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20α-Dihydrotrengestone
Chemical compound / From Wikipedia, the free encyclopedia
20α-Dihydrotrengestone (20α-DHTG), also known as 20α-hydroxytrengestone, as well as 6-chloro-20(S)-hydroxy-9β,10α-pregna-1,4,6-trien-3-one, is a progestin and the major active metabolite of trengestone.[1][2] It appears that trengestone is a prodrug of 20α-DHTG, as it is largely transformed into this metabolite when given orally in humans.[2][1] 20α-DHTG has potent progestogenic activity similarly to trengestone.[1]
Quick Facts Clinical data, Other names ...
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Clinical data | |
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Other names | 20α-DHTG; 20α-Hydroxytrengestone; 6-Chloro-20(S)-hydroxy-9β,10α-pregna-1,4,6-trien-3-one |
Drug class | Progestin; Progestogen |
Pharmacokinetic data | |
Elimination half-life | 8–14 hours[1] |
Chemical and physical data | |
Formula | C21H26ClO2 |
Molar mass | 345.89 g·mol−1 |
3D model (JSmol) | |
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