California Proposition 65 list of chemicals
Chemicals regulated in the United States From Wikipedia, the free encyclopedia
The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of January 3, 2020.[1] As a result of lawsuits, the list also contains substances known only to cause cancer in animals.[2]
This list is not exhaustive, as the complete list contains over 900 chemicals.[2]
Chemicals currently listed under California Proposition 65
Summarize
Perspective
 | Parts of this article (those related to California Proposition 65 list of chemicals) need to be updated. (November 2024) |
| Substance | Reason | CAS Registry Number † | Date Listed |
|---|---|---|---|
| A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) | Cancer | 26148-68-5 | January 1, 1990 |
| 1,4-Dichloro-2-nitrobenzene | Cancer | 89-61-2 | September 13, 2019 |
| p-chloro-α,α,α-trifluorotoluene (para-Chlorobenzotrifluoride, PCBTF) | Cancer | 98-56-6 | June 28, 2019 |
| Bevacizumab | Developmental
Reproductive toxicity (female, male) |
216974-75-3 | March 8, 2019 |
| Aflatoxins | Cancer | --- | January 1, 1988 |
| Ceramic fibers (airborne particles of respirable size) | Cancer | --- | February 27, 1987 |
| Certain combined chemotherapy for lymphomas | Cancer | --- | February 27, 1987 |
| para-Nitroanisole | Cancer | 100-17-4 | September 13, 2019 |
| 2,4-Dichloro-1-nitrobenzene | Cancer | 611-06-3 | September 13, 2019 |
| Δ9-Tetrahydrocannabinol (Δ9-THC) | Developmental | January 3, 2020 | |
| 2-Chloronitrobenzene | Cancer | 88-73-3 | September 13, 2019 |
| 2-Amino-4-chlorophenol | Cancer | 95-85-2 | September 13, 2019 |
| Cannabis (marijuana) smoke | Developmental | --- | January 3, 2020 |
| Abiraterone acetate | Developmental
Reproductive toxicity (female, male) |
154229-18-2 | April 8, 2016 |
| Acetaldehyde | Cancer | 75-07-0 | April 1, 1988 |
| Acetamide | Cancer | 60-35-5 | January 1, 1990 |
| Acetazolamide | Developmental | 59-66-5 | August 20, 1999 |
| Acetochlor | Cancer | 34256-82-1 | January 1, 1989 |
| Acetohydroxamic acid | Developmental | 546-88-3 | April 1, 1990 |
| 2-Acetylaminofluorene | Cancer | 53-96-3 | July 1, 1987 |
| Acifluorfen sodium | Cancer | 62476-59-9 | January 1, 1990 |
| Acrylamide | Cancer
Developmental Reproductive toxicity (male) |
79-06-1 | January 1, 1990
February 25, 2011 |
| Acrylonitrile | Cancer | 107-13-1 | July 1, 1987 |
| Actinomycin D | Cancer
Developmental |
50-76-0 | October 1, 1989
October 1, 1992 |
| AF-2 ([2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide) | Cancer | 3688-53-7 | July 1, 1987 |
| Alachlor | Cancer | 15972-60-8 | January 1, 1989 |
| Alcoholic beverages
Alcoholic beverages, when associated with alcohol abuse |
Cancer | --- | April 29, 2011
July 1, 1988 |
| Aldrin | Cancer | 309-00-2 | July 1, 1988 |
| All-trans retinoic acid | Developmental | 302-79-4 | January 1, 1989 |
| Aloe vera, non-decolorized whole leaf extract | Cancer | – | December 4, 2015 |
| Alprazolam | Developmental | 28981-97-7 | July 1, 1990 |
| Altretamine | Developmental
Reproductive toxicity (male) |
645-05-6 | August 20, 1999 |
| Amantadine hydrochloride | Developmental | 665-66-7 | February 27, 2001 |
| Amikacin sulfate | Developmental | 39831-55-5 | July 1, 1990 |
| 2-Aminoanthraquinone | Cancer | 117-79-3 | October 1, 1989 |
| p-Aminoazobenzene | Cancer | 60-09-3 | January 1, 1990 |
| o-Aminoazotoluene | Cancer | 97-56-3 | July 1, 1987 |
| 4-Aminobiphenyl (4-amino-diphenyl) | Cancer | 92-67-1 | February 27, 1987 |
| 1-Amino-2,4-dibromoanthraquinone | Cancer | 81-49-2 | August 26, 1997 |
| 3-Amino-9-ethylcarbazole hydrochloride | Cancer | 6109-97-3 | July 1, 1989 |
| 2-Aminofluorene | Cancer | 153-78-6 | January 29, 1999 |
| Aminoglutethimide | Developmental | 125-84-8 | July 1, 1990 |
| Aminoglycosides | Developmental | – | October 1, 1992 |
| 1-Amino-2-methylanthraquinone (Disperse Orange 11) | Cancer | 82-28-0 | October 1, 1989 |
| 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | Cancer | 712-68-5 | July 1, 1987 |
| 4-Amino-2-nitrophenol | Cancer | 119-34-6 | January 29, 1999 |
| Aminopterin | Developmental
Reproductive toxicity (female) |
54-62-6 | July 1, 1987 |
| Amiodarone hydrochloride | Developmental
Reproductive toxicity (female, male) |
19774-82-4 | August 26, 1997 |
| Amitraz | Developmental | 33089-61-1 | March 30, 1999 |
| Amitrole | Cancer | 61-82-5 | July 1, 1987 |
| Amoxapine | Developmental | 14028-44-5 | May 15, 1998 |
| Amsacrine | Cancer | 51264-14-3 | August 7, 2009 |
| Anabolic steroids | Reproductive toxicity (female, male) | – | April 1, 1990 |
| Androstenedione | Cancer | 63-05-8 | May 3, 2011 |
| ACE inhibitors (Angiotensin converting enzyme) | Developmental | – | October 1, 1992 |
| Aniline | Cancer | 62-53-3 | January 1, 1990 |
| Aniline hydrochloride | Cancer | 142-04-1 | May 15, 1998 |
| o-Anisidine | Cancer | 90-04-0 | July 1, 1987 |
| o-Anisidine hydrochloride | Cancer | 134-29-2 | July 1, 1987 |
| Anisindione | Developmental | 117-37-3 | October 1, 1992 |
| Anthracene | Cancer | 120-12-7 | August 11, 2023 |
| Anthraquinone | Cancer | 84-65-1 | September 28, 2007 |
| Antimony oxide (Antimony trioxide) | Cancer | 1309-64-4 | October 1, 1990 |
| Aramite | Cancer | 140-57-8 | July 1, 1987 |
| Areca nut | Cancer | – | February 3, 2006 |
| Aristolochic acids | Cancer | – | July 9, 2004 |
| Arsenic (inorganic arsenic compounds) | Cancer | – | February 27, 1987 |
