irene Kerwin (1925–2023), American baseball player
- Irene Khan (born 1956), Bangladeshi academic
- Irene Kim (born 1987), Korean-American model and television personality
- Irene Kirpal (1886–1977), Czechoslovakian politician
- Irene Kitchings (1908–1975), American musician and pianist
- Irene Koh (born 1990), comics artist
- Irene de Kok (born 1963), Dutch judoka
- Irene Kopelman, Argentine-Dutch artist
- Irene Koss (1928–1996), German actress and presenter
- Irene Kotowicz (1919–2002), American baseball player
- Irene Koumarianou (1931–2013), Greek actress
- Irene Kowaliska (1905–1991), Italian painter, ceramicist and fabric designer
- Irene Kral (1932–1978), American jazz musician
- Irene Krugman (1925–1982), American sculptor
- Irene Krugman Rudnick (1929–2019), American politician
- Irene Corbally Kuhn (1898–1995), American journalist and author
- Irene Küng, Swiss photographer
- Irene Kuo (1919–1993), Chinese-American chef and bookwriter
- Irene Kuzemko, intersex activist
- Irene Kwambai (born 1978), Kenyan long-distance runner
- Irene Kwok (born 1933), Hong Kong swimmer
- Irene Lalji (died 2021), Surinamese lawyer and television presenter
- Irène Landau, French parasitologist
- Irene Lardschneider (born 1998), Italian biathlete
- Irene Larsen (1936–2016), co-founder of the Magic Castle and the Academy of Magical Arts
- Irene Latham (born 1971), American author
- Irène Laure (1898–1987), French socialist activist and politician
- Irene Heng Lauvsnes (born 1968), Norwegian politician
- Irene Leache (1839–1900), American teacher
- Irene Leigh, British dermatologist
- Irene Lemos, British classical archaeologist
- Irene Lentle (1912–2003), British table tennis player
- Irene Lentz (1901–1962), American fashion and film costume designer, known simply as "Irene"
- Irene Leverton (1927–2017), American pilot
- Irene Lewisohn (1886–1944), American philanthropist
- Irene Li, Boston based chef and restaurateur
- Irène Lidova, (1907–2002), Russian-French dance critic
- Irene Lieblich (1923–2008), Polish-American painter
- Irene Lim, several people
- Irene Lindh (born 1945), Swedish actress and singer
- Irène de Lipkowski (1898–1995), French politician
- Irene Lisboa (1892–1958), Portuguese novelist
- Irene Logan (born 1984), Liberian-Ghanaian singer
- Irene Loizate (born 1995), Spanish cyclist
- Irene D. Long (1950–2020), American aerospace physician
- Irene Longman (1877–1964), Australian politician
- Irene López, Spanish footballer
- Irene Loughlin (born 1967), Canadian artist
- Irene Lozano (born 1971), Spanish writer and journalist
- Irene Lusztig (born 1974), British-American filmmaker
- Irene Luxbacher (born 1970), Canadian artist, author and illustrator
- Irene MacDonald (1931–2002), Canadian diver
- Irene Maguire (1929–2016), American figure skater
- Irène Major (born 1979), British-Cameroonian fashion model and musical artist
- Irene Rima Makaryk, Canadian English-language academic
- Irene Mambilima (1952–2021), 7th Chief Justice of Zambia
- Irene Manjeri, Ugandan pastor
- Irene Mann (1929–1996), German dancer, actress and choreographer
- Irene Manning (1912–2004), American actress and singer
- Irene Manton (1904–1988), British botanist
- Irene Marcos (born 1960), Filipino exile
- Irene Marcuse, American author of mystery novels
- Irene Martínez (1944–2014), Cuban track and field athlete
- Irene Martínez (gymnast) (born 1966), Spanish gymnast
- Irene Mathyssen (born 1951), Canadian politician
- Irene Mawela (born 1940), South African singer and composer
- Irene Mawer, English educator
- Irene McAra-McWilliam, British design researcher and Director of the Glasgow School of Art
