Protein sy'n cael ei godio yn y corff dynol gan y genyn LDB1 yw LDB1 a elwir hefyd yn LIM domain binding 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q24.32.[2]
Ffeithiau sydyn Strwythurau, PDB ...
LDB1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Protein_LDB1_PDB_2XJY.png/250px-Protein_LDB1_PDB_2XJY.png) |
Strwythurau |
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PDB | Human UniProt search: PDBe RCSB |
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Dynodwyr |
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Cyfenwau | LDB1, CLIM2, NLI, CLIM-2, LDB-1, LIM domain binding 1 |
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Dynodwyr allanol | OMIM: 603451 HomoloGene: 2891 GeneCards: LDB1 |
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Ontoleg y genyn |
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Gweithrediad moleciwlaidd | • DNA binding • protein homodimerization activity • GO:0001106 transcription corepressor activity • LIM domain binding • chromatin binding • protein self-association • GO:0001948, GO:0016582 protein binding • GO:0001158 cis-regulatory region sequence-specific DNA binding • enzyme binding • GO:0001104 transcription coregulator activity
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Cydrannau o'r gell | • transcription regulator complex • cnewyllyn cell • cell leading edge • nucleoplasm • beta-catenin-TCF complex • GO:0009327 protein-containing complex
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Prosesau biolegol | • hair follicle development • transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery • epithelial structure maintenance • GO:0009373 regulation of transcription, DNA-templated • positive regulation of hemoglobin biosynthetic process • somatic stem cell population maintenance • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • gastrulation with mouth forming second • cerebellar Purkinje cell differentiation • regulation of DNA-templated transcription, elongation • head development • histone H3-K4 acetylation • Wnt signaling pathway • transcription by RNA polymerase II • transcription, DNA-templated • cerebellum development • negative regulation of erythrocyte differentiation • multicellular organism development • neuron differentiation • anterior/posterior axis specification • cellular component assembly • GO:0045996 negative regulation of transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of cell adhesion • regulation of focal adhesion assembly • regulation of cell migration • regulation of kinase activity • regulation of hematopoietic stem cell differentiation • GO:1901227 negative regulation of transcription by RNA polymerase II
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Sources:Amigo / QuickGO |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Cau