| Arsenic (inorganic oxides) | Developmental | – | May 1, 1997 |
| Asbestos | Cancer | 1332-21-4 | February 27, 1987 |
| Aspirin during the last three months of pregnancy | Developmental
Reproductive toxicity (female) |
50-78-2 | July 1, 1990 |
| Atenolol | Developmental | 29122-68-7 | August 26, 1997 |
| Atrazine | Developmental
Reproductive toxicity (female) |
1912-24-9 | July 15, 2016 |
| Auramine | Cancer | 492-80-8 | July 1, 1987 |
| Auranofin | Developmental | 34031-32-8 | January 29, 1999 |
| Avermectin B1 (Abamectin) | Developmental | 71751-41-2 | December 3, 2010 |
| Azacitidine | Cancer | 320-67-2 | January 1, 1992 |
| Azaserine | Cancer | 115-02-6 | July 1, 1987 |
| Azathioprine | Cancer
Developmental |
446-86-6 | February 27, 1987
September 1, 1996 |
| Azobenzene | Cancer | 103-33-3 | January 1, 1990 |
| Barbiturates | Developmental | – | October 1, 1992 |
| Beclomethasone dipropionate | Developmental | 5534-09-8 | May 15, 1998 |
| Benomyl | Developmental
Reproductive toxicity (male) |
17804-35-2 | July 1, 1991 |
| Benthiavalicarb-isopropyl | Cancer | 177406-68-7 | July 1, 2008 |
| Benz[a]anthracene | Cancer | 56-55-3 | July 1, 1987 |
| Benzene | Cancer
Developmental Reproductive toxicity (male) |
71-43-2 | February 27, 1987
December 26, 1997 |
| Benzidine (and its salts) | Cancer | 92-87-5 | February 27, 1987 |
| Benzidine-based dyes | Cancer | – | October 1, 1992 |
| Benzodiazepines | Developmental | – | October 1, 1992 |
| Benzo[b]fluoranthene | Cancer | 205-99-2 | July 1, 1987 |
| Benzo[j]fluoranthene | Cancer | 205-82-3 | July 1, 1987 |
| Benzo[k]fluoranthene | Cancer | 207-08-9 | July 1, 1987 |
| Benzofuran | Cancer | 271-89-6 | October 1, 1990 |
| Benzophenone | Cancer | 119-61-9 | |
| Benzo[a]pyrene | Cancer | 50-32-8 | |
| Benzotrichloride | Cancer | 98-07-7 | |
| Benzphetamine hydrochloride | Developmental | 5411-22-3 | |
| Benzyl chloride | Cancer | 100-44-7 | |
| Benzyl violet 4B | Cancer | 1694-09-3 | July 1, 1987 |
| Beryllium and beryllium compounds | Cancer | – | |
| Betel quid with tobacco | Cancer | – | |
| Betel quid without tobacco | Cancer | – | |
| 2,2-Bis(bromomethyl)-1,3-propanediol | Cancer | 3296-90-0 | |
| Bis(2-chloroethyl)ether | Cancer | 111-44-4 | |
| N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) | Cancer | 494-03-1 | |
| Bischloroethyl nitrosourea (BCNU, Carmustine) | Developmental | 154-93-8 | July 1, 1987 |
| Bis(chloromethyl)ether | Cancer | 542-88-1 | |
| Bis(2-chloro-1-methylethyl)ether | Cancer | – | |
| Bisphenol A (BPA) | Reproductive toxicity (female)
Developmental |
80-05-7 | May 11, 2015
December 18, 2020 |
| Bisphenol S | Reproductive toxicity (female, male) | 80-09-1 | December 29, 2023
January 3, 2025 |
| Bitumen, extracts of steam-refined and air refined | Cancer | – | |
| Bracken fern | Cancer | – | |
| Bromacil lithium salt | Developmental,
Reproductive toxicity (male) |
53404-19-6 | May 18, 1999
January 17, 2003 |
| Bromate | Cancer | 15541-45-4 | |
| Bromochloroacetic acid | Cancer | 5589-96-8 | |
| Bromodichloroacetic acid | Cancer | 71133-14-7 | |
| Bromodichloromethane | Cancer | 75-27-4 | |
| Bromoethane | Cancer | 74-96-4 | December 22, 2000 |
| Bromoform | Cancer | 75-25-2 | |
| 1-Bromopropane (1-BP) | Cancer
Developmental Reproductive toxicity (female, male) |
106-94-5 | August 5, 2016
December 7, 2004 |
| 2-Bromopropane (2-BP) | Cancer
Reproductive toxicity (female, male) |
75-26-3 | August 11, 2023
May 31, 2005 |
| 1-Bromo-3-chloropropane | Cancer | 109-70-6 | |
| Bromoxynil | Developmental | 1689-84-5 | October 1, 1990 |
| Bromoxynil octanoate | Developmental | 1689-99-2 | |
| Butabarbital sodium | Developmental | 143-81-7 | |
| 1,3-Butadiene | Cancer
Developmental Reproductive toxicity (female, male) |
106-99-0 | April 1, 1988
April 16, 2004 |
| 1,4-Butanediol dimethanesulfonate (Busulfan) | Cancer
Developmental |
55-98-1 | February 27, 1987
January 1, 1989 |
| 1-Butyl glycidyl ether | Cancer | 2426-08-6 | |
| Butylated hydroxyanisole | Cancer | 25013-16-5 | |
| Butyl benzyl phthalate (BBP) | Developmental | 85-68-7 | |
| beta-Butyrolactone | Cancer | 3068-88-0 | July 1, 1987 |
| Cacodylic acid | Cancer | 75-60-5 | |
| Cadmium and cadmium compounds | Developmental
Reproductive toxicity (male) Cancer |
– | May 1, 1997
October 1, 1987 |
| Caffeic acid | Cancer | 331-39-5 | |
| Captafol | Cancer | 2425-06-1 | |
| Captan | Cancer | 133-06-2 | |
| Carbamazepine | Developmental | 298-46-4 | |
| Carbaryl | Cancer
Developmental Reproductive toxicity (female, male) |
63-25-2 | February 5, 2010
August 7, 2009 |
| Carbazole | Cancer | 86-74-8 | |
| Carbon black (airborne, unbound particles of respirable size) | 1333-86-4 | ||
| Carbon-black extracts | Cancer | --- | January 1, 1990 |
| Carbon disulfide | 75-15-0 | ||
| Carbon monoxide | 630-08-0 | ||
| Carbon tetrachloride | 56-23-5 | ||
| Carboplatin | 41575-94-4 | ||
| N-Carboxymethyl-N-nitrosourea | 60391-92-6 | ||
| Catechol | 120-80-9 | ||
| Chenodiol | 474-25-9 | ||
| Chloral | 75-87-6 | ||
| Chloral hydrate | 302-17-0 | ||
| Chlorambucil | 305-03-3 | ||
| Chloramphenicol sodium succinate | 982-57-0 | ||
| Chlorcyclizine hydrochloride | Developmental | 1620-21-9 | July 1, 1987 |
| Chlordane | 57-74-9 | ||
| Chlordecone (Kepone) | 143-50-0 | ||
| Chlordiazepoxide | 58-25-3 | ||
| Chlordiazepoxide hydrochloride | 438-41-5 | ||
| Chlordimeform | 6164-98-3 | ||