- Irene McCormack (1938–1991), Australian Catholic Sister murdered by guerrillas in Peru
- Irene McCulloch (1885–1987), American marine biologist of the 20th century
- Irene McFarland, American aviator
- Irene McGee, American podcaster
- Irene McGugan (born 1952), Scottish politician
- Irene McKinney (1939–2012), American poet
- Irene R. McLeod (1891–c. 1968), British poet, writer and editor
- Irene Mecchi (born 1949), American screenwriter and playwright
- Irene Meichsner, German science journalist and author
- Irène Mélikoff (1917–2009), Russian-French Turkologist
- Irene Miguel-Aliaga, Spanish-British physiologist
- Irene de Miguel (born 1981), Spanish politician
- Irene Miguélez, Spanish footballer
- Irene Mihalic (born 1976), German politician
- Irene Miller, British screenwriter
- Irene Miracle (born 1954), American actress
- Irene Mitchell, Australian actress and theatre director
- Irene Mitterstieler (born 1974), Italian luger
- Irene Mogaka (born 1985), Kenyan long-distance runner
- Irene Moillen, Swiss para-alpine skier
- Irène Molitor (1927–2018), Swiss alpine skier
- Irene Molloy (born 1978), American actress, singer and songwriter
- Irene Molyneux (1923–2019), English lawn bowls player
- Irene Monaco, Italian Paralympic competitor
- Irène Monesi, French writer
- Irene Montalà (born 1976), Spanish actress
- Irene Montero (born 1988), Spanish politician and psychologist
- Irene Montie (1921–2018), American statistician
- Irene Montrucchio (born 1991), Spanish synchronized swimmer
- Irene Moon, American entomologist and musician
- Irene Moorman Blackstone (1872–1944), African-American businesswoman and club member
- Irene Moors (born 1967), Dutch singer and television presenter
- Irene Morales (1865–1890), Chilean soldier
- Irene Moreira (born 1964), Uruguayan lawyer, businesswoman and politician
- Irene Moreno (born 1952), American rower
- Irene Morgan (1917–2007), African-American anti-segregation activist
- Irene Moroz, British applied mathematician
- Irene Morra (1893–1978), American film editor
- Irene Moss (born 1948), Australian solicitor and public servant
- Irene Mossop (1904–1988), British writer
- Irene Mounce, Canadian mycologist
- Irene Mountbatten, Marchioness of Carisbrooke (1890–1956), British noblewoman
- Irene Mullen (1914–1981), Canadian swimmer
- Irene Müller (born 1942), East German pair skater
- Irene Muloni (born 1960), Ugandan politician
- Irene Mulvey, American mathematician
- Irene Mulyagonja, Ugandan lawyer and judge
- Irene Patricia Murphy Keeley (born 1944), American judge
- Irene Mutsila (1949–2017), South African politician
- Irene Koki Mutungi (born 1976), Kenyan aviator
- Irene Muyanga (born 1943), Ugandan sprinter
- Irene Zin Mar Myint (born 1990), Burmese pop singer
- Irene Napier (born 1953), Scottish makeup designer
- Irene Jai Narayan (1932–2011), Fijian politician
- Irene Natividad (born 1948), Filipino-American women’s rights activist
- Irene Neal, American painter
- Irene Nelson (born 1972), Russian singer, songwriter and record producer
- Irene Neverla, Austrian professor
- Irene Ng (politician) (born 1963), Singaporean politician
- Irene Ng (born 1974), former American actor
- Irene Mrembo Njoki, Kenyan politician
- Irene Lange Nordahl (born 1968), Norwegian politician
- Irene Nordli (born 1967), Norwegian artist
- Irene Ntale (born 1989), Ugandan musician
- Irene Núñez (born 1987), Panamanian model and beauty pageant titleholder
- Irene Obera (born 1933), American track and field athlete
- Irene Oguiza (born 2000), Spanish footballer
- Irene Ogus, English table tennis player
- Irene Ogutu (born 1987), Kenyan footballer
