Z0 sistem određivanja spola je sistem koji određuje spol potomaka u nekoliko moljaca, red Lepidoptera. Kod tih vrsta postoji jedan spolni hromosom, Z. Mužjaci imaju dva Z hromosoma, dok ženke imaju jedan Z. Alosomska konstitucija mužjaka je ZZ, a ženki Z0.[1][2][3]
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