Dimethylphenylpiperazinium

Dimethylphenylpiperazinium (DMPP) is a nicotinic acetylcholine receptor agonist which is selective for the ganglionic subtype.^[1] One of the earliest reports on the pharmacology of DMPP, describing it as a ganglion-stimulating, hypertensive agent, came from Graham Chen and his co-workers at Parke, Davis & Co. (Now Pfizer)^[2]

Dimethylphenylpiperazinium

Identifiers
IUPAC name 1,1-Dimethyl-4-phenylpiperazin-1-ium
CAS Number	114-28-3 N
PubChem CID	1316
IUPHAR/BPS	3967
ChemSpider	1276 Y
UNII	2FLS86GK2A
ChEMBL	ChEMBL134752 Y
CompTox Dashboard (EPA)	DTXSID10150626
Chemical and physical data
Formula	C12H19N2
Molar mass	191.298 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[N+]1(CCN(CC1)C2=CC=CC=C2)C
InChI InChI=1S/C12H19N2/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12/h3-7H,8-11H2,1-2H3/q+1 Y Key:MKGIQRNAGSSHRV-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

See also

• Phenylpiperazine

References

1. Prado WA, Segalla DK (August 2004). "Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats". Brain Research. 1018 (2): 272–82. doi:10.1016/j.brainres.2004.05.085. PMID 15276888. S2CID 45145197.
2. Chen G, Portman R, Wickel A (November 1951). "Pharmacology of 1,1-dimethyl-4-phenylpiperazinium iodide, a ganglion stimulating agent". The Journal of Pharmacology and Experimental Therapeutics. 103 (3): 330–6. PMID 14898449.