- Irene Ojala (born 1960), Norwegian politician
- Irene Oldfather (born 1954), Scottish politician
- Irene Gut Opdyke (1918–2003), Polish Righteous Among the Nations
- Irene Osgood (1875–1922), American poet
- Irene Otieno (born 1986), American football player
- Irene Ovonji-Odida (born 1964), Ugandan lawyer, politician, and women's rights activist
- Irene Pacheco (born 1971), Colombian boxer
- Irene Papas (1929–2022), Greek actress
- Irene Paredes (born 1991), Spanish footballer
- Irene Parenti Duclos (1754–1795), Italian artist
- Irene Parlby (1868–1965), Canadian politician
- Irene E. Parmelee (1847–1934), American painter
- Irene Levine Paull (1908–1981), American writer and labor activist
- Irene Pavloska, American opera singer
- Irene Bowder Peacock (1892–1978), South African tennis player
- Irene C. Peden (born 1925), American engineer
- Irene Peirano Garrison, American philologist
- Irene Pepperberg (born 1949), American scientist noted for her studies in animal cognition
- Irene Pérez, Chicana muralist
- Irene Perveen (born 1940), Pakistani film playback singer
- Irene Peslikis (1943–2002), American feminist artist and activist
- Irene de Peyré (1874–1968), Guatemalan educator and feminist
- Irene Pijoan (1953–2004), Swiss-born American painter, sculptor, and educator
- Irene Flunser Pimentel (born 1950), Portuguese historian of the 20th century
- Irene Piotrowski (1941–2020), Lithuanian-Canadian athlete
- Irene Pirie (1914–1998), Canadian swimmer
- Irène Pittelioen (1927–2011), French gymnast
- Irene Pivetti (born 1963), Italian politician
- Irene Pnevmatikos, Australian politician
- Irene Pollin (1924–2020), American sports executive
- Irene Polo (1909–1942), Spanish journalist, publicist and translator
- Irène Popard (1894–1950), French choreographer
- Irène Possemiers (born 1934), Belgian swimmer
- Irene Prador (1911–1996), Austrian actress and writer
- Irene Prescott (born 1994), Tongan swimmer
- Irini Psyhrami, Greek pop singer
- Irene Purcell (1896–1972), American actress
- Irène Pusterla (born 1988), Swiss long jumper
- Irene Rathbone (1892–1980), novelist
- Irene Ravache (born 1944), Brazilian actress
- Irene Victoria Read, Australian charity and community worker
- Irene Reed (1931–2005), American anthropologist, linguist and educator
- Irene Reid (1930–2008), American jazz singer
- Irene Reyes-Noguerol, Spanish writer
- I. Rice Pereira (1902–1971), American abstract artist, poet and philosopher
- Irene Rich (1891–1988), American actress
- Irene Richards, New Zealand painter
- Irene Rigau (born 1951), Spanish politician
- Irene del Río, Spanish footballer
- Irene Roberts (born 1983), American mezzo-soprano
- Irene Robertson (1931–1994), American hurdler
- Irene Robledo (1890–1988), Mexican educator and humanist
- Irene Rocas i Romaguera, Catalan folklorist and lexicographer
- E. Irene Rood (1843-1921), founder of the Chicago Audubon Society
- Irene Rooke (1874–1958), English actress
- Irene Rosenfeld (born 1953), American businesswoman
- Irene Rousseau (born 1941), American artist
- Irene S. Rubin (born 1945), American political scientist
- Irene Ruhnke (1920–1999), baseball player
- Irene Runge (born 1942), American-German-Jewish sociologist and writer
- Irene E. Ryan (1909–1997), American aviator, engineer, geologist, government official and politician
- Irene Ryan (1902–1973), American actress
- Irene Ryder, Hong Kong musical artist
- Irene Sabadini, Italian mathematician
- Irene Sabatini, Zimbabwean writer
- Irene Sabido, Mexican producer and writer
- Irene Saez (born 1961), Venezuelan politician and former Miss Universe
