Protein sy'n cael ei godio yn y corff dynol gan y genyn ADCYAP1 yw ADCYAP1 a elwir hefyd yn Adenylate cyclase activating polypeptide 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18p11.32.[2]
Ffeithiau sydyn Strwythurau, PDB ...
ADCYAP1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e2/Protein_ADCYAP1_PDB_2d2p.png/250px-Protein_ADCYAP1_PDB_2d2p.png) |
Strwythurau |
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PDB | Human UniProt search: PDBe RCSB |
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Dynodwyr |
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Cyfenwau | ADCYAP1, PACAP, adenylate cyclase activating polypeptide 1 |
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Dynodwyr allanol | OMIM: 102980 HomoloGene: 869 GeneCards: ADCYAP1 |
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Ontoleg y genyn |
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Gweithrediad moleciwlaidd | • pituitary adenylate cyclase activating polypeptide activity • hormone activity • peptide hormone receptor binding • GO:0001948, GO:0016582 protein binding • pituitary adenylate cyclase-activating polypeptide receptor binding • neuropeptide hormone activity • signaling receptor binding
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Cydrannau o'r gell | • intracellular anatomical structure • extracellular region • terminal bouton • extracellular space • neuron projection • perikaryon • cell body fiber
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Prosesau biolegol | • histamine secretion • pituitary gland development • regulation of G protein-coupled receptor signaling pathway • negative regulation of glial cell proliferation • female pregnancy • cell-cell signaling • negative regulation of cell cycle • negative regulation of muscle cell apoptotic process • behavioral fear response • nervous system development • activation of adenylate cyclase activity • regulation of protein localization • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • ATP metabolic process • negative regulation of acute inflammatory response to non-antigenic stimulus • regulation of oligodendrocyte progenitor proliferation • cellular response to glucocorticoid stimulus • GO:1901313 positive regulation of gene expression • GO:0034259 negative regulation of GTPase activity • positive regulation of synaptic transmission, glutamatergic • positive regulation of chemokine (C-C motif) ligand 5 production • regulation of postsynaptic membrane potential • positive regulation of cell population proliferation • negative regulation of potassium ion transport • positive regulation of ERK1 and ERK2 cascade • positive regulation of interleukin-6 production • positive regulation of neuron projection development • response to starvation • ovarian follicle development • sensory perception of pain • response to ethanol • negative regulation of acute inflammatory response to antigenic stimulus • neuropeptide signaling pathway • neuron projection development • cAMP-mediated signaling • positive regulation of somatostatin secretion • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • positive regulation of protein kinase activity • regulation of protein phosphorylation • positive regulation of cytosolic calcium ion concentration • insulin secretion • positive regulation of growth hormone secretion • regulation of signaling receptor activity • G protein-coupled receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • positive regulation of cAMP-mediated signaling • brain development • camera-type eye development • positive regulation of cold-induced thermogenesis
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Sources:Amigo / QuickGO |
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Orthologau |
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Species | Bod dynol | Llygoden |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Lleoliad (UCSC) | n/a | n/a |
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PubMed search | [1] | n/a |
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Wicidata |
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Cau