2022 Challenger Ciudad de Guayaquil – Singles

Alejandro Tabilo was the defending champion^[1] but chose not to defend his title.

Singles
2022 Challenger Ciudad de Guayaquil
Champion	Daniel Altmaier
Runner-up	Federico Coria
Score	6–2, 6–4

Main article: 2022 Challenger Ciudad de Guayaquil

Daniel Altmaier won the title after defeating Federico Coria 6–2, 6–4 in the final.

Seeds

1. Federico Coria (final)
2. Tomás Martín Etcheverry (first round)
3. Daniel Altmaier (champion)
4. Juan Pablo Varillas (semifinals)
5. Juan Manuel Cerúndolo (second round)
6. Franco Agamenone (second round)
7. Santiago Rodríguez Taverna (first round)
8. Felipe Meligeni Alves (second round)

Draw

Key

• Q = Qualifier
• WC = Wild card
• LL = Lucky loser
• Alt = Alternate
• ITF = ITF entry
• PR = Protected ranking
• SR = Special ranking
• SE = Special exempt
• JE = Junior exempt
• JR = Junior Accelerator Programme entrant
• CO = College Accelerator Programme entrant
• NG = Next Gen Accelerator Program entrant
• w/o = Walkover
• r = Retired
• d = Defaulted

Finals

	Semifinals							Final
	1	Federico Coria	6	2	77
	4	Juan Pablo Varillas	4	6	64
								1	Federico Coria	2	4
								3	Daniel Altmaier	6	6
	3	Daniel Altmaier	77	6
	Q	Marco Cecchinato	64	4

Top half

	First round							Second round							Quarterfinals							Semifinals
	1	F Coria	6	78
		F Comesaña	2	66				1	F Coria	3	6	77
	Alt	N Milojević	61	2					F Díaz Acosta	6	1	62
		F Díaz Acosta	77	6											1	F Coria	6	6
	Alt	N Sánchez Izquierdo	1	68												M Pucinelli de Almeida	4	4
		M Pucinelli de Almeida	6	710					M Pucinelli de Almeida	6	6
	Q	Juan Ignacio Galarza	4	63				8	F Meligeni Alves	3	4
	8	F Meligeni Alves	6	77																		1	F Coria	6	2	77
	4	JP Varillas	6	6																		4	JP Varillas	4	6	64
	Q	E Ribeiro	2	1				4	JP Varillas	6	77
	WC	Á Guillén Meza	6	6				WC	A Guillén Meza	1	63
	WC	A Andrade	4	3											4	JP Varillas	6	6
	PR	S Nagal	6	6												N Kicker	1	3
		D Dutra da Silva	2	1				PR	S Nagal	1	6	5
		N Kicker	6	6					N Kicker	6	3	7
	7	S Rodríguez Taverna	1	4

Bottom half

	First round							Second round							Quarterfinals							Semifinals
	6	F Agamenone	7	6
	WC	C March	5	1				6	F Agamenone	2	6	4
		H Casanova	1	77	5				J de Jong	6	4	6
		J de Jong	6	65	7											J de Jong	2	6	3
	Alt	R Quiroz	3	62											3	D Altmaier	6	3	6
		JB Torres	6	77					JB Torres	4	3
	Q	T Seyboth Wild	6	65	2			3	D Altmaier	6	6
	3	D Altmaier	1	77	6																	3	D Altmaier	77	6
	5	JM Cerúndolo	6	6																		Q	M Cecchinato	64	4
		G Melzer	4	2				5	JM Cerúndolo	77	2	4
		TA Tirante	3	65				Q	J Choinski	63	6	6
	Q	J Choinski	6	77											Q	J Choinski	1	3
	Q	M Cecchinato	6	6											Q	M Cecchinato	6	6
	Q	B Bicknell	1	3				Q	M Cecchinato	6	2
	LL	RA Burruchaga	63	7	7			LL	RA Burruchaga	1	0r
	2	TM Etcheverry	77	5	5