- Irene Salemka (1931–2017), Canadian opera singer
- Irene Saltern (1911–2005), American designer
- Irene Sánchez-Escribano (born 1992), Spanish athletics competitor
- Irene Sandiford-Garner (born 1961), Barbadian politician
- Irene Sänger-Bredt (1911–1983), German engineer, mathematician and physicist
- Irene Sankoff, Canadian librettist and composer
- Irene Santiago, Filipina peace negotiator and women’s advocate
- Irene Sargent (1852–1932), American art historian
- Irene Saunders, American lexicographer
- Irene Savidge (1905–1985), English factory worker and subject of police interrogation scandal
- Irene Scharrer (1888–1971), English classical pianist
- Irene Schloss, Argentine Antarctic researcher
- Irene Schmidt, Dutch para table tennis player
- Irene H. Schöne (born 1942), German environmental economist
- Irene Schoof, Dutch cricketer
- Irene Schori (born 1983), Swiss curler
- Irene Schouten (born 1992), Dutch speed skater
- Irene Schroeder (1909–1931), American murderer
- Irene Schuch (1935–2023), German discus thrower
- Irène Schweizer (1941–2024), Swiss pianist
- Irene Sciriha, Maltese mathematician
- Irene F. Scott (1912–1997), American Tax Court judge
- Irene Scruggs (1901–1981), American singer
- Irene Mayer Selznick (1907–1990), American theatre producer
- Irene Sewankambo, Ugandan electrical engineer
- Irene Sharaff (1910–1993), American costume designer
- Irene Shepard (1922–2014), American politician
- Irene Shin, Virginia politician
- Irene Shubik (1929–2019), British television producer and story editor
- Irene Siegel, American artist
- Irene Siragusa (born 1993), Italian sprinter
- Irene Skliva (born 1978), Miss World 1996
- Iréne Slättengren (born 1952), Swedish equestrian
- Irene Sloan (1942–2008), American journalist
- Irene Smart (1921–2017), American politician
- Irene Solà (born 1990), Spanish writer and an artist
- Irene Spencer (1937–2017), American author
- Irene di Spilimbergo (1538–1559), Italian painter
- Irene Spry (1907–1998), Canadian economist
- Irene Staunton, Zimbabwean publisher and editor
- Irène Stecyk (born 1937), Belgian writer
- Irene Steer (1889–1977), British swimmer
- Irene Stefani (1891–1930), 20th-century Italian Catholic religious sister
- Irene Stegun (1919–2008), American politician
- Irene Stelling (born 1971), Danish footballer
- Irene Monat Stern, Polish-American painter
- Irene Steyn (born 1977), Namibian cyclist
- Irene Stoehr (1941–2023), German journalist
- Irene Stolofsky (1896–1950), American violinist
- Irene Strong (1929–2018), Canadian swimmer
- Irene Strychalski, American comic book writer
- Irene Kharisma Sukandar (born 1992), Indonesian chess player
- Irene Sunters (1928–2005), Scottish actress
- Irene Sutcliffe (1924–2019), English actress
- Irène Sweyd (born 1940), Belgian swimmer
- Irene Barnes Taeuber (1906–1974), American demographer
- Irene Tamborra, Italian particle astrophysicist
- Irene Tarimo (born 1964), Tanzanian scientist, biologist and educator
- Irene Frances Taylor (1890–1933), Australian journalist and activist
- Irene S. Taylor (1902–1989), American journalist and public information specialist
- Irene Taylor (1906–1988), American singer
- Irene Taylor (filmmaker) (born 1970), American director and producer
- Irene Tedrow (1907–1995), American character actress
- Irini Terzoglou (born 1979), Greek shot putter
- Irene Thomas (1920–2001), British radio personality
- Irène Tiendrébéogo (born 1977), Burkinabé-Monegasque athlete
- Irene Tinagli (born 1974), Italian economist and politician
- Irene Tinker (born 1927), American economist
- Irene Tobar (born 1989), Ecuadorian footballer
- Irène Tolleret (born 1967), French politician