| Chlorendic acid | 115-28-6 | ||
| Chlorinated paraffins (Avg. chain length C12; approx. 60 percent chlorine by weight) | 108171-26-2 | ||
| p-Chloroaniline | 106-47-8 | ||
| p-Chloroaniline hydrochloride | 20265-96-7 | ||
| Chloroethane | 75-00-3 | ||
| 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, Lomustine) | 13010-47-4 | ||
| 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) | 13909-09-6 | ||
| Chloroform | 67-66-3 | ||
| Chloromethyl methyl ether | 107-30-2 | ||
| 3-Chloro-2-methylpropene | 563-47-3 | ||
| 1-Chloro-4-nitrobenzene | 100-00-5 | ||
| 4-Chloro-o-phenylenediamine | 95-83-0 | ||
| Chloroprene | 126-99-8 | ||
| 2-Chloropropionic acid | 598-78-7 | ||
| Chlorothalonil | 1897-45-6 | ||
| p-Chloro-o-toluidine | 95-69-2 | ||
| Strong acid salts of p-Chloro-o-toluidine | – | ||
| 5-Chloro-o-toluidine and its strong acid salts | 95-79-4 | ||
| Chlorotrianisene | 569-57-3 | ||
| Chlorozotocin | 54749-90-5 | ||
| Chlorpyrifos | 2921-88-2 | ||
| Chrysene | 218-01-9 | ||
| C.I. Acid Red 114 | 6459-94-5 | ||
| C.I. Basic Red 9 monohydrochloride | 569-61-9 | ||
| C.I. Direct Blue 15 | 2429-74-5 | ||
| C.I. Direct Blue 218 | 28407-37-6 | ||
| C.I. Disperse Yellow 3 | 2832-40-8 | ||
| C.I. Solvent Yellow 14 | 842-07-9 | ||
| Ciclosporin (Cyclosporine, Cyclosporine A) | 59865-13-3; 79217-60-0 | ||
| Cidofovir | 113852-37-2 | ||
| Cinnamyl anthranilate | 87-29-6 | ||
| Cisplatin | 15663-27-1 | ||
| Citrus Red No. 2 | 6358-53-8 | ||
| Cladribine | 4291-63-8 | ||
| Clarithromycin | Developmental | 81103-11-9 | May 1, 1997 |
| Clobetasol propionate | 25122-46-7 | ||
| Clofibrate | 637-07-0 | ||
| Clomiphene citrate | 50-41-9 | ||
| Clorazepate dipotassium | 57109-90-7 | ||
| CMNP (pyrazachlor) | 6814-58-0 | ||
| Coal-tar pitch | – | ||
| Cobalt metal powder | 7440-48-4 | ||
| Cobalt(II) oxide | 1307-96-6 | ||
| Cobalt sulfate | 10124-43-3 | ||
| Cobalt sulfate heptahydrate | 10026-24-1 | ||
| Cocaine | 50-36-2 | ||
| Cocamide diethanolamine (Coconut oil diethanolamine condensate) | – | ||
| Codeine phosphate | 52-28-8 | ||
| Coke oven emissions | – | ||
| Colchicine | 64-86-8 | ||
| Conjugated estrogens | – | ||
| Creosotes | – | ||
| p-Cresidine | 120-71-8 | ||
| Cumene | 98-82-8 | ||
| Cupferron | 135-20-6 | ||
| Cyanazine | 21725-46-2 | ||
| Cycasin | 14901-08-7 | ||
| Cycloate | 1134-23-2 | ||
| Cycloheximide | 66-81-9 | ||
| Cyclopenta[cd]pyrene | 27208-37-3 | ||
| Cyclophosphamide | 50-18-0; 6055-19-2 | ||
| Cyhexatin | 13121-70-5 | ||
| Cytarabine | 147-94-4 | ||
| Cytembena | 21739-91-3 | ||
| D&C Orange No. 17 | Cancer | 3468-63-1 | |
| D&C Red No. 8 | Cancer | 2092-56-0 | October 1, 1990 |
| D&C Red No. 9 | Cancer | 5160-02-1 | |
| D&C Red No. 19 | Cancer | 81-88-9 | |
| Dacarbazine | 4342-03-4 | ||
| Daminozide | 1596-84-5 | ||
| Danazol | 17230-88-5 | ||
| Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) | 117-10-2 | ||
| Daunomycin | 20830-81-3 | ||
| Daunorubicin hydrochloride | 23541-50-6 | ||
| 2,4-D butyric acid | 94-82-6 | ||
| DDD (Dichlorodiphenyl-dichloroethane) | 72-54-8 | ||
| DDE (Dichlorodiphenyl-dichloroethylene) | 72-55-9 | ||
| DDT (Dichlorodiphenyl-trichloroethane) | 50-29-3 | ||
| o,p'-DDT | 789-02-6 | ||
| p,p'-DDT | 50-29-3 | ||
| DDVP (Dichlorvos) | 62-73-7 | ||
| Demeclocycline hydrochloride | 64-73-3 | ||
| Des-ethyl atrazine (DEA) | 6190-65-4 | ||
| Des-isopropyl atrazine (DIA) | 1007-28-9 | ||
| N,N'-Diacetylbenzidine | 613-35-4 | ||
| 2,4-Diaminoanisole | Cancer | 615-05-4 | October 1, 1990 |
| 2,4-Diaminoanisole sulfate | 39156-41-7 | ||
| 2,4-Diamino-6-chloro-s-triazine (DACT) | 3397-62-4 | ||
| 4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) | 101-80-4 | ||
| 2,4-Diaminotoluene | 95-80-7 | ||
| Diazepam | 439-14-5 | ||
| Diazoaminobenzene | 136-35-6 | ||
| Diazoxide | 364-98-7 | ||
| Dibenz[a,h]acridine | 226-36-8 | ||
| Dibenz[a,j]acridine | 224-42-0 | ||
| Dibenzanthracenes | – | ||
| Dibenz[a,c]anthracene | 215-58-7 | ||
| Dibenz[a,h]anthracene | 53-70-3 | ||
| Dibenz[a,j]anthracene | 224-41-9 | ||
| 7H-Dibenzo[c,g]carbazole | 194-59-2 | ||
| Dibenzo[a,e]pyrene | 192-65-4 | ||
| Dibenzo[a,h]pyrene | 189-64-0 | ||
| Dibenzo[a,i]pyrene | 189-55-9 | ||
| Dibenzo[a,l]pyrene | 191-30-0 | ||
| Dibromoacetic acid | 631-64-1 | ||
| Dibromoacetonitrile | 3252-43-5 | ||
| 1,2-Dibromo-3-chloropropane (DBCP) | Cancer | 96-12-8 | July 1, 1987 |
| 2,3-Dibromo-1-propanol | 96-13-9 | ||
| Dichloroacetic acid | 79-43-6 | ||
| p-Dichlorobenzene | 106-46-7 | ||
| 3,3'-Dichlorobenzidine | 91-94-1 | ||
| 3,3'-Dichlorobenzidine dihydrochloride | 612-83-9 | ||
| 1,4-Dichloro-2-butene | 764-41-0 | ||
| 3,3'-Dichloro-4,4'-diamino-diphenyl ether | 28434-86-8 | ||
| 1,1-Dichloroethane | 75-34-3 | ||
| Dichloromethane (Methylene chloride) | 75-09-2 | ||
| Dichlorophene | 97-23-4 | ||
| Dichlorphenamide | 120-97-8 | ||
| 1,2-Dichloropropane | 78-87-5 | ||
| 1,3-Dichloro-2-propanol (1,3-DCP) | 96-23-1 | ||
| 1,3-Dichloropropene | 542-75-6 | ||
| Diclofop methyl | 51338-27-3 | ||
| Dicumarol | 66-76-2 | ||
| Dieldrin | 60-57-1 | ||
| Diepoxybutane | 1464-53-5 | ||
| Diesel engine exhaust | Cancer | – | October 1, 1990 |
| Diethanolamine | 111-42-2 | ||
| Di(2-ethylhexyl)phthalate (DEHP) | 117-81-7 | ||
| 1,2-Diethylhydrazine | 1615-80-1 | ||
| Diethylstilbestrol (DES) | Cancer
Developmental |
56-53-1 | February 27. 1987
July 1, 1987 |
| Diethyl sulfate | 64-67-5 | ||
