User:KatieBNL/sandbox
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This is a work in progress for the daptomycin page. Any feedback would be appreciated. --K. Beabout (talk) 15:58, 4 June 2013 (UTC)
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Cubicin |
AHFS/Drugs.com | Monograph |
Routes of administration | Intravenous |
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Pharmacokinetic data | |
Bioavailability | n/a |
Protein binding | 90–95% |
Metabolism | Renal (speculative)[1] |
Elimination half-life | 7–11 hours (up to 28 hours in renal impairment) |
Excretion | Renal (78%; primarily as unchanged drug); Faeces (5.7%) |
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Chemical and physical data | |
Formula | C72H101N17O26 |
Molar mass | 1619.7086 g/mol g·mol−1 |
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Quick Facts Identifiers, Symbol ...
Identifiers | |
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Symbol | ? |
TCDB | 1.D.15 |
OPM superfamily | 172 |
OPM protein | 1t5n |
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Daptomycin is a lipopeptide antibiotic used in the treatment of systemic and life-threatening infections caused by Gram-positive organisms. It is a naturally occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action makes it useful in treating infections caused by multi-resistant bacteria. It is marketed in the United States under the trade name Cubicin by Cubist Pharmaceuticals.