Protein sy'n cael ei godio yn y corff dynol gan y genyn RBX1 yw RBX1 a elwir hefyd yn Ring-box 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 22, band 22q13.2.[2]
Ffeithiau sydyn Strwythurau, PDB ...
RBX1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/1/1d/Protein_RBX1_PDB_1ldj.png/250px-Protein_RBX1_PDB_1ldj.png) |
Strwythurau |
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PDB | Human UniProt search: PDBe RCSB |
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Dynodwyr |
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Cyfenwau | RBX1, BA554C12.1, RNF75, ROC1, ring-box 1 |
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Dynodwyr allanol | OMIM: 603814 HomoloGene: 6872 GeneCards: RBX1 |
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Ontoleg y genyn |
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Gweithrediad moleciwlaidd | • cullin family protein binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • zinc ion binding • metal ion binding • ubiquitin-ubiquitin ligase activity • GO:0001948, GO:0016582 protein binding • ubiquitin protein ligase binding • GO:0050372 ubiquitin-protein transferase activity • NEDD8 transferase activity • transcription factor binding • transferase activity • GO:0032403 protein-containing complex binding
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Cydrannau o'r gell | • cytoplasm • cullin-RING ubiquitin ligase complex • cytosol • SCF ubiquitin ligase complex • VCB complex • Cul2-RING ubiquitin ligase complex • Cul3-RING ubiquitin ligase complex • Cul5-RING ubiquitin ligase complex • Cul7-RING ubiquitin ligase complex • Cul4A-RING E3 ubiquitin ligase complex • Cul4B-RING E3 ubiquitin ligase complex • cnewyllyn cell • nucleoplasm • nuclear SCF ubiquitin ligase complex • Cul4-RING E3 ubiquitin ligase complex
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Prosesau biolegol | • nucleotide-excision repair, DNA damage recognition • protein monoubiquitination • MAPK cascade • cellular response to DNA damage stimulus • protein neddylation • global genome nucleotide-excision repair • GO:0044257 protein catabolic process • regulation of transcription from RNA polymerase II promoter in response to hypoxia • transcription-coupled nucleotide-excision repair • nucleotide-excision repair, DNA incision • negative regulation of canonical Wnt signaling pathway • nucleotide-excision repair, preincision complex stabilization • GO:0100026 DNA repair • GO:0022415 viral process • protein polyubiquitination • nucleotide-excision repair, preincision complex assembly • nucleotide-excision repair, DNA incision, 5'-to lesion • Wnt signaling pathway • SCF complex assembly • negative regulation of G2/M transition of mitotic cell cycle • post-translational protein modification • positive regulation of proteasomal ubiquitin-dependent protein catabolic process • interleukin-1-mediated signaling pathway • protein ubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • proteasome-mediated ubiquitin-dependent protein catabolic process • ubiquitin-dependent protein catabolic process • nucleotide-excision repair, DNA duplex unwinding • nucleotide-excision repair, DNA incision, 3'-to lesion
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Sources:Amigo / QuickGO |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Cau