| Diflunisal | 22494-42-4 | ||
| Diglycidyl resorcinol ether (DGRE) | 101-90-6 | ||
| Dihydroergotamine mesylate | Develeopmental | 6190-39-2 | May 1, 1997 |
| Dihydrosafrole | 94-58-6 | ||
| Di-isodecyl phthalate (DIDP) | 68515-49-1/ 26761-40-0 | ||
| Diisononyl phthalate (DINP) | – | ||
| Diisopropyl sulfate | 2973-10-6 | ||
| Diltiazem hydrochloride | 33286-22-5 | ||
| 3,3'-Dimethoxybenzidine (o-Dianisidine) | 119-90-4 | ||
| 3,3'-Dimethoxybenzidine dihydrochloride | Cancer | 20325-40-0 | October 1, 1990 |
| N,N-Dimethylacetamide | 127-19-5 | ||
| 4-Dimethylaminoazobenzene | 60-11-7 | ||
| trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole | 55738-54-0 | ||
| 7,12-Dimethylbenz[a]anthracene | 57-97-6 | ||
| 3,3'-Dimethylbenzidine (ortho-Tolidine) | 119-93-7 | ||
| 3,3'-Dimethylbenzidine dihydrochloride | 612-82-8 | ||
| Dimethylcarbamoyl chloride | 79-44-7 | ||
| 1,1-Dimethylhydrazine (UDMH) | 57-14-7 | ||
| 1,2-Dimethylhydrazine | 540-73-8 | ||
| Dimethyl hydrogen phosphite | 868-85-9 | ||
| 2,6-Dimethyl-N-nitrosomorpholine (DMNM) | 1456-28-6 | ||
| Dimethyl sulfate | 77-78-1 | ||
| N,N-Dimethyl-p-toluidine | 99-97-8 | ||
| Dimethylvinylchloride | 513-37-1 | ||
| Di-n-butyl phthalate (DBP) | 84-74-2 | ||
| Di-n-hexyl phthalate (DnHP) | 84-75-3 | ||
| m-Dinitrobenzene | 99-65-0 | ||
| o-Dinitrobenzene | 528-29-0 | ||
| p-Dinitrobenzene | 100-25-4 | ||
| 3,7-Dinitrofluoranthene | 105735-71-5 | ||
| 3,9-Dinitrofluoranthene | 22506-53-2 | ||
| 1,3-Dinitropyrene | 75321-20-9 | ||
| 1,6-Dinitropyrene | Cancer | 42397-64-8 | October 1, 1990 |
| 1,8-Dinitropyrene | 42397-65-9 | ||
| 2,4-Dinitrotoluene | 121-14-2 | ||
| 2,6-Dinitrotoluene | 606-20-2 | ||
| Dinitrotoluene | – | ||
| Dinocap | 39300-45-3 | ||
| Dinoseb | 88-85-7 | ||
| Di-n-propyl isocinchomeronate (MGK Repellent 326) | 136-45-8 | ||
| 1,4-Dioxane | 123-91-1 | ||
| Diphenylhydantoin (Phenytoin) | Cancer
Developmental |
57-41-0 | January 1, 1988
July 1, 1987 |
| Diphenylhydantoin sodium salt | Cancer | 630-93-3 | |
| Direct Black 38 | 1937-37-7 | ||
| Direct Blue 6 | 2602-46-2 | ||
| Direct Brown 95 | 16071-86-6 | ||
| Disodium cyanodithioimidocarbonate | 138-93-2 | ||
| Disperse Blue 1 | Cancer | 2475-45-8 | October 1, 1990 |
| Diuron | 330-54-1 | ||
| Doxorubicin hydrochloride (Adriamycin) | Cancer
Developmental Reproductive toxicity (male) |
25316-40-9 | July 1, 1987
January 29, 1999 |
| Doxycycline | 564-25-0 | ||
| Doxycycline calcium | 94088-85-4 | ||
| Doxycycline hyclate | 24390-14-5 | ||
| Doxycycline monohydrate | 17086-28-1 | ||
| Emissions from Combustion of coal | – | ||
| Emissions from high-temperature unrefined rapeseed oil | – | ||
| Endrin | 72-20-8 | ||
| Environmental tobacco smoke (ETS) | – | ||
| Epichlorohydrin | 106-89-8 | ||
| Epoxiconazole | 135319-73-2 | ||
| Ergotamine tartrate | 379-79-3 | ||
| Erionite | 12510-42-8; 66733-21-9 | ||
| Estradiol | 50-28-2 | ||
| Estragole | 140-67-0 | ||
| Estrogens (steroidal) | – | ||
| Estrone | 53-16-7 | ||
| Estropipate | 7280-37-7 | ||
| Ethanol in alcoholic beverages | – | ||
| Ethinylestradiol | 57-63-6 | ||
| Ethionamide | 536-33-4 | ||
| Ethoprop | 13194-48-4 | ||
| Ethyl acrylate | 140-88-5 | ||
| Ethylbenzene | 100-41-4 | ||
| Ethyl dipropylthiocarbamate | 759-94-4 | ||
| Ethyl-4,4'-dichlorobenzilate | 510-15-6 | ||
| Ethylene dibromide | Cancer
Developmental Reproductive toxicity (male) |
106-93-4 | July 1, 1987
May 15, 1998 |
| Ethylene dichloride (1,2-Dichloroethane) | 107-06-2 | ||
| Ethylene glycol (when ingested) | 107-21-1 | ||
| Ethylene glycol monoethyl ether | 110-80-5 | ||
| Ethylene glycol monoethyl ether acetate | 111-15-9 | ||
| Ethylene glycol monomethyl ether | 109-86-4 | ||
| Ethylene glycol monomethyl ether acetate | 110-49-6 | ||
| Ethyleneimine (Aziridine) | 151-56-4 | ||
| Ethylene oxide | Cancer
Reproductive toxicity (female) |
75-21-8 | July 1, 1987
February 27, 1987 |
| Ethylene thiourea | 96-45-7 | ||
| Ethyl methanesulfonate | 62-50-0 | ||
| Etodolac | 41340-25-4 | ||
| Etoposide | 33419-42-0 | ||
| Etoposide in combination with Cisplatin and Bleomycin | – | ||
| Etretinate | Developmental | 54350-48-0 | July 1, 1987 |
| Fenoxaprop ethyl | 66441-23-4 | ||
| Fenoxycarb | 72490-01-8 | ||
| Filgrastim | 121181-53-1 | ||
| Fluazifop butyl | 69806-50-4 | ||
| Flunisolide | 3385-03-3 | ||
| Fluoro-edenite fibrous amphibole | – | ||
| Fluorouracil | 51-21-8 | ||
| Fluoxymesterone | 76-43-7 | ||
| Flurazepam hydrochloride | 1172-18-5 | ||
| Flurbiprofen | 5104-49-4 | ||
| Flutamide | 13311-84-7 | ||
| Fluticasone propionate | 80474-14-2 | ||
| Fluvalinate | 69409-94-5 | ||
| Folpet | 133-07-3 | ||
| Formaldehyde (gas) | 50-00-0 | ||
| 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole | 3570-75-0 | ||
| Fumonisin B1 | 116355-83-0 | ||
| Furan | 110-00-9 | ||
| Furazolidone | 67-45-8 | ||
| Furfuryl alcohol | 98-00-0 | ||
| Furmecyclox | 60568-05-0 | ||
| Fusarin C | 79748-81-5 | ||
| Gallium arsenide | 1303-00-0 | ||
| Ganciclovir | 82410-32-0 | ||
| Ganciclovir sodium | 107910-75-8 | ||
| Gasoline engine exhaust (condensates/extracts) | Cancer | – | October 1, 1990 |
| Gemfibrozil | Cancer
Reproductive toxicity (female, male) |
25812-30-0 | December 22, 2000
August 20, 1999 |
| Gentian violet(Crystal violet) | 548-62-9 | ||
| Glass wool fibers (when inhalable and biopersistent) | – | ||
