RNH1

Inhibitor ribonukleaze je enzim koji je kod ljudi kodiran genom RNH1.^[5]

RNH1
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 1Z7X, 1A4Y, 2BEX, 2Q4G
Identifikatori
Aliasi	RNH1
Vanjski ID-jevi	OMIM: 173320 MGI: 1195456 HomoloGene: 2204 GeneCards: RNH1
Lokacija gena (čovjek) Hrom. Hromosom 11 (čovjek)[1] Bend 11p15.5 Početak 494,512 bp[1] Kraj 507,300 bp[1]
Lokacija gena (miš) Hrom. Hromosom 7 (miš)[2] Bend 7|7 F5 Početak 140,740,239 bp[2] Kraj 140,752,770 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • ribonuclease inhibitor activity • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • angiogenin-PRI complex • Egzosom • nukleoplazma • citoplazma • citosol Biološki proces • regulation of angiogenesis • mRNA catabolic process • GO:0048553 negative regulation of catalytic activity Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	6050	107702
Ensembl	ENSG00000276230 ENSG00000023191	ENSMUSG00000038650
UniProt	P13489	Q91VI7
RefSeq (mRNK)	NM_002939 NM_203383 NM_203384 NM_203385 NM_203386 NM_203387 NM_203388 NM_203389	NM_001172100 NM_001172101 NM_145135
RefSeq (bjelančevina)	NP_002930 NP_976317 NP_976318 NP_976319 NP_976320 NP_976321 NP_976322 NP_976323	NP_001165571 NP_001165572 NP_660117
Lokacija (UCSC)	Chr 11: 0.49 – 0.51 Mb	Chr 7: 140.74 – 140.75 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 461 aminokiselina, a molekulska težina 49.973 Da.^[6]

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSLDIQSLDI		QCEELSDARW		AELLPLLQQC		QVVRLDDCGL		TEARCKDISS
ALRVNPALAE		LNLRSNELGD		VGVHCVLQGL		QTPSCKIQKL		SLQNCCLTGA
GCGVLSSTLR		TLPTLQELHL		SDNLLGDAGL		QLLCEGLLDP		QCRLEKLQLE
YCSLSAASCE		PLASVLRAKP		DFKELTVSNN		DINEAGVRVL		CQGLKDSPCQ
LEALKLESCG		VTSDNCRDLC		GIVASKASLR		ELALGSNKLG		DVGMAELCPG
LLHPSSRLRT		LWIWECGITA		KGCGDLCRVL		RAKESLKELS		LAGNELGDEG
ARLLCETLLE		PGCQLESLWV		KSCSFTAACC		SHFSSVLAQN		RFLLELQISN
NRLEDAGVRE		LCQGLGQPGS		VLRVLWLADC		DVSDSSCSSL		AATLLANHSL
RELDLSNNCL		GDAGILQLVE		SVRQPGCLLE		QLVLYDIYWS		EEMEDRLQAL
EKDKPSLRVI		S