User:Mr. Ibrahem/Oxandrolone
From Wikipedia, the free encyclopedia
Oxandrolone, sold under the brand names Oxandrin among others, is a manufactured androgen and anabolic steroid (AAS).[4] It is used to promote weight gain in those losing weight, prevent protein breakdown caused by long-term corticosteroids, and bone pain associated with osteoporosis.[4][5] It is taken by mouth.[4]
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Trade names | Oxandrin, Anavar, others |
Other names | Var; CB-8075; NSC-67068; SC-11585; Protivar; 17α-Methyl-2-oxa-4,5α-dihydrotestosterone; 17α-Methyl-2-oxa-DHT; 17α-Methyl-2-oxa-5α-androstan-17β-ol-3-one |
AHFS/Drugs.com | Monograph |
MedlinePlus | a604024 |
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Routes of administration | By mouth |
Drug class | Androgen; anabolic steroid |
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Pharmacokinetic data | |
Bioavailability | 97%[1] |
Protein binding | 94–97%[1] |
Metabolism | Kidneys (primarily), liver[2][1] |
Elimination half-life | Adults: 9.4–10.4 hours[1][3] Elderly: 13.3 hours[3] |
Excretion | Urine: 28% (unchanged)[3] Feces: 3%[3] |
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Chemical and physical data | |
Formula | C19H30O3 |
Molar mass | 306.446 g·mol−1 |
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Common side effects include liver problems and lipid abnormalities.[4] Other side effects may include heart failure, misuse, acne, increased hair growth, and voice changes.[4] Use during pregnancy may harm the baby.[4] Oxandrolone activates the androgen receptor (AR), the biological target of testosterone.[6] It has greater anabolic than androgenic effects.[4]
Oxandrolone was approved for medical use in the United States in 1964.[4] It is not medically available in the United Kingdom.[6] In the United States 60 tablets of 10 mg costs about 284 USD as of 2020.[7] It has also been inappropriately used to improve physique and performance in sports.[4] It is a controlled substance in many countries, so nonmedical is generally illegal.[8][9][10]