| Glu-P-1 (2-Amino-6-methyldipyrido[1,2- a:3',2'-d]imidazole) | 67730-11-4 | ||
| Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) | 67730-10-3 | ||
| Glycidaldehyde | 765-34-4 | ||
| Glycidol | 556-52-5 | ||
| Glycidyl methacrylate | 106-91-2 | ||
| Glyphosate | 1071-83-6 | ||
| Goldenseal root powder | – | ||
| Goserelin acetate | 65807-02-5 | ||
| Griseofulvin | 126-07-8 | ||
| Gyromitrin (Acetaldehyde methylformylhydrazone) | 16568-02-8 | ||
| Halazepam | 23092-17-3 | ||
| Halobetasol propionate | 66852-54-8 | ||
| Haloperidol | 52-86-8 | ||
| Halothane | 151-67-7 | ||
| HC Blue 1 | 2784-94-3 | ||
| Heptachlor | 76-44-8 | ||
| Heptachlor epoxide | 1024-57-3 | ||
| Herbal remedies containing plant species of the genus Aristolochia | – | ||
| Hexachlorobenzene | 118-74-1 | ||
| Hexachlorobutadiene | 87-68-3 | ||
| Hexachlorocyclohexane | – | ||
| Hexachlorodibenzodioxin | 34465-46- 8 | ||
| Hexachloroethane | 67-72-1 | ||
| 2,4-Hexadienal | – | ||
| Hexafluoroacetone | 684-16-2 | ||
| Hexamethylphosphoramide | 680-31-9 | ||
| n-Hexane | 110-54-3 | ||
| 2,5-Hexanedione | 110-13-4 | ||
| Hexavalent chromium | – | ||
| Histrelin acetate | – | ||
| Hydramethylnon | 67485-29-4 | ||
| Hydrazine | 302-01-2 | ||
| Hydrazine sulfate | 10034-93-2 | ||
| Hydrazobenzene (1,2-Diphenylhydrazine) | 122-66-7 | ||
| Hydrogen cyanide | 74-90-8 | ||
| 1-Hydroxyanthraquinone | Cancer | 129-43-1 | |
| Hydroxyurea | Developmental | 127-07-1 | May 1, 1997 |
| Idarubicin hydrochloride | 57852-57-0 | ||
| Ifosfamide | 3778-73-2 | ||
| Iodine-131 | 10043-66-0 | ||
| Imazalil | 35554-44-0 | ||
| Indeno[1,2,3-cd]pyrene | 193-39-5 | ||
| Indium phosphide | 22398-80-7 | ||
| Indium tin oxide | 50926-11-9 | ||
| IQ (2-Amino-3-methylimidazo[4,5-f] quinoline) | 76180-96-6 | ||
| Iprodione | 36734-19-7 | ||
| Iprovalicarb | 140923-17-7; 140923-25-7 | ||
| Iron dextran complex | 9004-66-4 | ||
| Isobutyl nitrite | 542-56-3 | ||
| Isoprene | 78-79-5 | ||
| Isopyrazam | 881685-58-1 | ||
| Isotretinoin | Developmental | 4759-48-2 | July 1, 1987 |
| Isoxaflutole | Cancer | 141112-29-0 | December 22, 2000 |
| Kresoxim-methyl | 143390-89-0 | ||
| Lactofen | 77501-63-4 | ||
| Lasiocarpine | 303-34-4 | ||
| Lead | 7439-92-1 | ||
| Lead and lead compounds | Cancer | – | |
| Lead acetate | Cancer | 301-04-2 | |
| Lead phosphate | Cancer | 7446-27-7 | |
| Lead subacetate | Cancer | 1335-32-6 | |
| Leather dust | Cancer | – | |
| Leuprolide acetate | 74381-53-6 | ||
| Levodopa | 59-92-7 | ||
| Levonorgestrel implants | 797-63-7 | ||
| Leucomalachite green | Cancer | 129-73-7 | |
| Lindane and other hexachlorocyclohexane isomers | Cancer | – | |
| Linuron | Developmental | 330-55-2 | |
| Lithium carbonate | Developmental | 554-13-2 | January 1, 1991 |
| Lithium citrate | Developmental | 919-16-4 | January 1, 1991 |
| Lorazepam | Developmental | 846-49-1 | |
| Lovastatin | Developmental | 75330-75-5 | |
| Lynestrenol | Cancer | 52-76-6 | |
| Malathion | Cancer | 121-75-5 | |
| Malonaldehyde, sodium salt | Cancer | 24382-04-5 | |
| Mancozeb | Cancer | 8018-01-7 | |
| Maneb | 12427-38-2 | ||
| Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole) | 68006-83-7 | ||
| Mebendazole | 31431-39-7 | ||
| Medroxyprogesterone acetate | 71-58-9 | ||
| Megestrol acetate | Cancer
Developmental |
595-33-5 | March 28, 2014
January 1, 1991 |
| MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) | 77094-11-2 | ||
| MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) | 77500-04-0 | ||
| Melphalan | 148-82-3 | ||
| Menotropins | 9002-68-0 | ||
| Mepanipyrim | 110235-47-7 | ||
| Meprobamate | 57-53-4 | ||
| 2-Mercaptobenzothiazole | 149-30-4 | ||
| Mercaptopurine | 6112-76-1 | ||
| Mercury and compounds | – | ||
| Merphalan | 531-76-0 | ||
| Mestranol | 72-33-3 | ||
| Metam potassium | 137-41-7 | ||
| Methacycline hydrochloride | Developmental | 3963-95-9 | January 1, 1991 |
| Metham sodium | 137-42-8 | ||
| Methanol | 67-56-1 | ||
| Methazole | 20354-26-1 | ||
| Methimazole | 60-56-0 | ||
| Methotrexate | 59-05-2 | ||
| Methotrexate sodium | 15475-56-6 | ||
| 5-Methoxypsoralen with ultraviolet A therapy | 484-20-8 | ||
| 8-Methoxypsoralen with ultraviolet A therapy | 298-81-7 | ||
| 2-Methylaziridine (Propyleneimine) | 75-55-8 | ||
| Methylazoxymethanol | 590-96-5 | ||
| Methylazoxymethanol acetate | 592-62-1 | ||
| Methyl bromide as fumigant | 74-83-9 | ||
| Methyl carbamate | 598-55-0 | ||
| Methyl chloride | 74-87-3 | ||
| 3-Methylcholanthrene | 56-49-5 | ||
| 5-Methylchrysene | 3697-24-3 | ||
| 4,4'-Methylene bis(2-chloroaniline) | Cancer | 101-14-4 | July 1, 1987 |
| 4,4'-Methylene bis(N,N-dimethyl)benzenamine | 101-61-1 | ||
| 4,4'-Methylene bis(2-methylaniline) | 838-88-0 | ||
| 4,4'-Methylenedianiline | 101-77-9 | ||
| 4,4'-Methylenedianiline dihydrochloride | 13552-44-8 | ||
| Methyleugenol | 93-15-2 | ||
| 2-Methylimidazole | 693-98-1 | ||
| 4-Methylimidazole | 822-36-6 | ||
| Methyl iodide | 74-88-4 | ||
| Methyl isobutyl ketone (MIBK) | 108-10-1 | ||
| Methyl isocyanate (MIC) | 624-83-9 | ||
| Methyl mercury and compounds | Developmental
Cancer |
– | July 1, 1987
May 1, 1996 |
| Methyl methanesulfonate | 66-27-3 | ||
| Methyl-n-butyl ketone | 591-78-6 | ||
| 2-Methyl-1-nitroanthraquinone | 129-15-7 | ||
| N-Methyl-N'-nitro-N-nitrosoguanidine | 70-25-7 | ||
| N-Methylolacrylamide | 924-42-5 | ||
| N-Methylpyrrolidone | 872-50-4 | ||