- Irene Tomaszewski, Canadian writer, editor and translator
- Irene Naa Torshie Addo (born 1970), Ghanaian politician and lawyer
- Irene Tracey (born 1966), British neuroscientist
- Irène de Trebert (1921–1996), French singer, dancer and actress
- Irene Treppler (1926–2012), American politician
- Irene Triplett (1930–2020), last recipient of an American Civil War pension
- Irene Tripod, British actress
- Irene Trowell-Harris (born 1939), United States Air Force general
- Irene Tsu (born 1945), American actress
- Irene Tu, American comedian, actor and writer
- Irene Tucker, American literary critic and theorist
- Irène Tunc (1935–1972), French actress
- Irene Tupuna, Cook Islander lawn bowler
- Irene Uchida (1917–2013), Canadian scientist and Down Syndrome researcher
- Irene Usabiaga (born 1993), Spanish cyclist
- Irene Uwoya (born 1988), Tanzanian actress and businesswoman
- Irene Vallejo (born 1979), Spanish writer and academic
- Irene van den Broek (born 1980), Dutch cyclist
- Irene van Dyk (born 1972), New Zealand netball player
- Irene van der Reijken, Dutch athlete
- Irene van Renswoude, Dutch historian
- Irene van Zyl (born 1984), Namibian cricketer
- Irene Vanbrugh (1872–1949), English actress
- Irene Vecchi (born 1989), Italian fencer
- Irene Vélez Torres, Minister of Mines and Energy of Colombia (2022–present)
- Irène Vernal (1912–2008), Belgian actress
- Irene Vernon (1922–1998), American actress
- Irene Sue Vernon, American professor
- Irene Viaene (born 1949), Argentine alpine skier
- Irene Vilar, Puerto Rican writer
- Irene Villa (born 1978), Spanish author and journalist
- Irene Visedo (born 1978), Spanish actress
- Irene B. Vogel, American linguist
- Irene von Chavanne (1863–1938), Austrian opera singer
- Irene von Fladung, Austrian opera singer
- Irene von Meyendorff (1916–2001), Russian-born German-British actress
- Irene Vorrink (1918–1996), Dutch politician
- Irene Wagner-Döbler, German microbiologist
- Irene Wan (born 1966), Hong Kong actress and singer
- Irene Wang (born 1986), Hong Kong model and actress
- Irene Ward (1895–1980), British Conservative Party politician
- Irene Ware (1910–1993), American actress
- Irene N. Watts (1931–2023), German-born Canadian writer and educator
- Irene Weir, American artist and art educator
- Irene Wellington (1904–1984), British calligrapher and teacher
- Irene Whittome (born 1942), Canadian multimedia artist
- Irene Williams, American artist
- Irene J. Winter (born 1940), American art historian
- Irene Woodall (1946–2015), American journalist
- Irene Worth (1916–2002), American actress
- Irene Wosikowski (1910–1944), German political activist
- Irene Wrenner, American politician
- Irene Aloha Wright (1879–1972), American historian
- Irene Xavier (born 1951), Malaysian activist
- Irene Yah-Ling Sun, American actor and collector
- Irene Young Mattox (1881–1970), American Christian speaker and educator
- Irene Vera Young (1895–1975), Australian dancer and dance educator
- Irene Zazians (1927–2012), Iranian actress
- Irene Zechner, Austrian luger
- Irena Zemanová (born 1977), Czech figure skater
- Irène Zilahy (1904–1944), Hungarian actress
- Irene Zisblatt (born 1929), Carpathian-American Holocaust survivor
- Irene M. Zoppi (born 1966), Brigadier General, United States Army Reservist
- Irene Zundel, Mexican sculptor, painter and photographer
- Irène Zurkinden (1909–1987), Swiss painter
- Mother Irini (1936–2006), Egyptian abbess
Gauche, Isebell (3 February 2012). The A to Z of Names (Revised and Expanded Edition): Discover the Promise Your Name Holds!. Struik Christian Media. ISBN 978-1-4153-1626-9.
