Phenylpiperazine

1-Phenylpiperazine is a simple chemical compound featuring a phenyl group bound to a piperazine ring. The suffix ‘-piprazole’ is sometimes used in the names of drugs to indicate they belong to this class.^[1]

Phenylpiperazine

Names
Preferred IUPAC name 1-Phenylpiperazine
Identifiers
CAS Number	92-54-6 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL9434 Y
ChemSpider	6829 Y
ECHA InfoCard	100.001.969
PubChem CID	7096
UNII	J9225CBI7D Y
CompTox Dashboard (EPA)	DTXSID8057855
InChI InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 Y Key: YZTJYBJCZXZGCT-UHFFFAOYSA-N Y
SMILES c1cc(ccc1)N2CCNCC2
Properties
Chemical formula	C10H14N2
Molar mass	162.23 g/mol
Appearance	clear colourless to yellow liquid
Density	1.028g/cm3
Melting point	18.8 °C (65.8 °F; 291.9 K)
Boiling point	287.2 °C (549.0 °F; 560.3 K) at 760mmHg
Solubility in water	insoluble
Hazards
Flash point	138.3 °C (280.9 °F; 411.4 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

1-Phenylpiperazine is toxic, its oral LD50 in rats is 210 mg/kg.^[2]

See also

• Substituted piperazine
• Serotonin antagonist and reuptake inhibitor
• Benzylpiperazine
• Diphenylpiperazine
• Diphenylmethylpiperazine
• Pyridinylpiperazine
• Pyrimidinylpiperazine

References

1. World Health Organization (WHO) (2006). "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). Archived from the original (PDF) on 2008-12-14. Retrieved 27 April 2010.
2. "1-Phenylpiperazine". pubchem.ncbi.nlm.nih.gov.

External links

• Media related to Phenylpiperazine at Wikimedia Commons