| α-Methyl styrene (alpha-Methylstyrene) | 98-83-9 | ||
| Methyltestosterone | 58-18-4 | ||
| Methylthiouracil | 56-04-2 | ||
| Metiram | 9006-42-2 | ||
| Metronidazole | 443-48-1 | ||
| Michler's ketone | 90-94-8 | ||
| Midazolam hydrochloride | 59467-96-8 | ||
| Minocycline hydrochloride | 13614-98-7 | ||
| Mirex | 2385-85-5 | ||
| Misoprostol | 59122-46-2 | ||
| Mitomycin C | 50-07-7 | ||
| Mitoxantrone hydrochloride | 70476-82-3 | ||
| Molybdenum trioxide | 1313-27-5 | ||
| Molinate | 2212-67-1 | ||
| MON 4660 (dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane) | 71526-07-3 | ||
| MON 13900 (furilazole) | 121776-33-8 | ||
| 3-Monochloropropane-1,2-diol (3-MCDP) | 96-24-2 | ||
| Monocrotaline | 315-22-0 | ||
| MOPP (vincristine-prednisone-nitrogen mustard-procarbazine mixture) | 113803-47-7 | ||
| 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone | 139-91-3 | ||
| Mustard Gas | 505-60-2 | ||
| MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone) | Cancer | 77439-76-0 | December 22, 2000 |
| Myclobutanil | 88671-89-0 | ||
| Beta-Myrcene | 123-35-3 | ||
| Nabam | 142-59-6 | ||
| Nafarelin acetate | 86220-42-0 | ||
| Nafenopin | 3771-19-5 | ||
| Nalidixic acid | 389-08-2 | ||
| Naphthalene | 91-20-3 | ||
| 1-Naphthylamine | 134-32-7 | ||
| 2-Naphthylamine | 91-59-8 | ||
| Neomycin sulfate | 1405-10-3 | ||
| Netilmicin sulfate | 56391-57-2 | ||
| Nickel (Metallic) | 7440-02-0 | ||
| Nickel acetate | 373-02-4 | ||
| Nickel carbonate | 3333-67-3 | ||
| Nickel carbonyl | 13463-39-3 | ||
| Nickel (soluble compounds) | – | ||
| Nickel hydroxide | 12054-48-7; 12125-56-3 | ||
| Nickelocene | 1271-28-9 | ||
| Nickel oxide | 1313-99-1 | ||
| Nickel refinery dust from the pyrometallurgical process | – | ||
| Nickel subsulfide | 12035-72-2 | ||
| Nicotine | 54-11-5 | ||
| Nifedipine | 21829-25-4 | ||
| Nimodipine | 66085-59-4 | ||
| Niridazole | 61-57-4 | ||
| Nitrapyrin | 1929-82-4 | ||
| Nitrilotriacetic acid | 139-13-9 | ||
| Nitrilotriacetic acid, trisodium salt monohydrate | 18662-53-8 | ||
| 5-Nitroacenaphthene | 602-87-9 | ||
| o-Nitroanisole | 91-23-6 | ||
| Nitrobenzene | 98-95-3 | ||
| 4-Nitrobiphenyl | 92-93-3 | ||
| 6-Nitrochrysene | Cancer | 7496-02-8 | October 1, 1990 |
| Nitrofen (technical grade) | 1836-75-5 | ||
| 2-Nitrofluorene | Cancer | 607-57-8 | October 1, 1990 |
| Nitrofurantoin | 67-20-9 | ||
| Nitrofurazone | 59-87-0 | ||
| 1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone | 555-84-0 | ||
| N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide | 531-82-8 | ||
| Nitrogen mustard (Mechlorethamine) | 51-75-2 | ||
| Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) | 55-86-7 | ||
| Nitrogen mustard N-oxide | Cancer | 126-85-2 | |
| Nitrogen mustard N-oxide hydrochloride | Cancer | 302-70-5 | |
| Nitromethane | Cancer | 75-52-5 | May 1, 1997 |
| 2-Nitropropane | Cancer | 79-46-9 | |
| 1-Nitropyrene | Cancer | 5522-43-0 | October 1, 1990 |
| 4-Nitropyrene | Cancer | 57835-92-4 | October 1, 1990 |
| N,N-Dimethylformamide | Cancer | 68-12-2 | |
| N-Nitrosodi-n-butylamine | Cancer | 924-16-3 | |
| N-Nitrosodiethanolamine | Cancer | 1116-54-7 | |
| N-Nitrosodiethylamine | Cancer | 55-18-5 | |
| N-Nitrosodimethylamine | Cancer | 62-75-9 | |
| p-Nitrosodiphenylamine | Cancer | 156-10-5 | |
| N-Nitrosodiphenylamine | Cancer | 86-30-6 | |
| N-Nitrosodi-n-propylamine | 621-64-7 | ||
| N-Nitroso-N-ethylurea | 759-73-9 | ||
| N-Nitrosohexamethyleneimine | 932-83-2 | ||
| 3-(N-Nitrosmethylamino) propionitrile | 60153-49-3 | ||
| 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone | 64091-91-4 | ||
| N-Nitrosomethyl-n-butylamine | 7068-83-9 | ||
| N-Nitrosomethyl-n-decylamine | 75881-22-0 | ||
| N-Nitrosomethyl-n-dodecylamine | 55090-44-3 | ||
| N-Nitrosomethylethylamine | 10595-95-6 | ||
| N-Nitrosomethyl-n-heptylamine | 16338-99-1 | ||
| N-Nitrosomethyl-n-hexylamine | 28538-70-7 | ||
| N-Nitrosomethyl-n-nonylamine | 75881-19-5 | ||
| N-Nitrosomethyl-n-octylamine | 34423-54-6 | ||
| N-Nitrosomethyl-n-pentylamine | 13256-07-0 | ||
| N-Nitrosomethyl-n-propylamine | 924-46-9 | ||
| N-Nitrosomethyl-n-tetradecylamine | 75881-20-8 | ||
| N-Nitrosomethyl-n-undecylamine | 68107-26-6 | ||
| N-Nitroso-N-methylurea | 684-93-5 | ||
| N-Nitroso-N-methylurethane | 615-53-2 | ||
| N-Nitrosomethylvinylamine | 4549-40-0 | ||
| N-Nitrosomorpholine | 59-89-2 | ||
| N-Nitrosonornicotine | 16543-55-8 | ||
| N-Nitrosopiperidine | 100-75-4 | ||
| N-Nitrosopyrrolidine | 930-55-2 | ||
| N-Nitrososarcosine | 13256-22-9 | ||
| o-Nitrotoluene | 88-72-2 | ||
| Nitrous oxide | 10024-97-2 | ||
| Norethisterone (Norethindrone) | 68-22-4 | ||
| Norethisterone acetate (Norethindrone acetate) | 51-98-9 | ||
| Norethynodrel | 68-23-5 | ||
| Norgestrel | 6533-00-2 | ||
| Ochratoxin A | 303-47-9 | ||
| Oil Orange SS | 2646-17-5 | ||
| Oral contraceptives, combined or sequential | – | ||
| Oryzalin | 19044-88-3 | ||
| Oxadiazon | 19666-30-9 | ||
| Oxazepam | 604-75-1 | ||
| Oxydemeton methyl | 301-12-2 | ||
| Oxymetholone | Cancer
Developmental |
434-07-1 | January 1, 1988
May 1, 1997 |
| Oxytetracycline (internal use) | Developmental | 79-57-2 | January 1, 1991 |
| Oxytetracycline hydrochloride | 2058-46-0 | ||
| Oxythioquinox (Chinomethionat) | 2439-01-2 | ||
| Paclitaxel | 33069-62-4 | ||
| Palygorskite fibers (> 5 μm in length) | 12174-11-7 | ||
| Panfuran S | 794-93-4 | ||
| Paramethadione | 115-67-3 | ||
