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UBE2L3
Protein-coding gene in humans / From Wikipedia, the free encyclopedia
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Ubiquitin-conjugating enzyme E2 L3 (UBE2L3), also called UBCH7, is a protein that in humans is encoded by the UBE2L3 gene.[5][6][7] As an E2 enzyme, UBE2L3 participates in ubiquitination to target proteins for degradation.[7] The role of UBE2L3 in the ubiquitination of the NF-κB precursor implicated it in various major autoimmune diseases, including rheumatoid arthritis (RA), celiac disease, Crohn's disease (CD), and systemic lupus erythematosus.[8]
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