Protein za popravku DNK koji nadopunjuje ćelije XP-A je protein koji je kod ljudi kodiran genom XPA , sa hromosoma 9.[4]
Kratke činjenice Dostupne strukture, PDB ...
XPA |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/b/ba/Protein_XPA_PDB_1d4u.png/250px-Protein_XPA_PDB_1d4u.png) |
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Identifikatori |
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Aliasi | XPA |
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Vanjski ID-jevi | OMIM: 611153 MGI: 99135 HomoloGene: 37298 GeneCards: XPA |
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Ontologija gena |
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Molekularna funkcija | • vezivanje iona metala • protein domain specific binding • protein homodimerization activity • vezivanje sa DNK • GO:0001948, GO:0016582 vezivanje za proteine • oštećeno vezivanje sa DNK
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Ćelijska komponenta | • intercellular bridge • Replikacijski protein A • nucleotide-excision repair factor 1 complex • jedro • nukleoplazma • citoplazma
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Biološki proces | • nucleotide-excision repair, DNA incision • intrinsic apoptotic signaling pathway in response to DNA damage • transcription-coupled nucleotide-excision repair • GO:0001306 response to oxidative stress • cellular response to DNA damage stimulus • response to auditory stimulus • multicellular organism growth • global genome nucleotide-excision repair • response to toxic substance • response to UV • nucleotide-excision repair, preincision complex assembly • Popravak ekscizijom nukleotida • nucleotide-excision repair, DNA incision, 5'-to lesion • nucleotide-excision repair involved in interstrand cross-link repair • UV-damage excision repair • base-excision repair • nucleotide-excision repair, preincision complex stabilization • nucleotide-excision repair, DNA damage recognition • GO:0100026 Popravka DNK • UV protection • protein localization to nucleus • regulation of autophagy • nucleotide-excision repair, DNA duplex unwinding • nucleotide-excision repair, DNA incision, 3'-to lesion
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Izvori:Amigo / QuickGO |
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Ortolozi |
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Vrste | Čovjek | Miš |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNK) | | |
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RefSeq (bjelančevina) | | |
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Lokacija (UCSC) | n/a | Chr 4: 46.16 – 46.2 Mb |
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PubMed pretraga | [2] | [3] |
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Wikipodaci |
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Zatvori