| Parathion | 56-38-2 | ||
| Penicillamine | Developmental | 52-67-5 | January 1, 1991 |
| Pentabromodiphenyl ether mixture [DE-71 (technical grade)] | – | ||
| Pentachlorophenol | 87-86-5 | ||
| Pentachlorophenol and by-products of its synthesis (complex mixture) | – | ||
| Pentobarbital sodium | 57-33-0 | ||
| Pentosan polysulfate sodium | – | ||
| Pentostatin | 53910-25-1 | ||
| Perfluorooctane sulfonate (PFOS) | 1763-23-1 | ||
| Perfluorooctanoic acid (PFOA) | 335-67-1 | ||
| Pertuzumab | Developmental | 380610-27-5 | January 27, 2017 |
| Phenacemide | 63-98-9 | ||
| Phenacetin (in analgesic mixtures) | Cancer | 62-44-2 | |
| Phenazopyridine | 94-78-0 | ||
| Phenazopyridine hydrochloride | 136-40-3 | ||
| Phenesterin | 3546-10-9 | ||
| Phenobarbital | 50-06-6 | ||
| Phenolphthalein | 77-09-8 | ||
| Phenoxybenzamine | 59-96-1 | ||
| Phenoxybenzamine hydrochloride | 63-92-3 | ||
| Phenprocoumon | 435-97-2 | ||
| o-Phenylenediamine and its salts | 95-54-5 | ||
| Phenyl glycidyl ether | Cancer | 122-60-1 | October 1, 1990 |
| Phenylhydrazine and its salts | – | ||
| o-Phenylphenate, sodium | 132-27-4 | ||
| o-Phenylphenol | 90-43-7 | ||
| Phenylphosphine | 638-21-1 | ||
| PhiP (2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine) | 105650-23-5 | ||
| Pimozide | 2062-78-4 | ||
| Pioglitazone | 111025-46-8 | ||
| Pipobroman | 54-91-1 | ||
| Pirimicarb | 23103-98-2 | ||
| Plicamycin | 18378-89-7 | ||
| Polybrominated biphenyls | – | ||
| Polychlorinated biphenyls | Cancer
Developmental |
– | October 1, 1989
January 1, 1991 |
| Polychlorinated biphenyls (containing 60 or more percent chlorine by molecular weight) | – | ||
| Polychlorinated dibenzo-p-dioxins | – | ||
| Polychlorinated dibenzofurans | – | ||
| Polygeenan | 53973-98-1 | ||
| Ponceau MX | 3761-53-3 | ||
| Ponceau 3R | 3564-09-8 | ||
| Potassium bromate | 7758-01-2 | ||
| Potassium dimethyldithiocarbamate | 128-03-0 | ||
| Pravastatin sodium | 81131-70-6 | ||
| Prednisolone sodium phosphate | 125-02-0 | ||
| Primidone | 125-33-7 | ||
| Procarbazine | 671-16-9 | ||
| Procarbazine hydrochloride | 366-70-1 | ||
| Procymidone | 32809-16-8 | ||
| Progesterone | 57-83-0 | ||
| Pronamide | 23950-58-5 | ||
| Propachlor | 1918-16-7 | ||
| 1,3-Propane sultone | 1120-71-4 | ||
| Propargite | 2312-35-8 | ||
| Propazine | 139-40-2 | ||
| beta-Propiolactone | 57-57-8 | ||
| Propoxur | 114-26-1 | ||
| Propylene glycol mono-t-butyl ether | 57018-52-7 | ||
| Propylene oxide | 75-56-9 | ||
| Propylthiouracil | 51-52-5 | ||
| Pulegone | 89-82-7 | ||
| Pymetrozine | 123312-89-0 | ||
| Pyridine | 110-86-1 | ||
| Pyrimethamine | 58-14-0 | ||
| Quazepam | 36735-22-5 | ||
| Quinoline and its strong acid salts | – | ||
| Quizalofop-ethyl | 76578-14-8 | ||
| Radionuclides | – | ||
| Reserpine | 50-55-5 | ||
| Residual (heavy) fuel oils | Cancer | – | October 1, 1990 |
| Resmethrin | 10453-86-8 | ||
| Retinol/retinyl esters [refer 1] | – | ||
| Ribavirin | 36791-04-5 | ||
| Riddelliine | 23246-96-0 | ||
| Rifampin | 13292-46-1 | ||
| Safrole | 94-59-7 | ||
| Salted fish, Chinese-style | – | ||
| Secobarbital sodium | 309-43-3 | ||
| Sedaxane | 874967-67-6 | ||
| Selenium sulfide | 7446-34-6 | ||
| Sermorelin acetate | – | ||
| Shale oils | 68308-34-9 | ||
| Silica, crystalline (airborne particles of respirable size) | – | ||
| Silicon carbide whiskers | – | ||
| Simazine | 122-34-9 | ||
| Sodium dimethyldithiocarbamate | 128-04-1 | ||
| Sodium fluoroacetate | 62-74-8 | ||
| Soots, tars, and mineral oils (untreated and mildly treated oils and used engine oils) | – | ||
| Spirodiclofen | 148477-71-8 | ||
| Spironolactone | Cancer | 52-01-7 | May 1, 1997 |
| Stanozolol | Cancer | 10418-03-8 | May 1, 1997 |
| Sterigmatocystin | Cancer | 10048-13-2 | |
| Streptomycin sulfate | Developmental | 3810-74-0 | January 1, 1991 |
| Streptozocin (streptozotocin) | Developmental
Reproductive toxicity (female, male) |
18883-66-4 | |
| Strong inorganic acid mists containing sulfuric acid | Cancer | – | |
| Styrene | Cancer | 100-42-5 | |
| Styrene oxide | 96-09-3 | ||
| Sulfallate | 95-06-7 | ||
| Sulfasalazine (Salicylazosulfapyridine) | 599-79-1 | ||
| Sulfur dioxide | 7446-09-5 | ||
| Sulindac | 38194-50-2 | ||
| Talc containing asbestiform fibers | – | ||
| Tamoxifen | 10540-29-1 | ||
| Tamoxifen citrate | 54965-24-1 | ||
| Temazepam | 846-50-4 | ||
| Teniposide | 29767-20-2 | ||
| Terbacil | 5902-51-2 | ||
| Teriparatide | 52232-67-4 | ||
| Terrazole | 2593-15-9 | ||
| Testosterone | 58-22-0 | ||
| Testosterone cypionate | 58-20-8 | ||
| Testosterone enanthate | 315-37-7 | ||
| Tetrabromobisphenol A | 79-94-7 | ||
| 3,3',4,4'-Tetrachloroazobenzene | 14047-09-7 | ||
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) | 1746-01-6 | ||
| 1,1,1,2-Tetrachloroethane | 630-20-6 | ||
| 1,1,2,2-Tetrachloroethane | 79-34-5 | ||
| Tetrachloroethylene (Perchloroethylene) | 127-18-4 | ||
| p-α,α,α-Tetrachlorotoluene | 5216-25-1 | ||
| Tetrachlorvinphos | 22248-79-9 | ||
| Tetracycline (internal use) | Developmental | 60-54-8 | |
| Tetracyclines (internal use) | Developmental | – | |
| Tetracycline hydrochloride (internal use) | Developmental | 64-75-5 | January 1, 1991 |
| Tetrafluoroethylene | Cancer | 116-14-3 | May 1, 1997 |
| Tetranitromethane | 509-14-8 | July 1, 1990 | |
| Thalidomide | Developmental | 50-35-1 | July 1, 1987 |
| Thioacetamide | 62-55-5 | ||
| Titanium dioxide | 13463-67-7 | ||
