![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/8/88/WhitingReaction.png/640px-WhitingReaction.png&w=640&q=50)
Whiting reaction
Chemical reaction / From Wikipedia, the free encyclopedia
The Whiting reaction is an organic reaction converting a propargyl diol into a diene using lithium aluminium hydride.[1]
![Whiting reaction](http://upload.wikimedia.org/wikipedia/commons/thumb/3/36/WhitingReactionGeneral.png/640px-WhitingReactionGeneral.png)
This organic reduction has been applied in the synthesis of fecapentaene, a suspected cause of colon cancer:[2]
Protecting groups are tetrahydropyranyl and TBSMS; the final step is deprotection with tetra-n-butylammonium fluoride.