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The 2022 Karlsruhe Open (also known as the Liqui Moly Open for sponsorship reasons) was a professional tennis tournament played on outdoor clay courts. It was the 3rd edition of the tournament and part of the 2022 WTA 125 tournaments, offering a total of $115,000 in prize money. It took place in Karlsruhe, Germany between 10 and 15 May 2022.[1]
| 2022 Karlsruhe Open | |
|---|---|
| Date | 10 – 15 May |
| Edition | 3rd |
| Category | WTA 125 |
| Draw | 32S / 8D |
| Prize money | $115,000 |
| Surface | Clay |
| Location | Karlsruhe, Germany |
| Venue | TC Rüppurr |
| Champions | |
| Singles | |
 Mayar Sherif | |
| Doubles | |
Mayar Sherif / 
Panna Udvardy | |
Seeds
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BEL |
Alison Van Uytvanck | 59 | 1 |
| EGY |
Mayar Sherif | 61 | 2 |
| HUN |
Anna Bondár | 68 | 3 |
| BEL |
Greet Minnen | 79 | 4 |
| HUN |
Panna Udvardy | 83 | 5 |
 FRA |
Clara Burel | 84 | 6 |
| HUN |
Dalma Gálfi | 91 | 7 |
 USA |
Bernarda Pera | 100 | 8 |
- 1 Rankings as of 25 April 2022.
Other entrants
The following players received a wildcard into the singles main draw:
The following players received entry into the singles main draw through protected ranking:
Withdrawals
- Before the tournament
Irina Bara → replaced by 
Bibiane Schoofs
Harriet Dart → replaced by 
Katarzyna Kawa
Vitalia Diatchenko → replaced by 
Kathinka von Deichmann
Seeds
| Country | Player | Country | Player | Rank1 | Seed |
|---|---|---|---|---|---|
 POL |
Katarzyna Piter | BEL |
Kimberley Zimmermann | 157 | 1 |
 SVK |
Tereza Mihalíková | BEL |
Greet Minnen | 158 | 2 |
- 1 Rankings as of 25 April 2022.
Other entrants
The following pair received a wildcard into the doubles main draw:
Singles
Mayar Sherif def. 
Bernarda Pera 6–2, 6–4
Doubles
- Mayar Sherif /
Panna Udvardy def. Yana Sizikova / 
Alison Van Uytvanck 5–7, 6–4, [10–2]
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