| 4,4'-Thiodianiline | 139-65-1 | ||
| Thiodicarb | 59669-26-0 | ||
| Thioguanine | 154-42-7 | ||
| Thiophanate methyl | 23564-05-8 | ||
| 2-Thiouracil | 141-90-2 | ||
| Thiourea | 62-56-6 | ||
| Thorium dioxide | 1314-20-1 | ||
| Tobacco, oral use of smokeless products | – | ||
| Tobacco smoke | – | ||
| Tobacco smoke (Primary) | – | ||
| Tobramycin sulfate | 49842-07-1 | ||
| Toluene | Developmental | 108-88-3 | January 1, 1991 |
| Toluene diisocyanate | 26471-62-5 | ||
| o-Toluidine | 95-53-4 | ||
| o-Toluidine hydrochloride | 636-21-5 | ||
| Topiramate | 97240-79-4 | ||
| Toxaphene (Polychlorinated camphenes) | 8001-35-2 | ||
| Fusarium toxins | – | ||
| Treosulfan | 299-75-2 | ||
| Triadimefon | 43121-43-3 | ||
| Triamterene | 396-01-0 | ||
| Triazolam | 28911-01-5 | ||
| S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF) | 78-48-8 | ||
| Tributyltin methacrylate | 2155-70-6 | ||
| Trichlormethine (Trimustine hydrochloride) | 817-09-4 | ||
| Trichloroacetic acid | 76-03-9 | ||
| 1,1,1-Trichloroethane | 71-55-6 | ||
| Trichloroethylene | 79-01-6 | ||
| 2,4,6-Trichlorophenol | 88-06-2 | ||
| 1,2,3-Trichloropropane | 96-18-4 | ||
| Trientine hydrochloride | 38260-01-4 | ||
| Triforine | 26644-46-2 | ||
| Trilostane | Developmental | 13647-35-3 | |
| Trimethadione | Developmental | 127-48-0 | January 1, 1991 |
| 2,4,5-Trimethylaniline | – | ||
| Trimethyl phosphate | 512-56-1 | ||
| Trimetrexate glucuronate | 82952-64-5 | ||
| TRIM VX | – | ||
| 2,4,6-Trinitrotoluene (TNT) | 118-96-7 | ||
| Triphenyltin hydroxide | 76-87-9 | ||
| Tris(1-aziridinyl)phosphine sulfide (Thiotepa) | 52-24-4 | ||
| Tris(2-chloroethyl) phosphate | 115-96-8 | ||
| Tris(2,3-dibromopropyl)phosphate | 126-72-7 | ||
| Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) | 13674-87-8 | ||
| Trp-P-1 (Tryptophan-P-1) | 62450-06-0 | ||
| Trp-P-2 (Tryptophan-P-2) | 62450-07-1 | ||
| Trypan blue | 72-57-1 | ||
| Unleaded gasoline | – | ||
| Uracil mustard | 66-75-1 | ||
| Urethane (Ethyl carbamate) | 51-79-6 | ||
| Urofollitropin | 97048-13-0 | ||
| Valproate (Valproic acid) | Developmental | 99-66-1 | July 1, 1987 |
| Vanadium pentoxide (only orthorhombic) | 1314-62-1 | ||
| Vinblastine sulfate | 143-67-9 | ||
| Vinclozolin | 50471-44-8 | ||
| Vincristine sulfate | 2068-78-2 | ||
| Vinyl acetate | Cancer | 108-05-4 | January 3, 2025 |
| Vinyl bromide | 593-60-2 | ||
| Vinyl chloride | 75-01-4 | ||
| 4-Vinylcyclohexene | 100-40-3 | ||
| 4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexenedioxide) | 106-87-6 | ||
| Vinyl fluoride | Cancer | 75-02-5 | May 1, 1997 |
| Vinylidene chloride (1,1-Dichloroethylene) | Cancer | 75-35-4 | December 29, 2017 |
| Vinyl trichloride (1,1,2-Trichloroethane) | Cancer | 79-00-5 | October 1, 1990 |
| Vismodegib | Developmental
Reproductive toxicity (female, male) |
879085-55-9 | January 27, 2017 |
| Warfarin | Developmental | 81-81-2 | July 1, 1987 |
| Wood dust | Cancer | – | December 18, 2009 |
| 2,6-Xylidine (2,6-Dimethylaniline) | Cancer | 87-62-7 | January 1, 1991 |
| Zalcitabine | Cancer | 7481-89-2 | |
| Zidovudine (AZT) | Cancer | 30516-87-1 | December 18, 2009 |
| Zileuton | Cancer
Developmental Reproductive toxicity (female) |
111406-87-2 | December 22, 2000 |
Annotation
- When in daily dosages in excess of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/retinyl esters arerequired and essential for maintenance of normal reproductive function. The recommended daily level during pregnancy is 8,000 IU.)
Chemicals that were formerly listed under California Proposition 65
Summarize
Perspective
| Substance | CAS Registry Number † | Date removed |
|---|---|---|
| Bisphenol A (BPA) | 80-05-7 | April 11, 2013 |
| Allyl chloride | 107-05-1 | October 29, 1999 |
| Phenyl glycidyl ether | 122-60-1 | April 4, 2014 |
| α-Methyl styrene | 98-83-9 | April 4, 2014 |
| tert-Amyl methyl ether | 994-05-8 | December 13, 2013 |
| n-Butyl glycidyl ether | 2426-08-6 | April 4, 2014 |
| Chloramphenicol | 56-75-7 | January 4, 2013 |
| Chlorodibromomethane | 124-48-1 | October 29, 1999 |
| Chlorsulfuron | 64902-72-3 | June 6, 2014 |
| Cyclohexanol | 108-93-0 | January 25, 2002 |
| Diaminotoluene (mixed) | – | November 20, 2015 |
| Dienestrol | 84-17-3 | January 4, 2013 |
| Diglycidyl ether | 2238-07-5 | April 4, 2014 |
| 2,4-DP (dichloroprop) | 120-36-5 | January 25, 2002 |
| Ethyl-tert-butyl ether | 637-92-3 | December 13, 2013 |
| 2-Ethylhexanoic acid | 149-57-5 | December 13, 2013 |
| Isosafrole | 120-58-1 | December 8, 2006 |
| Methyl isopropyl ketone | 563-80-4 | April 4, 2014 |
| 5-Nitro-o-anisidine | 99-59-2 | December 8, 2006 |
| p,p'-Oxybis(benzenesulfonyl hydrazide) | 80-51-3 | December 13, 2013 |
| Saccharin | 81-07-2 | April 6, 2001 |
| Saccharin, sodium | 128-44-9 | January 17, 2003 |
| para-Toluidine | 106-49-0 | October 29, 1999 |
| 1,3,5-Triglycidyl-s-triazinetrione | 2451-62-9 | December 13, 2013 |
| Tris(aziridinyl)-p-benzoquinone (Triaziquone) | 68-76-8 | December 8, 2006 |
| Zineb | 12122-67-7 | October 29, 1999 |
† Numerical identifier assigned by the Chemical Abstracts Service (CAS)
Comments:
- Many substances include its strong acid salts
- Airborne particles of many substances are cancerogenic
- Bisphenol A (BPA) was removed from the list on April 19, 2013, and was relisted on May 11, 2015.
References
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