Etonitazepipne (N-piperidino etonitazene) is a benzimidazole derivative with opioid effects around 100 times more potent than morphine,[1][2] which has been sold over the internet as a designer drug.[3][4][5][6]
Quick Facts Legal status, Identifiers ...
Etonitazepipne |
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2-[(4-Ethoxyphenyl)methyl]-5-nitro-1-(2-piperidin-1-ylethyl)benzimidazole
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Formula | C23H28N4O3 |
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Molar mass | 408.502 g·mol−1 |
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CCOC1=CC=C(C=C1)CC2=NC3=C(N2CCN4CCCCC4)C=CC(=C3)[N+](=O)[O-]
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InChI=1S/C23H28N4O3/c1-2-30-20-9-6-18(7-10-20)16-23-24-21-17-19(27(28)29)8-11-22(21)26(23)15-14-25-12-4-3-5-13-25/h6-11,17H,2-5,12-16H2,1H3 Key:UMGXRAISFRUVKD-UHFFFAOYSA-N
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Hunger A, Kebrle J, Rossi A, Hoffmann K (1960). "Benzimidazol-Derivate und verwandte Heterocyclen III. Synthese von 1-Aminoalkyl-2-benzyl-nitro-benzimidazolen". Helvetica Chimica Acta. 43 (4): 1032–1046. doi:10.1002/hlca.19600430412.
Berardinelli D, Taoussi O, Carlier J, Tini A, Zaami S, Sundermann T, et al. (July 2024). "In vitro, in vivo metabolism and quantification of the novel synthetic opioid N-piperidinyl etonitazene (etonitazepipne)". Clinical Chemistry and Laboratory Medicine. 62 (8): 1580–1590. doi:10.1515/cclm-2023-1360. PMID 38311816.
Vandeputte MM, Verougstraete N, Walther D, Glatfelter GC, Malfliet J, Baumann MH, et al. (June 2022). "First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass". Archives of Toxicology. 96 (6): 1865–1880. doi:10.1007/s00204-022-03294-2. hdl:1854/LU-8751259. PMID 35449307. S2CID 253718213.